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Research on Breast Health Management and Prevention Strategies 乳房健康管理和预防策略研究
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2303
Minhua Xiao, Peng Tan
This article delves into the prevention, treatment, and health management of breast cancer. It first analyzes the risk factors of breast cancer and discusses strategies to prevent breast cancer by changing lifestyles and conducting early screening. It then reviews the treatment methods and latest research progress of breast cancer. Finally, it explores the quality of life and mental health issues of breast cancer patients, as well as health management strategies and lifestyle guidelines.
本文深入探讨了乳腺癌的预防、治疗和健康管理。文章首先分析了乳腺癌的危险因素,讨论了通过改变生活方式和进行早期筛查来预防乳腺癌的策略。然后,文章回顾了乳腺癌的治疗方法和最新研究进展。最后,它探讨了乳腺癌患者的生活质量和心理健康问题,以及健康管理策略和生活方式指南。
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引用次数: 0
Study on the Construction of Family Support System for Unrelated Hematopoietic Stem Cell Donation Volunteers 非亲缘造血干细胞捐献志愿者家庭支持系统建设研究
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2311
Wenjie Ge, Yi Zheng
There are millions of patients in urgent need of hematopoietic stem cell transplantation in China, but the matching success rate of unrelated hematopoietic stem cells is only 1/400 ~ 1/10000. Since the establishment of China Bone Marrow Bank in 1992, only more than 14,000 patients have been successfully matched. According to the survey, a large number of volunteers in China will eventually choose to refuse to donate hematopoietic stem cells, which is closely related to the public's lack of understanding of hematopoietic stem cell donation. Unrelated volunteers can get less support from family members than related hematopoietic stem cell donors, which leads to their lower donation rate. Therefore, it is of great practical significance to study the family support system of unrelated hematopoietic stem cell donation volunteers.
我国有数百万急需造血干细胞移植的患者,但非亲缘造血干细胞的配型成功率仅为1/400~1/10000。自 1992 年中华骨髓库成立以来,配型成功的患者仅有 14000 多人。调查显示,我国大量志愿者最终会选择拒绝捐献造血干细胞,这与公众对造血干细胞捐献缺乏了解密切相关。与有亲缘关系的造血干细胞捐献者相比,无亲缘关系的志愿者从家庭成员那里得到的支持更少,这导致他们的捐献率更低。因此,研究非亲缘造血干细胞捐献志愿者的家庭支持系统具有重要的现实意义。
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引用次数: 0
The Effect of Preventive Care and Rehabilitation Nursing on Elderly Hypertension 预防护理和康复护理对老年高血压的影响
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2307
Yuanyuan He
Objective: To improve the effectiveness of elderly hypertension care, this research applied preventive care and rehabilitation nursing in clinical nursing to clarify their impact on elderly hypertension. Methods: A total of 95 elderly hypertensive patients who received diagnosis and treatment in the hospital during the period of January 2023 to December 2023 were analyzed. They were divided into a control group (49 cases) and an observation group (46 cases) in order of diagnosis and treatment. The patients in the control group were implemented conventional care methods, and the patients in the observation group using preventive care and rehabilitation nursing, the intervention effect between the two groups were analyzed. Results: Compared with the control group, in terms of clinical indicators and blood pressure and blood lipids, the observation group had lower values (P<0.05). In terms of healthy behavior, the observation group had higher values (P<0.05). Conclusion: Implementing preventive care and rehabilitation nursing in clinical nursing can have a positive impact on elderly patients with hypertension, which is beneficial for stabilizing clinical indicators, blood pressure indicators, blood lipid indicators, thus improving patients’ health behavior.
