首页 > 最新文献

The Egyptian Journal of Surgery最新文献

英文 中文
Study of the value of core biopsy for establishing tissue diagnosis compared to excisional biopsy in enlarged cervical lymph nodes 宫颈淋巴结肿大的组织诊断中核心活检与切除活检的价值比较研究
Pub Date : 2024-07-06 DOI: 10.21608/ejsur.2024.357124
Karim N.F. Mahmoud, Ahmed A.E.A. ء A.E.A. Elmged, Omnia A. Seyam, B. Ayoub, A. Elghandour
Background: Core tissue biopsy involves sampling tissue with a wider gauge than is used for fine-needle aspiration cytology. Core biopsy may be used as an alternative to surgical excisional lymph node biopsy as it would provide less risk to the patients as regards wound infection, scar, bleeding, accessory nerve injury, and the risk of complications of general anesthesia. The aim of this work was to assess the accuracy, specificity, and sensitivity of core biopsy in establishing tissue diagnosis of enlarged cervical lymph nodes. Patients and Methods: This prospective study was carried out on 100 patients, 50 for core biopsy and 50 for excisional biopsy, aged more than 18 years old, both sexes, with cervical lymphadenopathy indicated for ultrasonography (US)- guided core biopsy. Results: Based on our study, the diagnostic rate of core needle biopsy (CNB) is 53 cores and 10% of them need an excisional biopsy. 95% of lymphoma patients were diagnosed by core biopsies. Every CNB patient underwent hydrodissection and got a safe puncture distance. In cervical lymphadenopathy diagnosis, CNB had 89% sensitivity, 100% specificity, 100% positive predictive value, and 66% negative predictive value. Conclusion: Performing core samples of cervical lymph nodes in cases of cervical lymphadenopathy, especially US-guided core biopsy, can be beneficial in achieving a diagnosis as well as decreasing the need for excisional biopsies performed under general anesthesia.
背景:核心组织活检是指用比细针穿刺细胞学检查更宽的针管采集组织样本。核心组织活检可作为手术切除淋巴结活检的替代方法,因为这种方法在伤口感染、疤痕、出血、附属神经损伤以及全身麻醉并发症等方面对患者造成的风险较小。这项研究旨在评估核心活检在确定宫颈淋巴结肿大组织诊断方面的准确性、特异性和敏感性。患者和方法:这项前瞻性研究的对象是 100 名年龄在 18 岁以上、有超声波(US)引导核心活检指征的宫颈淋巴结肿大患者,其中 50 名接受核心活检,50 名接受切除活检。结果根据我们的研究,核心针活检(CNB)的诊断率为 53%,其中 10%需要进行切除活检。95%的淋巴瘤患者通过核心活检确诊。每位 CNB 患者都接受了水压切片检查,并获得了安全的穿刺距离。在宫颈淋巴结病诊断中,CNB 的敏感性为 89%,特异性为 100%,阳性预测值为 100%,阴性预测值为 66%。结论在宫颈淋巴结病病例中进行宫颈淋巴结核心样本检查,尤其是 US 引导下的核心活检,有助于获得诊断结果,并减少在全身麻醉下进行切除活检的需要。
{"title":"Study of the value of core biopsy for establishing tissue diagnosis compared to excisional biopsy in enlarged cervical lymph nodes","authors":"Karim N.F. Mahmoud, Ahmed A.E.A. ء A.E.A. Elmged, Omnia A. Seyam, B. Ayoub, A. Elghandour","doi":"10.21608/ejsur.2024.357124","DOIUrl":"https://doi.org/10.21608/ejsur.2024.357124","url":null,"abstract":"Background: Core tissue biopsy involves sampling tissue with a wider gauge than is used for fine-needle aspiration cytology. Core biopsy may be used as an alternative to surgical excisional lymph node biopsy as it would provide less risk to the patients as regards wound infection, scar, bleeding, accessory nerve injury, and the risk of complications of general anesthesia. The aim of this work was to assess the accuracy, specificity, and sensitivity of core biopsy in establishing tissue diagnosis of enlarged cervical lymph nodes. Patients and Methods: This prospective study was carried out on 100 patients, 50 for core biopsy and 50 for excisional biopsy, aged more than 18 years old, both sexes, with cervical lymphadenopathy indicated for ultrasonography (US)- guided core biopsy. Results: Based on our study, the diagnostic rate of core needle biopsy (CNB) is 53 cores and 10% of them need an excisional biopsy. 95% of lymphoma patients were diagnosed by core biopsies. Every CNB patient underwent hydrodissection and got a safe puncture distance. In cervical lymphadenopathy diagnosis, CNB had 89% sensitivity, 100% specificity, 100% positive predictive value, and 66% negative predictive value. Conclusion: Performing core samples of cervical lymph nodes in cases of cervical lymphadenopathy, especially US-guided core biopsy, can be beneficial in achieving a diagnosis as well as decreasing the need for excisional biopsies performed under general anesthesia.","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141672011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic Toupet versus Nissen fundoplication for the treatment of gastroesophageal reflux disease: Randomized prospective study 腹腔镜下胃食管反流术与尼森胃底折叠术的对比:随机前瞻性研究
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.274542.1012
M. El sorogy, Mahmoud Haggag, A. Elghawalby, E. Hamdy, Rami Said
. ABSTRACT Objective: To compare laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication in terms of postoperative acid reflux control and postoperative complications, especially dysphagia and gas bloat on a short-term basis. Patients and Methods: This prospective randomized study included 50 patients with gastroesophageal reflux disease who presented at Gastrointestinal Surgical Center, Mansoura University, for antireflux surgery from August 2021 to August 2022. Results: The incidence of dysphagia was higher in the Nissen group than in Toupet in early postoperative follow-up (3 months) compared with the Toupet group ( P=0.008 ), but the incidence of dysphagia decreased among the Nissen group during follow-up periods while no incidence of dysphagia in Toupet group ( P=0.077 ). Regarding heartburn score, there was no statistically significance between the two groups Toupet and Nissen ( P=0.200 ) at early follow-up periods. However after 18-month postoperative, Nissen group showed better control of heartburn symptoms when compared to the Toupet group ( P=0.045 ). In the current study, according to quality of life after 1 year and patient satisfaction, there was no significant difference between the two procedures ( P=0.059 ). Conclusion: Nissen fundoplication shows a high incidence of dysphagia and gas bloat symptoms during early postoperative periods when compared with Toupet fundoplication, but this incidence decreases along follow-up periods. On the other hand, Nissen fundoplication shows better acid reflux control all over the follow-up periods
.ABSTRACT Objective:比较腹腔镜 Nissen 胃底折叠术和腹腔镜 Toupet 胃底折叠术在术后反酸控制和术后并发症(尤其是吞咽困难和气胀)方面的短期效果。患者和方法:这项前瞻性随机研究纳入了 2021 年 8 月至 2022 年 8 月期间在曼苏拉大学胃肠外科中心接受抗反流手术的 50 名胃食管反流病患者。手术结果在术后早期随访(3个月)中,尼森组吞咽困难发生率高于Toupet组(P=0.008),但在随访期间,尼森组吞咽困难发生率有所下降,而Toupet组无吞咽困难发生率(P=0.077)。在胃灼热评分方面,Toupet 和 Nissen 两组在早期随访期间没有统计学意义(P=0.200)。但术后18个月后,与Toupet组相比,Nissen组胃灼热症状得到了更好的控制(P=0.045)。在本研究中,根据一年后的生活质量和患者满意度,两种手术之间没有显著差异(P=0.059)。结论与图佩特胃底折叠术相比,尼森胃底折叠术在术后早期出现吞咽困难和气胀症状的几率较高,但随着随访时间的延长,这种几率会逐渐降低。另一方面,尼森胃底折叠术在整个随访期间能更好地控制胃酸反流。
