Potentials of Cannabis as versatile additive in consumer, industrial and medicinal products and green synthesis of nanoparticles: A systematic review

Abstract

The rapidly growing human population has upsurged the need for natural resources, endangering the environment and widening the gaps between availability and needs. The objective of this review was to compile the reported data on Cannabis- based food, beverage, cosmetics, textiles, composites and medicinal products with an emphasis on the regulatory framework and guidelines on Cannabis use, Cannabis- based green synthesis of NPs, and multiple ways of incorporating Cannabis with emphasis on critical factors to be considered while using Cannabis as an additive. We searched the data across scientific databases such as Google Scholar, SciELO, Medline, PubMed, Science Direct, Scopus, Web of Science, and some conference papers, books, dissertations and government reports. Almost 20 different Cannabis -based food and beverage products with enriched nutrition and 11 cosmetic products have been developed and reported with improved quality. The utilization of Cannabis for the development of textiles, composites and different kinds of medicines like Dronabinol (Marinol®), Nabilone, Sativex® or Nabiximols®, Cannapain® and Cannabis variety based preparations/products (on CBD and THC content basis) including Bedrocan, Bedica, Bedrolite, Bediol and Bedrobinol are available for human use. Various Cannabis NPs, including gold (AuNPs), silver (AgNPs), and selenium (SeNPs), are green synthesized with significant antioxidant, anti-inflammatory, and antimicrobial potentials. Because of the endless need for re-invention and the speedy evolution of the market, industries have found a state-of-the-art opportunity to develop various products and nanoparticles (NPs) using Cannabis as a versatile constituent, however, the efficacy of edible products depends upon the level of psychoactive THC present in Cannabis . Overall, the data provided here on Cannabis -based consumers, industrial and medicinal products, green synthesis of Cannabis NPs, and multiple ways of Cannabis incorporation in products considering possible challenges could add significant contributions to the global Cannabis research.