Assessment of early outcome of coronary artery bypass grafting with and without mitral valve surgery in moderate ischemic mitral regurgitation: A multicenter comparative cohort study

Mohamed Abdelfatah Ali, Morsi A. Mohammed, H. Elayouty, M. A. Amr, Elsayed A Fayad
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Abstract

Background: Some experts believe that revascularization alone for moderate ischemic mitral regurgitation, due to improvements in global and regional left ventricular function and geometry after coronary artery bypass grafting (CABG), can decrease rates of mitral regurgitation, however, the value of adding mitral valve repair or not to the CABG surgery remains controversial. Aim: To compare the early peri-operative results of surgical management of moderate ischemic mitral regurgitation by revascularization alone versus revascularization plus mitral valve surgery. Patients and Methods: This prospective cohort comparative study was conducted at Suez Canal University Hospitals, and Suez Hospital for Health Insurance, Cardiac Surgery Department from January 2020 to January 2023. This study was conducted on 100 patients with IHD undergoing CABG with moderate ischemic mitral regurge attending our clinic in Suez Canal University Hospital and Cardiac Surgery Department in Suez Hospital for Health Insurance. Results: The New York Heart Association (NYHA) classification showed statistically significant difference between both groups ( P=0.008 ). Also, group I had a higher mean of left ventricular ejection fraction than group II with statistically insignificant differences ( P>0.05 ). Group I had significantly lower segmental wall-motion abnormalities than group II with statistically significant differences ( P=0.042 ). Also, the severity of mitral regurgitation was significantly lower among group I than group II ( P=0.028 ). Among group I, the severity of NYHA classification distribution showed a statistically significant decrease ( P<0.001 ). Conclusion: Moderate mitral regurgitation in patients undergoing isolated CABG adversely NYHA functional class and mitral regurgitation does not reliably improve after CABG alone.
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中度缺血性二尖瓣反流患者接受冠状动脉旁路移植术和不接受二尖瓣手术的早期疗效评估:多中心队列比较研究
背景:一些专家认为,由于冠状动脉旁路移植术(CABG)后整体和区域左心室功能和几何形状的改善,单纯血管再通术治疗中度缺血性二尖瓣反流可降低二尖瓣反流率,但在CABG手术中是否增加二尖瓣修复术的价值仍存在争议。目的:比较单纯血管重建与血管重建加二尖瓣手术治疗中度缺血性二尖瓣反流的早期围手术期效果。患者和方法:这项前瞻性队列比较研究于 2020 年 1 月至 2023 年 1 月在苏伊士运河大学医院和苏伊士医疗保险医院心脏外科进行。研究对象为 100 名接受 CABG 手术并伴有中度缺血性二尖瓣返流的 IHD 患者,他们分别在苏伊士运河大学医院和苏伊士健康保险医院心脏外科就诊。结果:纽约心脏协会(NYHA)分级显示,两组之间存在显著统计学差异(P=0.008)。此外,I 组的左心室射血分数平均值高于 II 组,但差异无统计学意义(P>0.05)。Ⅰ组的节段室壁运动异常明显低于Ⅱ组,差异无统计学意义(P=0.042)。此外,Ⅰ组的二尖瓣反流严重程度也明显低于Ⅱ组(P=0.028)。在 I 组中,NYHA 分级分布的严重程度有统计学意义的下降 ( P<0.001 )。结论接受孤立 CABG 的患者中度二尖瓣反流会对 NYHA 功能分级产生不利影响,且单独接受 CABG 后二尖瓣反流不会得到可靠改善。
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