{"title":"Laparoscopic Toupet versus Nissen fundoplication for the treatment of gastroesophageal reflux disease: Randomized prospective study","authors":"M. El sorogy, Mahmoud Haggag, A. Elghawalby, E. Hamdy, Rami Said","doi":"10.21608/ejsur.2024.274542.1012","DOIUrl":"https://doi.org/10.21608/ejsur.2024.274542.1012","url":null,"abstract":". ABSTRACT Objective: To compare laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication in terms of postoperative acid reflux control and postoperative complications, especially dysphagia and gas bloat on a short-term basis. Patients and Methods: This prospective randomized study included 50 patients with gastroesophageal reflux disease who presented at Gastrointestinal Surgical Center, Mansoura University, for antireflux surgery from August 2021 to August 2022. Results: The incidence of dysphagia was higher in the Nissen group than in Toupet in early postoperative follow-up (3 months) compared with the Toupet group ( P=0.008 ), but the incidence of dysphagia decreased among the Nissen group during follow-up periods while no incidence of dysphagia in Toupet group ( P=0.077 ). Regarding heartburn score, there was no statistically significance between the two groups Toupet and Nissen ( P=0.200 ) at early follow-up periods. However after 18-month postoperative, Nissen group showed better control of heartburn symptoms when compared to the Toupet group ( P=0.045 ). In the current study, according to quality of life after 1 year and patient satisfaction, there was no significant difference between the two procedures ( P=0.059 ). Conclusion: Nissen fundoplication shows a high incidence of dysphagia and gas bloat symptoms during early postoperative periods when compared with Toupet fundoplication, but this incidence decreases along follow-up periods. On the other hand, Nissen fundoplication shows better acid reflux control all over the follow-up periods","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141713989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospective comparative study between anterior approach and conventional approach right formal hepatic resection for large hepatocellular carcinom 大肝细胞癌右侧正规肝切除术前路与常规路的前瞻性比较研究
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.287458.1065
Zeinab Hassan Ibrahim Awad, Mahmoud T. Rayan, Hesham Hassan Wagdy, H. S. Saber
Background: A study is carried out to assess the possible advantages of operative and postoperative outcomes of the anterior approach (AA) over the conventional approach (CA) in major right hepatectomy for large hepatocellular carcinoma (HCC). Patients and Methods: A prospective randomized controlled study was performed on 50 patients who had a large (≥5 cm) right lobe of the liver HCC and underwent curative right formal hepatectomy during a 28-month period. The patients were randomized to undergo resection of the tumor using the anterior approach technique (AA group, n=25) or the conventional approach technique (CA group, n=25). The CA involves initial complete mobilization of the right liver followed by extrahepatic vascular control then hepatic parenchymatous dissection is performed. AA consists of initial vascular inflow control and parenchymal transection before mobilization of the right lobe. Results: There was no significant difference between the two groups as regards clinical, laboratory, and pathological parameters. The operative results showed a significant blood loss in the CA group in comparison to the AA group. The AA group had better disease-free survival and overall survival than the CA group. Conclusion: The anterior approach is the recommended technique for right formal hepatectomy for large HCC as it results in improved operative and survival outcomes of the patients.
背景:本研究旨在评估在大肝细胞癌(HCC)右肝大部切除术中,前路(AA)与传统方法(CA)相比在手术和术后效果方面可能具有的优势。患者和方法:一项前瞻性随机对照研究针对50名肝脏右叶巨大(≥5厘米)HCC患者,他们在28个月内接受了治愈性右侧正规肝切除术。患者被随机分为前入路技术(AA 组,25 人)和常规入路技术(CA 组,25 人)两组。CA包括首先完全移动右肝,然后控制肝外血管,再进行肝实质切除。AA包括最初的血管流入控制和实质横断,然后再移动右肝叶。结果:两组患者的临床、实验室和病理参数无明显差异。手术结果显示,与 AA 组相比,CA 组的失血量更大。AA 组的无病生存率和总生存率均优于 CA 组。结论:前路是治疗大块肝癌的右正规肝切除术的推荐技术,因为它能改善患者的手术效果和生存率。
{"title":"Prospective comparative study between anterior approach and conventional approach right formal hepatic resection for large hepatocellular carcinom","authors":"Zeinab Hassan Ibrahim Awad, Mahmoud T. Rayan, Hesham Hassan Wagdy, H. S. Saber","doi":"10.21608/ejsur.2024.287458.1065","DOIUrl":"https://doi.org/10.21608/ejsur.2024.287458.1065","url":null,"abstract":"Background: A study is carried out to assess the possible advantages of operative and postoperative outcomes of the anterior approach (AA) over the conventional approach (CA) in major right hepatectomy for large hepatocellular carcinoma (HCC). Patients and Methods: A prospective randomized controlled study was performed on 50 patients who had a large (≥5 cm) right lobe of the liver HCC and underwent curative right formal hepatectomy during a 28-month period. The patients were randomized to undergo resection of the tumor using the anterior approach technique (AA group, n=25) or the conventional approach technique (CA group, n=25). The CA involves initial complete mobilization of the right liver followed by extrahepatic vascular control then hepatic parenchymatous dissection is performed. AA consists of initial vascular inflow control and parenchymal transection before mobilization of the right lobe. Results: There was no significant difference between the two groups as regards clinical, laboratory, and pathological parameters. The operative results showed a significant blood loss in the CA group in comparison to the AA group. The AA group had better disease-free survival and overall survival than the CA group. Conclusion: The anterior approach is the recommended technique for right formal hepatectomy for large HCC as it results in improved operative and survival outcomes of the patients.","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141706529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study between one stage and two-stages superficialization of brachio-basilic arteriovenous fistula as a hemodialysis access procedure 作为血液透析通路手术的一期和二期肱-基底动静脉瘘表层化手术比较研究
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357131
Ahmed M. El-Mahdi, Hatem K. Elgohary, Karim R. Sallam, Mohamed M. S. Ahmed, Ahmed M. A. Elsayed
