Garazi Retegui, Jaione Etxeberria, María Dolores Ugarte
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引用次数: 0
Abstract
Rare cancers affect millions of people worldwide each year. However, estimating incidence or mortality rates associated with rare cancers presents important difficulties and poses new statistical methodological challenges. In this paper, we expand the collection of multivariate spatio-temporal models by introducing adaptable shared spatio-temporal components to enable a comprehensive analysis of both incidence and cancer mortality in rare cancer cases. These models allow the modulation of spatio-temporal effects between incidence and mortality, allowing for changes in their relationship over time. The new models have been implemented in INLA using r-generic constructions. We conduct a simulation study to evaluate the performance of the new spatio-temporal models. Our results show that multivariate spatio-temporal models incorporating a flexible shared spatio-temporal term outperform conventional multivariate spatio-temporal models that include specific spatio-temporal effects for each health outcome. We use these models to analyze incidence and mortality data for pancreatic cancer and leukaemia among males across 142 administrative health care districts of Great Britain over a span of nine biennial periods (2002–2019).
期刊介绍:
Environmental and Ecological Statistics publishes papers on practical applications of statistics and related quantitative methods to environmental science addressing contemporary issues.
Emphasis is on applied mathematical statistics, statistical methodology, and data interpretation and improvement for future use, with a view to advance statistics for environment, ecology and environmental health, and to advance environmental theory and practice using valid statistics.
Besides clarity of exposition, a single most important criterion for publication is the appropriateness of the statistical method to the particular environmental problem. The Journal covers all aspects of the collection, analysis, presentation and interpretation of environmental data for research, policy and regulation. The Journal is cross-disciplinary within the context of contemporary environmental issues and the associated statistical tools, concepts and methods. The Journal broadly covers theory and methods, case studies and applications, environmental change and statistical ecology, environmental health statistics and stochastics, and related areas. Special features include invited discussion papers; research communications; technical notes and consultation corner; mini-reviews; letters to the Editor; news, views and announcements; hardware and software reviews; data management etc.