摘 要为提高老年高血压护理效果,本研究将预防护理和康复护理应用于临床护理中,明确其对老年高血压的影响。方法分析 2023 年 1 月至 2023 年 12 月期间在该院接受诊治的 95 例老年高血压患者。按照诊断和治疗顺序分为对照组(49 例)和观察组(46 例)。对照组患者实施常规护理方法,观察组患者采用预防护理和康复护理,分析两组患者的干预效果。结果与对照组相比,观察组在临床指标、血压血脂等方面的数值均低于对照组(P<0.05)。在健康行为方面,观察组的数值更高(P<0.05)。结论在临床护理中实施预防护理与康复护理,可对老年高血压患者产生积极影响,有利于稳定患者的临床指标、血压指标、血脂指标,从而改善患者的健康行为。
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引用次数: 0
Treatment of 52 Cases of Hypospadias by Longitudinal Section of Urethral Plate and Coiled Tube Urethroplasty 通过尿道板纵切面和螺旋管尿道成形术治疗 52 例尿道下裂病例
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2326
Guoqing Yu
Objective: To investigate the indications and some problems in the treatment of hypospadias by longitudinal section of urethral plate and coiled tube urethroplasty. Methods: All the children were treated with longitudinal urethral plate section and coiled tube urethroplasty. Results: The penis of all the children showed the appearance after circumcision, with normal erectile function, urethral opening in the right position of the head of the penis, postoperative urethral fistula in 4 cases, urethral stenosis in 3 cases, ventral swollen penis in 5 cases, slight torsion of the penis in 2 cases, and slight downward curvature of the penis in 1 case. Discussion: For distal and middle types of hypospadias with low penile flexion and well-developed urethral plates, longitudinal section urethral plate incision urethral tube urethroplasty has good surgical effect, short operation time and fewer postoperative complications. It is a commonly used surgical method at present.
目的探讨尿道板纵切和盘管尿道成形术治疗尿道下裂的适应症和一些问题。方法:所有患儿均接受尿道板纵切和盘管尿道成形术治疗。结果:所有患儿的阴茎均表现为包皮环切术后的外观,勃起功能正常,尿道开口位于阴茎头的正确位置,术后尿道瘘4例,尿道狭窄3例,阴茎腹侧肿胀5例,阴茎轻度扭转2例,阴茎轻度下弯1例。讨论对于阴茎屈曲度低、尿道板发育良好的中远端尿道下裂,纵切段尿道板切开尿道管尿道成形术具有手术效果好、手术时间短、术后并发症少等优点。是目前常用的手术方法。
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引用次数: 0
Construction of an Electrochemical Molecularly Imprinted Sensor Based on L-carnitine Doped Polypyrrole for Vibrio Parahaemolyticus Detection 构建基于掺杂左旋肉碱的聚吡咯的电化学分子印迹传感器以检测副溶血性弧菌
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2317
Jie Liu
This study addresses the pressing need for rapid detection of pathogenic microorganisms by designing and fabricating an L-carnitine-doped polypyrrole (L-CN/PPy) electrochemical molecularly imprinted sensor, with Vibrio parahaemolyticus as the model target. Employing L-carnitine as a dual-functional dopant and auxiliary recognition element in the electropolymerization process, the sensor not only enhances the conductive properties of polypyrrole but also significantly improves its specific recognition capability towards the target bacteria. The sensor preparation encompasses the electrochemical polymerization of L-CN/PPy composite material, immobilization and elution of template bacteria, followed by bacterial recognition and detection steps. Through systematic optimization of L-CN concentration, polymerization conditions, eluent composition, elution time, and operational parameters, the sensor's performance is maximized. Experimental results confirm the sensor's efficacy in rapidly completing template bacteria elution within just 30 minutes and achieving efficient recognition of Vibrio parahaemolyticus within 20 minutes, demonstrating high sensitivity and selectivity. Moreover, the straightforward and rapid construction method of the sensor introduces a novel technological strategy for practical microbial detection applications, highlighting extensive application prospects.
本研究以副溶血性弧菌为模型目标,设计并制造了一种掺杂左旋肉碱的聚吡咯(L-CN/PPy)电化学分子印迹传感器,从而满足了快速检测病原微生物的迫切需要。该传感器在电聚合过程中使用左旋肉碱作为双功能掺杂剂和辅助识别元素,不仅增强了聚吡咯的导电性能,还显著提高了其对目标细菌的特异性识别能力。传感器的制备包括 L-CN/PPy 复合材料的电化学聚合、模板细菌的固定和洗脱,以及随后的细菌识别和检测步骤。通过系统优化 L-CN 浓度、聚合条件、洗脱液成分、洗脱时间和操作参数,传感器的性能得以最大化。实验结果证实,该传感器能在短短 30 分钟内快速完成模板细菌的洗脱,并在 20 分钟内高效识别副溶血性弧菌,表现出极高的灵敏度和选择性。此外,该传感器的构建方法简单快捷,为实际微生物检测应用引入了一种新的技术策略,具有广泛的应用前景。
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引用次数: 0
Comparison of Long-term Efficacy of Domestic TAVR vs. Corevalve 国内 TAVR 与 Corevalve 的长期疗效比较
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2325
Menglun Zhou, Hengjin Dong
Aim: To assess the long-term effects of domestic valves and compare them with similar products to demonstrate non-inferiority and provide guidance for valve selection in severe aortic stenosis patients. Methods: The study comprised two parts: evaluating the long-term effects of domestic valves through follow-up data, and conducting a meta-analysis to assess the long-term efficacy of Corevalve. Results: Both valves showed high cumulative all-cause mortality and cardiac mortality rates at 5 years post-surgery, with statistically significant differences. There were also significant differences in the cumulative incidence rates of new pacemaker implantation and cardiac rehospitalization. Stroke and myocardial infarction event rates within 5 years were both below 10%, with no statistically significant differences. Conclusion: Domestic valves demonstrated favorable long-term effects, performing comparably or even superior to Corevalve in certain aspects.