Background: The best technique for creating brachiobasilic arteriovenous fistulas (BBAVFs) is still up for debate. Because of this, the purpose of this study was to examine the patencies, primary failure rates, and complication rates of brachiaobasilic arteriovenous fistulas formed using the one-stage and two-stage superficialization techniques. Patients and Methods: In order to compare one stage and two-stage superficialization of brachiobasilic arteriovenous fistula, a prospective, randomized controlled clinical trial including 38 patients undergoing brachiobasilic arteriovenous fistula operations for end-stage renal disease was carried out. Two groups of patients were created using basic randomization. Patients in Group I underwent a single step of superficialization for their brachiobasilic arteriovenous fistula, whereas patients in Group II got a two-stage superficialization procedure. Results: Patients with two-stage BBAVF had a substantially longer fistula maturation period than patients with one-stage BBAVF. However, patients with two-stage BBAVF also had considerably greater fistula flow rate and primary functional patency when compared to patients with one-stage BBAVF. In terms of the complications in both groups, patients with one-stage BBAVF had a considerably greater incidence of thrombosis and post-operative hematoma than patients with two-stage BBAVF. However, there was no discermible difference in the two groups’ incidence of infection, steal syndrome, hematoma, or pseudoaneurysm. Conclusion:
背景:创建肱骨动静脉瘘(BBAVF)的最佳技术仍有争议。正因为如此,本研究的目的是检查使用一步法和两步法表层化技术形成的肱动脉动静脉瘘的通畅率、初次失败率和并发症发生率。患者和方法:为了比较一段式和两段式动静脉瘘表层化技术,我们开展了一项前瞻性随机对照临床试验,其中包括 38 名因终末期肾病接受动静脉瘘手术的患者。试验采用基本随机法将患者分为两组。I 组患者的肱动脉动静脉瘘只接受了一步表浅术,而 II 组患者则接受了两步表浅术。结果两段式肱动脉动静脉瘘患者的瘘管成熟期远远长于一段式肱动脉动静脉瘘患者。不过,与一期 BBAVF 患者相比,二期 BBAVF 患者的瘘管流速和主要功能通畅率也要高得多。就两组患者的并发症而言,一段式 BBAVF 患者的血栓形成和术后血肿发生率大大高于二段式 BBAVF 患者。不过,两组患者的感染、盗血综合征、血肿或假性动脉瘤发生率没有明显差异。结论
{"title":"Comparative study between one stage and two-stages superficialization of brachio-basilic arteriovenous fistula as a hemodialysis access procedure","authors":"Ahmed M. El-Mahdi, Hatem K. Elgohary, Karim R. Sallam, Mohamed M. S. Ahmed, Ahmed M. A. Elsayed","doi":"10.21608/ejsur.2024.357131","DOIUrl":"https://doi.org/10.21608/ejsur.2024.357131","url":null,"abstract":"Background: The best technique for creating brachiobasilic arteriovenous fistulas (BBAVFs) is still up for debate. Because of this, the purpose of this study was to examine the patencies, primary failure rates, and complication rates of brachiaobasilic arteriovenous fistulas formed using the one-stage and two-stage superficialization techniques. Patients and Methods: In order to compare one stage and two-stage superficialization of brachiobasilic arteriovenous fistula, a prospective, randomized controlled clinical trial including 38 patients undergoing brachiobasilic arteriovenous fistula operations for end-stage renal disease was carried out. Two groups of patients were created using basic randomization. Patients in Group I underwent a single step of superficialization for their brachiobasilic arteriovenous fistula, whereas patients in Group II got a two-stage superficialization procedure. Results: Patients with two-stage BBAVF had a substantially longer fistula maturation period than patients with one-stage BBAVF. However, patients with two-stage BBAVF also had considerably greater fistula flow rate and primary functional patency when compared to patients with one-stage BBAVF. In terms of the complications in both groups, patients with one-stage BBAVF had a considerably greater incidence of thrombosis and post-operative hematoma than patients with two-stage BBAVF. However, there was no discermible difference in the two groups’ incidence of infection, steal syndrome, hematoma, or pseudoaneurysm. Conclusion:","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141700276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of aortic valve prosthesis-patient mismatch on left ventricular mass regression 主动脉瓣假体与患者不匹配对左心室质量回归的影响
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.274048.1003
Amr A. Ibrahim, Mohamed Attia, Ayman Ammar, Tamer Hikal
Background: Aortic valve replacement (AVR) aim to allow left ventricular mass (LVM) regression by relieving valve stenosis and lowering LV pressure. When the effective orifice area (EOA) of the prosthetic valve that has been placed is too small in comparison to the body surface area, it is known as valve prosthesis-patient mismatch (PPM). Thus, the aim of this investigation is to determine if PPM and the degree of LVM regression following AVR are related. Patients and Methods: The study was a prospective cohort study of 100 patients with isolated aortic stenosis who underwent AVR for 2 years and were placed in two groups (50 patients in each group); group A consisted of patients with no PPM [indexed effective orifice area (IEOA) > 0.85 cm 2 /m 2 ], and group B consisting of patients with PPM (IEOA ≤ 0.85 cm 2 /m 2 ). The main outcomes of interest are type, size, EOA, and IEOA of the prosthetic aortic valve used, follow-up echocardiography after 12 months including gradient across the prosthetic valve, LVM, and LVM regression. Results: Significant differences were observed between the two groups. In the PPM group, there were fewer reductions in both mean and peak aortic valve gradients compared to the no PPM group. LVM showed a marked absolute regression in the no PPM group (87.0 ± 30.6 g) compared to the PPM group (39.1± 15.9 g, P < 0.001). Conclusion: This study shows that PPM may hamper the regression of LVM after AVR.
背景:主动脉瓣置换术(AVR)的目的是通过缓解瓣膜狭窄和降低左心室压力来实现左心室质量(LVM)的恢复。如果置入的人工瓣膜的有效孔面积(EOA)与体表面积相比过小,则称为人工瓣膜-患者不匹配(PPM)。因此,本研究旨在确定 PPM 与 AVR 术后 LVM 回归程度是否相关。患者和方法:该研究是一项前瞻性队列研究,100 名孤立性主动脉瓣狭窄患者接受了为期 2 年的房室成形术,并被分为两组(每组 50 名患者):A 组包括无 PPM 的患者[指数化有效孔面积 (IEOA) > 0.85 cm 2 /m 2 ],B 组包括有 PPM 的患者(IEOA ≤ 0.85 cm 2 /m 2 )。主要研究结果包括所用人工主动脉瓣的类型、大小、EOA 和 IEOA,12 个月后的随访超声心动图,包括人工瓣膜的梯度、LVM 和 LVM 回归。结果两组之间存在显著差异。与无 PPM 组相比,PPM 组主动脉瓣平均梯度和峰值梯度的降低幅度较小。与 PPM 组(39.1± 15.9 g,P < 0.001)相比,无 PPM 组(87.0± 30.6 g)的 LVM 绝对值明显下降。结论:本研究表明,PPM 可能会阻碍 AVR 后 LVM 的恢复。
