Prevalence of Malaria Infection among Patience Suspected of Typhoid Fever at the Bamenda and Bafoussam Regional Hospital

A. Asobochia, M. Dzeuta, F. Akoa, Ulrich Dama, J. Abanda, Désiré Tchoffo, Henri Kamga, V. Ndoungue
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Abstract

Purpose: Malaria is one of the febrile illnesses and the most common fatal disease in the world caused by one or more species of Plasmodium. Because malaria and typhoid fever usually display similar symptoms, malaria patients are likely to be suspected of typhoid fever, especially when they do not respond to the malaria first line medication. To determine the prevalence of malaria infection among patients suspected of typhoid fever in the Bamenda and Bafousam regional hospitals. Methodology: This study was a descriptive cross sectional study in which participants were recruited by convenience. The population for this study was volunteer patients suspected of typhoid fever by the respective hospital physicians. Blood samples were collected and Rapid Diagnostic Test was carried out, as well as thin and thick blood films. Data was analyzed using SPSS V20.0. Chi-square test was used to assess the association between results with a p-value of 0.05 considered significant at 95% confidence interval. Results: A total of 356 patients suspected of typhoid fever were contacted for the study of which 337 signed the consent form and took part in the study from the two targetted Regional Hospitals giving a participation rate of 94.66%. Among the participants, 195[57.9%] were from the Bamenda regional hospital while 142[42.1%] were from the Bafoussam regional hospital. Majority 65.9% of the participants were females recorded in both hospitals. An overall prevalence of 37.4% was recorded in both the Bafoussam and Bamenda regional hospital there was thus no statistical significant difference between the result gotten from the two Regional Hospitals [p=0.3]. The age group with the highest prevalence was that of 10-29 years. More than 90% of infections were caused by Plasmodium falciparum while about 3% of the infections were due to Plasmodium vivax. The prevalence of malaria infections in patients suspected of typhoid fever in the Bamenda and Bafoussam Regional Hospitals is 37.4%, and more women were infected than males. Unique Contribution to Theory, Practice and Policy:  We advocated that proper malaria investigation of suspected cases should be carried out before embarking into typhoid fever treatment. This study have saved as an eye opener to medical practitioners to test both typhoid and malaria for all patients presenting with such signs and symptoms.
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巴门达和巴富萨姆地区医院疑似伤寒患者的疟疾感染率
目的:疟疾是发热性疾病之一,也是世界上最常见的致命疾病,由一种或多种疟原虫引起。由于疟疾和伤寒通常表现出相似的症状,疟疾患者很可能被怀疑为伤寒,尤其是当他们对疟疾一线药物无反应时。目的:确定巴门达和巴富萨姆地区医院中疑似伤寒患者的疟疾感染率。研究方法:本研究是一项描述性横断面研究,通过方便的方式招募参与者。研究对象是医院医生怀疑为伤寒的自愿患者。研究人员采集了血液样本,进行了快速诊断测试,并拍摄了血液薄片和厚片。数据使用 SPSS V20.0 进行分析。采用卡方检验来评估结果之间的关联性,在 95% 的置信区间内,P 值为 0.05 即为显著。结果两家目标地区医院共联系了356名疑似伤寒患者参与研究,其中337人签署了同意书并参与了研究,参与率为94.66%。其中 195 人[57.9%]来自巴门达地区医院,142 人[42.1%]来自巴富萨姆地区医院。在两家医院中,65.9%的参与者为女性。巴富萨姆和巴门达地区医院的总患病率均为 37.4%,因此两家地区医院的结果在统计学上没有显著差异[P=0.3]。发病率最高的年龄组是 10-29 岁。90%以上的感染由恶性疟原虫引起,约3%的感染由间日疟原虫引起。在巴门达和巴富萨姆地区医院的伤寒疑似患者中,疟疾感染率为 37.4%,女性感染者多于男性。对理论、实践和政策的独特贡献: 我们主张,在开始伤寒治疗之前,应对疑似病例进行适当的疟疾调查。这项研究让医疗从业人员大开眼界,对所有出现此类体征和症状的患者同时进行伤寒和疟疾检测。
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