目的:评估国产瓣膜的长期效果,并与同类产品进行比较,以证明其无劣势,并为重度主动脉瓣狭窄患者的瓣膜选择提供指导。研究方法:研究包括两部分:通过随访数据评估国产瓣膜的长期效果,以及进行荟萃分析评估 Corevalve 的长期疗效。研究结果两种瓣膜在术后 5 年的累积全因死亡率和心脏死亡率都很高,差异有统计学意义。新植入起搏器和心脏再住院的累积发生率也有明显差异。5 年内中风和心肌梗死事件发生率均低于 10%,差异无统计学意义。结论:国产瓣膜具有良好的长期效果,在某些方面的表现与Corevalve不相上下,甚至更胜一筹。
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引用次数: 0
Research on the Monitoring of Physiological Indexes of Freestyle Skiers before and after Competition 自由式滑雪运动员赛前赛后生理指标监测研究
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2310
Yanhong Wang
In order to understand the physiological characteristics of freestyle skiers before and after the competition and the alteration in their physical functions, a series of physiological indexes related to sports and health of freestyle skiers before and after the competition were examined in this study. 12 excellent athletes aged 9-18 years-old preparing for the 2022 Winter Olympic Games in the Hebei Provincial ski team were included. It was found that: 1. The average red blood cell volume, red blood cell distribution width, platelet distribution width, levels of glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, high-density lipoprotein cholesterol and creatine sarcosidase in the athletes were significantly reduced after the competition. Glucose level in the athletes increased significantly after the competition. 2. The physiological indexes, such as the levels of urea, lipoprotein (a), creatine sarcosidase, testosterone and the ratio of testosterone to cortisol, are significantly different between the athletes of different genders before or after the competition; 3. The physiological indexes such as platelet count, platelet distribution width, the levels of glutamic oxaloacetic transaminase, cortisol and the ratio of testosterone to cortisol of skiers are significantly different between the athletes of younger and the elder age before or after the competition. It guides us to monitor the state and alterations of skiers according to the change patterns of these physiological indicators, so as to guide the exercise intensity and rehabilitation training of skiers.
为了解自由式滑雪运动员赛前赛后的生理特点及其身体机能的变化,本研究对自由式滑雪运动员赛前赛后一系列与运动和健康相关的生理指标进行了检测。研究对象包括河北省滑雪队 12 名备战 2022 年冬奥会的 9-18 岁优秀运动员。研究发现1.运动员的平均红细胞体积、红细胞分布宽度、血小板分布宽度、谷丙转氨酶、谷草转氨酶、高密度脂蛋白胆固醇和肌氨酸肌苷酶水平在赛后明显下降。运动员的葡萄糖水平在赛后明显升高。2.2.不同性别运动员的尿素、脂蛋白(a)、肌酸肉毒酶、睾酮及睾酮与皮质醇的比值等生理指标在赛前或赛后均有明显差异;3.滑雪运动员的血小板计数、血小板分布宽度、谷草转氨酶、皮质醇及睾酮与皮质醇的比值等生理指标在赛前或赛后均有明显差异。根据这些生理指标的变化规律,指导我们监测滑雪运动员的状态和变化,从而指导滑雪运动员的运动强度和康复训练。
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引用次数: 0
Primary Presacral Neuroendocrine Tumors Presented by Lumbosacral Pain: a Case Report 以腰骶部疼痛为特征的原发性骶前神经内分泌肿瘤:病例报告
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2329
Xinzhi Wang, Xiaofen Ma
Primary presacral neuroendocrine tumors (NETs) are exceedingly rare and often present with extensive metastases, posing significant challenges for clinical management. We report a case of a presacral neuroendocrine tumor in a 68-year-old male who presented with lumbosacral pain. Enhanced MRI revealed a soft tissue mass at the sacrococcygeal region, while whole-body enhanced 18F-PET/CT identified small intratumoral vessels and involvement of the adjacent rectal posterior wall, mesorectal fascia, presacral fascia, and sacrococcygeal bones, accompanied by multiple lymph node metastases and widespread metastases to the lungs, liver, and bones. A CT-guided biopsy confirmed the diagnosis of a grade 2 (G2) neuroendocrine tumor. Given the tumor's extensive metastasis and aggressive nature, surgical intervention was deemed unsuitable, and the patient was treated with sulfatinib. Sulfatinib shows significant potential in managing advanced neuroendocrine tumors, providing an effective therapeutic option for patients with such complex and high-risk conditions.