{"title":"Impact of aortic valve prosthesis-patient mismatch on left ventricular mass regression","authors":"Amr A. Ibrahim, Mohamed Attia, Ayman Ammar, Tamer Hikal","doi":"10.21608/ejsur.2024.274048.1003","DOIUrl":"https://doi.org/10.21608/ejsur.2024.274048.1003","url":null,"abstract":"Background: Aortic valve replacement (AVR) aim to allow left ventricular mass (LVM) regression by relieving valve stenosis and lowering LV pressure. When the effective orifice area (EOA) of the prosthetic valve that has been placed is too small in comparison to the body surface area, it is known as valve prosthesis-patient mismatch (PPM). Thus, the aim of this investigation is to determine if PPM and the degree of LVM regression following AVR are related. Patients and Methods: The study was a prospective cohort study of 100 patients with isolated aortic stenosis who underwent AVR for 2 years and were placed in two groups (50 patients in each group); group A consisted of patients with no PPM [indexed effective orifice area (IEOA) > 0.85 cm 2 /m 2 ], and group B consisting of patients with PPM (IEOA ≤ 0.85 cm 2 /m 2 ). The main outcomes of interest are type, size, EOA, and IEOA of the prosthetic aortic valve used, follow-up echocardiography after 12 months including gradient across the prosthetic valve, LVM, and LVM regression. Results: Significant differences were observed between the two groups. In the PPM group, there were fewer reductions in both mean and peak aortic valve gradients compared to the no PPM group. LVM showed a marked absolute regression in the no PPM group (87.0 ± 30.6 g) compared to the PPM group (39.1± 15.9 g, P < 0.001). Conclusion: This study shows that PPM may hamper the regression of LVM after AVR.","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141701218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single anastomosis sleeve jejunal bypass versus one anastomosis gastric bypass in treatment of obesity and metabolic diseases: A randomized controlled trial 单吻合袖带空肠旁路术与单吻合胃旁路术在治疗肥胖和代谢性疾病方面的比较:随机对照试验
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357109
Y. K. S. M. Salem, S. A. A. Maaty, K. S. Abdelsamee, Ahmed M. Farrag
Introduction: Bariatric surgeries are an effective treatment for morbid obesity and its associated co-morbidities including type 2 diabetes mellitus, hypertension (HTN), and dyslipidemia. Single anastomosis sleeve jejunal (SASJ) has not been well studied in the literature or compared with other bariatric surgeries. We aim to compare one anastomosis gastric bypass (OAGB) to SASJ in terms of reduction in BMI, resolution of co-morbidities, postoperative complications, and nutritional status. Patients and Methods: A randomized clinical trial of patients undergoing either OAGB or SASJ at 1:1 ratio for treatment of morbid obesity. Participants were enrolled since April 2022 and were followed for at least 12 months at bariatric surgery department at Ain Shams University Hospital, a tertiary care center. Inclusion criteria for participant’s enrollment were age between 18 and 60 years old and BMI greater than or equal to 40 or BMI 35–40 with obesity-related comorbidities. Patients were excluded if preoperative upper gastrointestinal endoscopy showed GERD class C or Barrett’s esophagus, previous upper gastrointestinal tract surgery or liver cirrhosis, on oral steroid therapy, previous bariatric surgery, contraindications for abdominal insufflation as those with severe cardiovascular or severe restrictive respiratory diseases, Not fit for general anesthesia, significant abdominal ventral hernia, major psychiatric illness, and pregnant. Primary outcome involves weight loss, BMI loss, total weight loss %, and excess weight loss (EWL%). Secondary outcomes include resolution of comorbidities, biliary reflux, postoperative complications, readmissions, reoperations, and nutritional status. Results: Since April 2022, 68 patients have been enrolled into the study. The mean age, weight, and BMI of the entire cohort are 38.32±10.08 years old, 124.72±18.75 kg, and 43.97±5.47 kg/m 2 . A higher number of patients had DM and/or HTN in SASJ (38.2% DM, 47.1% HTN) compared with OAGB. Comparison between both groups showed no significant statistical difference in postoperative complications ( P=0.135 ), readmissions ( P=1 ), reoperations ( P=0.555 ), and bile reflux ( P=0.09 ). Both SASJ and OAGB groups had comparable postoperative weight loss, BMI, EWL % at 6 and 12 months of follow-up, however, OAGB had significantly higher total weight loss % at 6 months only. SASJ patients had a significantly higher rate of resolution from DM compared with OAGB patients ( P=0.012 ). No significant difference between both groups in the resolution of HTN ( P=0.07 ) and dyslipidemia ( P=0.03 ). Patients who had OAGB had a higher rate of gallstones postoperatively compared with SASJ patients ( P=0.001 ). None of the patients had anemia, hypoalbuminemia, or iron deficiency. Regarding vitamin D and calcium, no significant differences between both surgeries (SASJ and OAGB) were noted. Conclusion: Remission rates of DM are higher in SASJ in comparison to OAGB. SASJ had similar weight loss, BMI lo
导言:减肥手术是治疗病态肥胖及其相关并发症(包括 2 型糖尿病、高血压和血脂异常)的有效方法。单吻合套管空肠术(SASJ)尚未在文献中得到充分研究,也未与其他减肥手术进行比较。我们的目的是比较单吻合胃旁路术(OAGB)和 SASJ 在降低体重指数(BMI)、缓解并发症、术后并发症和营养状况方面的效果。患者和方法:一项随机临床试验,患者以 1:1 的比例接受 OAGB 或 SASJ 手术治疗病态肥胖。参与者自 2022 年 4 月起在艾因夏姆斯大学医院(一家三级医疗中心)的减肥手术部门登记,并接受至少 12 个月的随访。纳入标准为:年龄在18至60岁之间,体重指数大于或等于40,或体重指数为35至40并伴有肥胖相关合并症。术前上消化道内镜检查显示胃食管反流病 C 级或巴雷特食管、曾接受过上消化道手术或肝硬化、口服类固醇治疗、曾接受过减肥手术、有严重心血管疾病或严重限制性呼吸系统疾病等腹腔充气禁忌症、不适合全身麻醉、明显腹股沟疝、患有重大精神疾病和怀孕的患者将被排除在外。主要结果包括体重减轻、体重指数(BMI)下降、总重量下降率和超重率(EWL%)。次要结果包括合并症、胆汁反流、术后并发症、再次入院、再次手术和营养状况。结果:自 2022 年 4 月以来,共有 68 名患者加入了这项研究。整个队列的平均年龄、体重和 BMI 分别为(38.32±10.08)岁、(124.72±18.75)公斤和(43.97±5.47)公斤/米 2。与 OAGB 相比,SASJ 中患有 DM 和/或 HTN 的患者人数更多(DM 38.2%,HTN 47.1%)。两组患者在术后并发症(P=0.135)、再住院(P=1)、再次手术(P=0.555)和胆汁反流(P=0.09)方面无明显统计学差异。SASJ 组和 OAGB 组在术后 6 个月和 12 个月随访时的体重减轻率、体重指数(BMI)和 EWL 百分比相当,但 OAGB 组仅在 6 个月随访时的总体重减轻率显著高于 SASJ 组。与 OAGB 患者相比,SASJ 患者的 DM 缓解率明显更高(P=0.012)。两组患者在高血压(P=0.07)和血脂异常(P=0.03)的缓解率上没有明显差异。与 SASJ 患者相比,OAGB 患者术后胆结石的发生率更高(P=0.001)。所有患者都没有贫血、低白蛋白血症或缺铁。在维生素 D 和钙方面,两种手术(SASJ 和 OAGB)之间无明显差异。结论:与 OAGB 相比,SASJ 的 DM 缓解率更高。SASJ 与 OAGB 的体重减轻、BMI 下降和 EWL 相似。两种手术在术后并发症、再入院和再手术方面的结果相当,但胆结石的发生率在 OAGB 组明显较高。
