Effectiveness of organizational and legal measures and new practices to against HIV infection in the Novosibirsk region

D. V. Kapustin, L. Pozdnyakova, E. I. Krasnova, N. I. Khokhlova, A. K. Tsoi, N. I. Shulgina, Yu. A. Stashevskay
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Abstract

The purpose of the study: to study the effectiveness of organizational and legal measures and new practices to against HIV infection introduced in the Novosibirsk region in 2019–2022.Materials and methods. The study was conducted on the basis of the State Medical Institution of the NGO «City Infectious Clinical Hospital No. 1», a division of the Center for the Prevention and Control of AIDS.Results. By Order of the Ministry of Health of the Novosibirsk Region No. 3429 of 10/15/2019, mandatory HIV screening was provided for all hospitalized with unknown HIV status during the year, which significantly increased the coverage of HIV screening. In 2019–2022, an AIDS Center information system was introduced for all patients with HIV infection admitted to inpatient treatment: 6,938 notifications were sent to the AIDS Center. Of the 2,717 patients who required measures to increase the level of adherence and involvement in ART, 18.9% of patients resumed ART after the measures taken; 36.5% started taking ART for the first time. The order of the State Medical Institution of the Infectious Clinical Hospital № 247 «On the organization of family support in the department «Center for the Prevention and Control of AIDS» dated 02.08.2021 provides the principle of monitoring the whole family with one doctor, which improves the adherence of children and parents to ART. For 4 months of functioning of family support, the share of parents receiving ART and having a high commitment increased from 15.5% to 77.3%. Among 45 children who had a previously determined level of HIV RNA viral load on the background of ART, 20% (9 abs.) registered an undetectable level of viral load for 3 months, and 13.3% (6 abs.) – for 2 months.Conclusion. The organizational and legal measures implemented in 2019–2022 in the Novosibirsk region and new practices to combat HIV infection have shown high efficiency: the coverage of dispensary observation of patients with HIV infection increased from 79.3% to 86.5%, and the coverage of antiretroviral therapy – from 74.5% to 85.2%.
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新西伯利亚州预防艾滋病毒感染的组织措施、法律措施和新做法的有效性
研究目的:研究 2019-2022 年新西伯利亚州预防艾滋病毒感染的组织、法律措施和新做法的有效性。研究在非政府组织 "市第一传染病临床医院 "国家医疗机构(艾滋病预防与控制中心下属机构)的基础上进行。根据新西伯利亚州卫生部2019年10月15日第3429号命令,本年度对所有艾滋病毒感染状况不明的住院病人进行强制性艾滋病毒筛查,这大大提高了艾滋病毒筛查的覆盖率。2019-2022年,针对所有住院治疗的艾滋病毒感染者引入了艾滋病中心信息系统:向艾滋病中心发送了 6938 份通知。在需要采取措施提高抗逆转录病毒疗法依从性和参与程度的 2 717 名患者中,18.9%的患者在采取措施后恢复了抗逆转录病毒疗法;36.5%的患者首次开始服用抗逆转录病毒疗法。2021 年 8 月 2 日国家传染病临床医院第 247 号 "关于在'艾滋病预防和控制中心'部门组织家庭支持" 的命令规定了由一名医生对整个家庭进行监测的原则,这提高了儿童和父母坚持抗逆转录病毒疗法的程度。在家庭支助运作的 4 个月中,接受抗逆转录病毒疗法并做出高度承诺的父母比例从 15.5%增至 77.3%。在抗逆转录病毒疗法背景下,45 名儿童的艾滋病毒 RNA 病毒载量水平先前已确定,其中 20%(9 例)的病毒载量在 3 个月内检测不到,13.3%(6 例)的病毒载量在 2 个月内检测不到。新西伯利亚州 2019-2022 年实施的组织和法律措施以及抗击艾滋病毒感染的新做法显示出很高的效 率:对艾滋病毒感染者进行诊室观察的覆盖率从 79.3%增至 86.5%,抗逆转录病毒疗法的覆盖率从 74.5% 增至 85.2%。
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