原发性骶前神经内分泌肿瘤(NET)极为罕见,而且常常伴有广泛转移,给临床治疗带来了巨大挑战。我们报告了一例骶前神经内分泌肿瘤病例,患者为一名 68 岁男性,因腰骶部疼痛就诊。增强 MRI 显示骶尾部有一软组织肿块,而全身增强 18F-PET/CT 发现瘤内血管细小,邻近的直肠后壁、直肠间筋膜、骶前筋膜和骶尾部骨骼受累,伴有多处淋巴结转移以及肺、肝和骨骼的广泛转移。CT 引导下的活检确诊为 2 级(G2)神经内分泌肿瘤。鉴于肿瘤的广泛转移和侵袭性,手术治疗被认为并不合适,因此患者接受了磺拉替尼治疗。舒伐替尼在治疗晚期神经内分泌肿瘤方面显示出了巨大的潜力,为患有此类复杂和高风险疾病的患者提供了有效的治疗选择。
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引用次数: 0
Orthopedic Image Segmentation and Recognition Based on Deep Neural Networks 基于深度神经网络的骨科图像分割与识别
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2332
Kaiyang Zhang
In the field of medicine, especially orthopedics, accurate diagnosis is crucial. However, due to the uneven distribution of medical resources and the continuous growth of patient numbers, the diagnostic efficiency of hospitals has been significantly affected, and the problems of misdiagnosis and missed diagnosis are becoming increasingly prominent. To address these issues, this study explores a deep neural network-based orthopedic image segmentation and recognition model, aiming to improve the accuracy and efficiency of diagnosis. Firstly, we use U-Net neural network for segmentation training of orthopedic images in order to extract detailed features from the images.
在医学领域,尤其是骨科领域,准确的诊断至关重要。然而,由于医疗资源分配不均和患者人数的持续增长,医院的诊断效率受到很大影响,误诊和漏诊问题日益突出。针对这些问题,本研究探索了一种基于深度神经网络的骨科图像分割与识别模型,旨在提高诊断的准确性和效率。首先,我们使用 U-Net 神经网络对骨科图像进行分割训练,以提取图像中的细节特征。
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引用次数: 0
Application Analysis of Biodegradable Polymer Materials in Food Packaging 生物降解聚合物材料在食品包装中的应用分析
Pub Date : 2024-07-05 DOI: 10.32629/jcmr.v5i2.2333
Lijie Qiao
With the rapid development of biotechnology, the society pays more attention than in the past to the production and development of environmental protection. Choosing materials has always been a more important part of environmental protection work, among them, the degradable polymer materials are also professional research topics, it can be self-degradation under certain conditions, with far-reaching environmental protection value and social significance. Food packaging is a kind of carrier that plays a protective role in packaging, preservation and sales of food, the application of degradable polymer materials in food packaging can play a positive role in environmental protection, reducing environmental pollution and building an ecological society. In this paper, the active application of biodegradable polymer materials for food packaging is elaborated, hoping to provide theoretical reference.
随着生物技术的飞速发展,社会对环保的生产和发展比以往更加重视。材料的选择一直是环保工作中较为重要的一环,其中,可降解高分子材料也是专业的研究课题,它可以在一定条件下自我降解,具有深远的环保价值和社会意义。食品包装是一种载体,对食品的包装、保存和销售起到保护作用,可降解高分子材料在食品包装中的应用,对保护环境、减少环境污染、建设生态社会能起到积极作用。本文对可降解高分子材料在食品包装中的积极应用进行了阐述,希望能提供理论参考。
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引用次数: 0
期刊
Journal of Clinical Medicine Research
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