{"title":"Single anastomosis sleeve jejunal bypass versus one anastomosis gastric bypass in treatment of obesity and metabolic diseases: A randomized controlled trial","authors":"Y. K. S. M. Salem, S. A. A. Maaty, K. S. Abdelsamee, Ahmed M. Farrag","doi":"10.21608/ejsur.2024.357109","DOIUrl":"https://doi.org/10.21608/ejsur.2024.357109","url":null,"abstract":"Introduction: Bariatric surgeries are an effective treatment for morbid obesity and its associated co-morbidities including type 2 diabetes mellitus, hypertension (HTN), and dyslipidemia. Single anastomosis sleeve jejunal (SASJ) has not been well studied in the literature or compared with other bariatric surgeries. We aim to compare one anastomosis gastric bypass (OAGB) to SASJ in terms of reduction in BMI, resolution of co-morbidities, postoperative complications, and nutritional status. Patients and Methods: A randomized clinical trial of patients undergoing either OAGB or SASJ at 1:1 ratio for treatment of morbid obesity. Participants were enrolled since April 2022 and were followed for at least 12 months at bariatric surgery department at Ain Shams University Hospital, a tertiary care center. Inclusion criteria for participant’s enrollment were age between 18 and 60 years old and BMI greater than or equal to 40 or BMI 35–40 with obesity-related comorbidities. Patients were excluded if preoperative upper gastrointestinal endoscopy showed GERD class C or Barrett’s esophagus, previous upper gastrointestinal tract surgery or liver cirrhosis, on oral steroid therapy, previous bariatric surgery, contraindications for abdominal insufflation as those with severe cardiovascular or severe restrictive respiratory diseases, Not fit for general anesthesia, significant abdominal ventral hernia, major psychiatric illness, and pregnant. Primary outcome involves weight loss, BMI loss, total weight loss %, and excess weight loss (EWL%). Secondary outcomes include resolution of comorbidities, biliary reflux, postoperative complications, readmissions, reoperations, and nutritional status. Results: Since April 2022, 68 patients have been enrolled into the study. The mean age, weight, and BMI of the entire cohort are 38.32±10.08 years old, 124.72±18.75 kg, and 43.97±5.47 kg/m 2 . A higher number of patients had DM and/or HTN in SASJ (38.2% DM, 47.1% HTN) compared with OAGB. Comparison between both groups showed no significant statistical difference in postoperative complications ( P=0.135 ), readmissions ( P=1 ), reoperations ( P=0.555 ), and bile reflux ( P=0.09 ). Both SASJ and OAGB groups had comparable postoperative weight loss, BMI, EWL % at 6 and 12 months of follow-up, however, OAGB had significantly higher total weight loss % at 6 months only. SASJ patients had a significantly higher rate of resolution from DM compared with OAGB patients ( P=0.012 ). No significant difference between both groups in the resolution of HTN ( P=0.07 ) and dyslipidemia ( P=0.03 ). Patients who had OAGB had a higher rate of gallstones postoperatively compared with SASJ patients ( P=0.001 ). None of the patients had anemia, hypoalbuminemia, or iron deficiency. Regarding vitamin D and calcium, no significant differences between both surgeries (SASJ and OAGB) were noted. Conclusion: Remission rates of DM are higher in SASJ in comparison to OAGB. SASJ had similar weight loss, BMI lo","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141691538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Latest follow-up after primary surgical correction of tetralogy of Fallot in adulthood 成年期法洛四联症初次手术矫正后的最新随访情况
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357123
Amr Alsalakawy, Hassan Moftah, WALEED I ibraheem, Ahmed M Afifi, Ahmed Mahgoub, Mohamed Adel
. ABSTRACT Background: Tetralogy of Fallot (TOF) is a prevalent congenital heart disease that requires early surgical intervention in infancy to enhance survival rates. However, some overlooked cases of TOF can persist into adulthood. Yet, they are vulnerable to serious complications from the long-standing cyanosis, which emphasizes the need for surgical correction. Nevertheless, primary surgical repair poses greater risks compared to pediatric cases due to coagulation defects, myocardial dysfunction, and previous palliative procedures. Additionally, severely dysplastic pulmonary valves often cannot be preserved, and a transannular patch can result in severe pulmonary regurgitation (PR), leading to complications such as right ventricle dysfunction and arrhythmia. Hence, in adult patients, pulmonary valve replacement (PVR) is a strong bailout option when valve preservation techniques fail to achieve satisfactory outcomes. Aim: The objective of this study is to examine information gathered from 56 adult patients with TOF who received primary repair with PVR. The study will investigate the patients’ preoperative characteristics, operative details, early postoperative progress, and recent follow-up results. The study findings will enhance the current understanding of PVR outcomes and the challenges adult TOF patients face. Patients and Methods: We studied 56 patients, 16 years of age or older, who underwent primary surgical correction of TOF in adulthood using PVR from March 2013 till March 2023. We examined their preoperative characteristics, operative technical details, postoperative outcomes, and findings from their last follow-up visit. Results: The mean age is 22.16±7.06 years. Twenty-one (37.5%) patients had palliative procedures. The majority were in NYHA grade 3. The mean oxygen saturation was 76.7%, while the mean hemoglobin level was 19.18. Cyanotic spells occurred in 10.71% of patients, and palpitations in 3.57%. The mean right ventricular outflow tract (RVOT) pressure gradient (PG) was 94.55 mmHg. Twenty-eight patients had a PVR with a freestyle valve, while the other half received tissue valves or homografts. The postoperative mean RVOT PG was 14.93 mmHg. There was no significant gradient difference between the different valve types. The mean ICU stay was 3.73 days, while the mean hospital stay was 8.64 days. Pleural effusion was the most common complication occurring in seven patients. While high intercostal tube drainage requiring evacuation occurred in four patients. Only one patient required revision of his ventricular septal defect patch due to significant residual. Cerebrovascular stroke occurred in two patients and resolved completely before discharge. The cohort was followed yearly. The mean follow-up years was 3.52 years. Fifty-four patients remained in NYHA 0. The mean RVOT PG was 21.3 mmHg, without significant difference between valves. Eleven patients had grade 1 PR and one had grade 2 PR. Conclusion: TOF repair in adulthood
.摘要 背景:法洛氏四联症(TOF)是一种常见的先天性心脏病,需要在婴儿期及早进行手术干预以提高存活率。然而,一些被忽视的 TOF 病例可能会持续到成年。然而,他们很容易因长期发绀而出现严重并发症,这就强调了手术矫治的必要性。然而,与儿科病例相比,由于凝血功能缺陷、心肌功能障碍以及之前的姑息性手术,初级手术修复的风险更大。此外,严重发育不良的肺动脉瓣通常无法保留,而经环形修补可能会导致严重的肺动脉瓣反流(PR),从而引发右心室功能障碍和心律失常等并发症。因此,在成人患者中,当瓣膜保留技术无法达到满意的效果时,肺动脉瓣置换术(PVR)是一个强有力的救助选择。目的:本研究的目的是检查从 56 名接受 PVR 初级修复术的 TOF 成年患者那里收集到的信息。研究将调查患者的术前特征、手术细节、术后早期进展以及近期随访结果。研究结果将加深目前对 PVR 结果和成年 TOF 患者所面临挑战的了解。患者和方法:我们研究了自 2013 年 3 月至 2023 年 3 月期间接受 PVR 初级手术矫正 TOF 的 56 名 16 岁或以上成年患者。我们研究了他们的术前特征、手术技术细节、术后结果以及最后一次随访的结果。结果:平均年龄为(22.16±7.06)岁。21名患者(37.5%)接受了姑息性手术。大多数患者属于 NYHA 3 级。平均血氧饱和度为 76.7%,平均血红蛋白水平为 19.18。10.71%的患者出现发绀,3.57%的患者出现心悸。右心室流出道(RVOT)平均压力梯度(PG)为 94.55 mmHg。28名患者使用自由瓣膜进行了PVR,另一半患者接受了组织瓣膜或同种瓣膜移植。术后 RVOT PG 平均值为 14.93 mmHg。不同瓣膜类型之间没有明显的梯度差异。重症监护室平均住院时间为 3.73 天,平均住院时间为 8.64 天。胸腔积液是最常见的并发症,有七名患者发生了胸腔积液。有四名患者因肋间管引流过多而需要排空。只有一名患者因有明显残留物而需要对室间隔缺损补片进行修补。两名患者发生了脑血管中风,并在出院前完全康复。该组患者每年接受一次随访。平均随访年限为 3.52 年。54名患者的NYHA仍为0级,平均RVOT PG为21.3 mmHg,不同瓣膜之间无明显差异。11 名患者出现 1 级 PR,1 名患者出现 2 级 PR。结论:在成年期使用 PVR 进行 TOF 修复是一种安全、有效且可重复的策略。必须进行更长时间的随访,以确定所用生物瓣膜的退化率。
{"title":"Latest follow-up after primary surgical correction of tetralogy of Fallot in adulthood","authors":"Amr Alsalakawy, Hassan Moftah, WALEED I ibraheem, Ahmed M Afifi, Ahmed Mahgoub, Mohamed Adel","doi":"10.21608/ejsur.2024.357123","DOIUrl":"https://doi.org/10.21608/ejsur.2024.357123","url":null,"abstract":". ABSTRACT Background: Tetralogy of Fallot (TOF) is a prevalent congenital heart disease that requires early surgical intervention in infancy to enhance survival rates. However, some overlooked cases of TOF can persist into adulthood. Yet, they are vulnerable to serious complications from the long-standing cyanosis, which emphasizes the need for surgical correction. Nevertheless, primary surgical repair poses greater risks compared to pediatric cases due to coagulation defects, myocardial dysfunction, and previous palliative procedures. Additionally, severely dysplastic pulmonary valves often cannot be preserved, and a transannular patch can result in severe pulmonary regurgitation (PR), leading to complications such as right ventricle dysfunction and arrhythmia. Hence, in adult patients, pulmonary valve replacement (PVR) is a strong bailout option when valve preservation techniques fail to achieve satisfactory outcomes. Aim: The objective of this study is to examine information gathered from 56 adult patients with TOF who received primary repair with PVR. The study will investigate the patients’ preoperative characteristics, operative details, early postoperative progress, and recent follow-up results. The study findings will enhance the current understanding of PVR outcomes and the challenges adult TOF patients face. Patients and Methods: We studied 56 patients, 16 years of age or older, who underwent primary surgical correction of TOF in adulthood using PVR from March 2013 till March 2023. We examined their preoperative characteristics, operative technical details, postoperative outcomes, and findings from their last follow-up visit. Results: The mean age is 22.16±7.06 years. Twenty-one (37.5%) patients had palliative procedures. The majority were in NYHA grade 3. The mean oxygen saturation was 76.7%, while the mean hemoglobin level was 19.18. Cyanotic spells occurred in 10.71% of patients, and palpitations in 3.57%. The mean right ventricular outflow tract (RVOT) pressure gradient (PG) was 94.55 mmHg. Twenty-eight patients had a PVR with a freestyle valve, while the other half received tissue valves or homografts. The postoperative mean RVOT PG was 14.93 mmHg. There was no significant gradient difference between the different valve types. The mean ICU stay was 3.73 days, while the mean hospital stay was 8.64 days. Pleural effusion was the most common complication occurring in seven patients. While high intercostal tube drainage requiring evacuation occurred in four patients. Only one patient required revision of his ventricular septal defect patch due to significant residual. Cerebrovascular stroke occurred in two patients and resolved completely before discharge. The cohort was followed yearly. The mean follow-up years was 3.52 years. Fifty-four patients remained in NYHA 0. The mean RVOT PG was 21.3 mmHg, without significant difference between valves. Eleven patients had grade 1 PR and one had grade 2 PR. Conclusion: TOF repair in adulthood ","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141713691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative EUS elastography: A new tool for predicting postoperative pancreatic fistulas 术前 EUS 弹性成像:预测术后胰瘘的新工具
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357132
Doaa A. Mansour, Sami M. Said, Younan K. Ayoub, Abanob Talaat, Ahmed M. Ghobashya
. ABSTRACT Background: Post-operative Pancreatic fistula (POPF) is one of the significant serious complications following a PancreaticoDudenectomy (PD) or Distal Pancreatectomy (DP), and its incidence ranges from 13 to 50%. Identification of patients at a greater risk could assist in tailoring the management approach, which may involve implementing different methods for anastomotic techniques, placing additional drainage, and using somatostatin analogues as a preventive measure. Objectives: Assessing the stiffness of the pancreas using EUS elastography before surgery is an objective, quantitative, and dependable method. This detailed evaluation prior to surgery could enable surgeons to personalize and adjust the management plan in the perioperative period, leading to the best possible outcomes. Patients and Methods: This prospective case series study was conducted in Cairo University (Kasr Al-Aini Hospital) over a 12-month period between April 2021 and March 2022. Fifty-one patients underwent pancreatic surgeries either PD or DP were enrolled into the study. EUS was done for all patients by the same operator using pentax 3870 attached to a HITACHI Avius sonographic machine. Elastography was performed for all patients in two different points of pancreas and the mean was taken for both. The reading was translated to soft, intermediate, hard texture of pancreas where soft was ≤1.40 m/s, intermediate was >1.40 m/s but ≤2 m/s, hard was >2 m/s. Amylase in drain was done at day 1, 3, 5 postoperative. Results: A statistically significant correlation was observed between presence of pancreatic fistula and EUS findings, as soft pancreas showed higher significant prevalence of pancreatic fistula ( P=0.030 ). On the other hand, grade A fistula was higher in cases with soft and intermediate stiffness but did not reach the significance level ( P=0.053 ). By using ROC-curve analysis, EUS elastography can insignificantly predict postoperative pancreatic fistula in patients undergoing pancreatic surgeries at cutoff 2.0 m/s with sensitivity, specificity, PPV and NPV was 95.2%, 30.0%, 57.6% and 86.2% respectively ( P=0.514 ). Conclusion: The current research showed that pancreatic stiffness could be measured by preoperative elastography. Moreover, we discovered that the elastic ratio can be employed to detect a ‘soft pancreas’. This information is valuable as it can help predict the probability of POPF following pancreatectomy.
.摘要 背景:术后胰瘘(POPF)是胰十二指肠切除术(PD)或胰远端切除术(DP)后的重要严重并发症之一,其发生率为 13% 至 50%。识别风险较高的患者有助于调整治疗方法,其中可能包括采用不同的吻合技术方法、放置额外的引流管以及使用体生长抑素类似物作为预防措施。目标:手术前使用 EUS 弹性成像评估胰腺硬度是一种客观、定量且可靠的方法。手术前的这种详细评估可使外科医生在围手术期个性化并调整管理计划,从而获得最佳治疗效果。患者和方法:这项前瞻性病例系列研究于 2021 年 4 月至 2022 年 3 月在开罗大学(Kasr Al-Aini 医院)进行,为期 12 个月。51名接受胰腺手术(PD或DP)的患者被纳入研究。所有患者的 EUS 均由同一操作员使用连接到 HITACHI Avius 超声波机的 pentax 3870 进行。对所有患者的胰腺两个不同点进行弹性成像,并取两者的平均值。读数被转换为胰腺的软、中、硬质地,其中软质地≤1.40 m/s,中质地>1.40 m/s但≤2 m/s,硬质地>2 m/s。术后第 1、3、5 天在引流管中检测淀粉酶。结果胰瘘的存在与 EUS 结果之间存在统计学意义上的显著相关性,软胰腺显示出更高的胰瘘患病率 ( P=0.030)。另一方面,A 级瘘在软性和中等硬度的病例中发生率较高,但未达到显著性水平(P=0.053)。通过 ROC 曲线分析,在临界值为 2.0 m/s 时,EUS 弹性成像对胰腺手术患者术后胰瘘的预测不显著,敏感性、特异性、PPV 和 NPV 分别为 95.2%、30.0%、57.6% 和 86.2% ( P=0.514)。结论目前的研究表明,术前弹性成像可以测量胰腺硬度。此外,我们还发现弹性比率可用于检测 "软胰腺"。这一信息很有价值,因为它有助于预测胰腺切除术后发生 POPF 的概率。
{"title":"Preoperative EUS elastography: A new tool for predicting postoperative pancreatic fistulas","authors":"Doaa A. Mansour, Sami M. Said, Younan K. Ayoub, Abanob Talaat, Ahmed M. Ghobashya","doi":"10.21608/ejsur.2024.357132","DOIUrl":"https://doi.org/10.21608/ejsur.2024.357132","url":null,"abstract":". ABSTRACT Background: Post-operative Pancreatic fistula (POPF) is one of the significant serious complications following a PancreaticoDudenectomy (PD) or Distal Pancreatectomy (DP), and its incidence ranges from 13 to 50%. Identification of patients at a greater risk could assist in tailoring the management approach, which may involve implementing different methods for anastomotic techniques, placing additional drainage, and using somatostatin analogues as a preventive measure. Objectives: Assessing the stiffness of the pancreas using EUS elastography before surgery is an objective, quantitative, and dependable method. This detailed evaluation prior to surgery could enable surgeons to personalize and adjust the management plan in the perioperative period, leading to the best possible outcomes. Patients and Methods: This prospective case series study was conducted in Cairo University (Kasr Al-Aini Hospital) over a 12-month period between April 2021 and March 2022. Fifty-one patients underwent pancreatic surgeries either PD or DP were enrolled into the study. EUS was done for all patients by the same operator using pentax 3870 attached to a HITACHI Avius sonographic machine. Elastography was performed for all patients in two different points of pancreas and the mean was taken for both. The reading was translated to soft, intermediate, hard texture of pancreas where soft was ≤1.40 m/s, intermediate was >1.40 m/s but ≤2 m/s, hard was >2 m/s. Amylase in drain was done at day 1, 3, 5 postoperative. Results: A statistically significant correlation was observed between presence of pancreatic fistula and EUS findings, as soft pancreas showed higher significant prevalence of pancreatic fistula ( P=0.030 ). On the other hand, grade A fistula was higher in cases with soft and intermediate stiffness but did not reach the significance level ( P=0.053 ). By using ROC-curve analysis, EUS elastography can insignificantly predict postoperative pancreatic fistula in patients undergoing pancreatic surgeries at cutoff 2.0 m/s with sensitivity, specificity, PPV and NPV was 95.2%, 30.0%, 57.6% and 86.2% respectively ( P=0.514 ). Conclusion: The current research showed that pancreatic stiffness could be measured by preoperative elastography. Moreover, we discovered that the elastic ratio can be employed to detect a ‘soft pancreas’. This information is valuable as it can help predict the probability of POPF following pancreatectomy.","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141696139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of central versus distal pancreatectomy in management of pancreatic body tumours: A combined retrospective and prospective study 评估胰腺体肿瘤治疗中的中央与远端胰腺切除术:回顾性和前瞻性联合研究
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357139
Ali Salem, Amgad Fouad, Tarek Salah, Mohamed Elyamany, M. El Dosoky
. ABSTRACT Background: Central pancreatectomy is a promising surgical option for patients with benign and low-grade neoplasms affecting the pancreatic body/neck region, as it preserves more pancreatic parenchyma than distal pancreatectomy. However, dealing with two pancreatic stumps carries an increased potential for pancreatic fistula. That is why we conducted this investigation to compare the previous two techniques (central vs. distal pancreatectomy) in patients with such neoplasms. Patients and Methods: Seventy patients were enrolled in our combined prospective and retrospective trial. Group A included 35 central pancreatectomy patients, while Group B included 35 distal pancreatectomy patients. Results: Central pancreatectomy was associated with a prolonged operative time compared to the distal procedure. Tumor size and pathology did not differ between the two groups. However, the length of the resected pancreatic tissue was shorter in Group A. Patients in the same group had longer ICU stays, hospitalization periods, and longer duration till oral intake. However, the incidence of pancreatic fistula was comparable between the two groups (22.9% vs. 25.7% in the two groups, respectively). Other complications, including hemorrhage and wound infection, did not differ between the two groups. Mortality occurred in only one patient in Group A due to secondary hemorrhage. Both endocrine and exocrine insufficiencies were more encountered after distal pancreatectomy compared to the central one. Conclusion: Central pancreatectomy is associated with significantly better postoperative pancreatic endocrine and exocrine functions without increased complication rates compared to distal pancreatectomy.
.摘要 背景:对于胰腺体/颈部良性肿瘤和低级别肿瘤患者来说,中央胰腺切除术是一种很有前景的手术选择,因为它比远端胰腺切除术保留了更多的胰腺实质。然而,处理两个胰腺残端增加了胰瘘的可能性。因此,我们进行了这项调查,以比较前两种技术(中央与远端胰腺切除术)在此类肿瘤患者中的应用情况。患者和方法:我们的前瞻性和回顾性联合试验共招募了 70 名患者。A 组包括 35 名中央胰腺切除术患者,B 组包括 35 名远端胰腺切除术患者。结果与远端胰腺切除术相比,中央胰腺切除术的手术时间更长。两组患者的肿瘤大小和病理结果没有差异。然而,A 组患者切除的胰腺组织长度较短。同组患者在重症监护室的停留时间和住院时间较长,口服药物的时间也较长。不过,两组胰瘘的发生率相当(两组分别为 22.9% 对 25.7%)。其他并发症,包括出血和伤口感染,在两组之间没有差异。只有 A 组的一名患者因继发性出血而死亡。与胰腺中央切除术相比,胰腺远端切除术后更容易出现内分泌和外分泌功能不全。结论与胰腺远端切除术相比,胰腺中央切除术的术后胰腺内分泌和外分泌功能明显更好,且并发症发生率不增加。
{"title":"Evaluation of central versus distal pancreatectomy in management of pancreatic body tumours: A combined retrospective and prospective study","authors":"Ali Salem, Amgad Fouad, Tarek Salah, Mohamed Elyamany, M. El Dosoky","doi":"10.21608/ejsur.2024.357139","DOIUrl":"https://doi.org/10.21608/ejsur.2024.357139","url":null,"abstract":". ABSTRACT Background: Central pancreatectomy is a promising surgical option for patients with benign and low-grade neoplasms affecting the pancreatic body/neck region, as it preserves more pancreatic parenchyma than distal pancreatectomy. However, dealing with two pancreatic stumps carries an increased potential for pancreatic fistula. That is why we conducted this investigation to compare the previous two techniques (central vs. distal pancreatectomy) in patients with such neoplasms. Patients and Methods: Seventy patients were enrolled in our combined prospective and retrospective trial. Group A included 35 central pancreatectomy patients, while Group B included 35 distal pancreatectomy patients. Results: Central pancreatectomy was associated with a prolonged operative time compared to the distal procedure. Tumor size and pathology did not differ between the two groups. However, the length of the resected pancreatic tissue was shorter in Group A. Patients in the same group had longer ICU stays, hospitalization periods, and longer duration till oral intake. However, the incidence of pancreatic fistula was comparable between the two groups (22.9% vs. 25.7% in the two groups, respectively). Other complications, including hemorrhage and wound infection, did not differ between the two groups. Mortality occurred in only one patient in Group A due to secondary hemorrhage. Both endocrine and exocrine insufficiencies were more encountered after distal pancreatectomy compared to the central one. Conclusion: Central pancreatectomy is associated with significantly better postoperative pancreatic endocrine and exocrine functions without increased complication rates compared to distal pancreatectomy.","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of graft diameter on the patency rates of axillaryaxillary arteriovenous grafts in hemodialysis patients 移植物直径对血液透析患者腋窝动静脉移植物通畅率的影响
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357105
Amr M. Elshafei, Hossam A Elwakeel, Dina G. Abdelzaher, Mohamed Emad Eldin, Farag K Mohamed
Introduction : End-stage renal disease (ESRD) arises from several heterogeneous disease pathways that permanent alter renal function and structure over months or years. Hemodialysis (HD) is a lifeline treatment for cases with ESRD. A ratio of HD cases exhaust all methods for permanent vascular access (fistula or graft) in both upper limbs. Aim: The current study aims to compare 8 and 6 mm extended polytetrafluoroethylene (PTFE) grafts according to the primary patency in cases undergoing axi-ax arteriovenous grafts. Patients and methods: This retrospective, prospective case–control cohort study included all patients with ESRD referred to the Vascular Outpatient Clinic, Mansoura University hospitals, seeking for creation of HD access and decided for arteriovenous synthetic graft due to the lack of suitable autogenous veins in the arms patient were classified into two groups, in the first group (A) an 8 mm PTFE graft (26 patients) in the second group (B) a 6 mm PTFE graft, grafts (21 patients) were placed on the chest wall anastomosed between first part axillary artery and axillary vein. Results : This study was conducted on 47 patients, a 6 mm graft was used on 21 patients and an 8 mm graft on 26 patients. There was a statistically significant difference between the graft 6 mm group and the graft 8 mm group regarding preoperative axillary artery diameter and preoperative vein diameter ( P < 0.001 and 0.001, respectively) and significant difference between graft 6 mm group and graft 8 mm group regarding complications (thrombosis) ( P = 0.033). And nonsignificant regarding infection ( P = 1.0). Conclusion : The current study revealed that without considering certain changes in 6 and 8 mm grafts, primary patency can be improved by placing 8 mm grafts while respecting the axillary artery and vein diameters.
导言:终末期肾病(ESRD)由多种异质性疾病途径引起,在数月或数年内永久性地改变肾功能和结构。血液透析(HD)是终末期肾病患者的生命线。有一定比例的血液透析患者用尽了所有方法(造瘘或移植)以获得双上肢的永久性血管通路。目的:本研究旨在比较 8 毫米和 6 毫米加长型聚四氟乙烯(PTFE)移植物在接受轴-轴动静脉移植物治疗病例中的主要通畅性。患者和方法:这项回顾性、前瞻性病例对照队列研究纳入了所有转诊至曼苏拉大学医院血管门诊的 ESRD 患者,这些患者寻求建立 HD 通路,但由于手臂上缺乏合适的自体静脉而决定采用动静脉合成移植物,患者被分为两组、第一组(A)采用 8 毫米聚四氟乙烯移植物(26 名患者);第二组(B)采用 6 毫米聚四氟乙烯移植物,移植物(21 名患者)被放置在胸壁上,与第一部分腋动脉和腋静脉吻合。结果:这项研究针对 47 名患者,21 名患者使用了 6 毫米移植物,26 名患者使用了 8 毫米移植物。在术前腋动脉直径和术前静脉直径方面,6 毫米移植物组和 8 毫米移植物组之间存在显著差异(P < 0.001 和 0.001);在并发症(血栓形成)方面,6 毫米移植物组和 8 毫米移植物组之间存在显著差异(P = 0.033)。在感染方面无显著差异(P = 1.0)。结论:目前的研究表明,在不考虑 6 毫米和 8 毫米移植物的某些变化的情况下,在尊重腋动脉和静脉直径的前提下,放置 8 毫米移植物可以提高初次通畅率。
{"title":"The influence of graft diameter on the patency rates of axillaryaxillary arteriovenous grafts in hemodialysis patients","authors":"Amr M. Elshafei, Hossam A Elwakeel, Dina G. Abdelzaher, Mohamed Emad Eldin, Farag K Mohamed","doi":"10.21608/ejsur.2024.357105","DOIUrl":"https://doi.org/10.21608/ejsur.2024.357105","url":null,"abstract":"Introduction : End-stage renal disease (ESRD) arises from several heterogeneous disease pathways that permanent alter renal function and structure over months or years. Hemodialysis (HD) is a lifeline treatment for cases with ESRD. A ratio of HD cases exhaust all methods for permanent vascular access (fistula or graft) in both upper limbs. Aim: The current study aims to compare 8 and 6 mm extended polytetrafluoroethylene (PTFE) grafts according to the primary patency in cases undergoing axi-ax arteriovenous grafts. Patients and methods: This retrospective, prospective case–control cohort study included all patients with ESRD referred to the Vascular Outpatient Clinic, Mansoura University hospitals, seeking for creation of HD access and decided for arteriovenous synthetic graft due to the lack of suitable autogenous veins in the arms patient were classified into two groups, in the first group (A) an 8 mm PTFE graft (26 patients) in the second group (B) a 6 mm PTFE graft, grafts (21 patients) were placed on the chest wall anastomosed between first part axillary artery and axillary vein. Results : This study was conducted on 47 patients, a 6 mm graft was used on 21 patients and an 8 mm graft on 26 patients. There was a statistically significant difference between the graft 6 mm group and the graft 8 mm group regarding preoperative axillary artery diameter and preoperative vein diameter ( P < 0.001 and 0.001, respectively) and significant difference between graft 6 mm group and graft 8 mm group regarding complications (thrombosis) ( P = 0.033). And nonsignificant regarding infection ( P = 1.0). Conclusion : The current study revealed that without considering certain changes in 6 and 8 mm grafts, primary patency can be improved by placing 8 mm grafts while respecting the axillary artery and vein diameters.","PeriodicalId":22550,"journal":{"name":"The Egyptian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141715419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The Egyptian Journal of Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1