Seroprevalence of infectious markers HCV, HBV, HIV and the agent of syphilis among blood donors from the blood transfusion center (BTC of Constantine) in a hospital in eastern Algeria

Abstract

Microbial agents transmitted by blood transfusion, HBV, HCV, HIV and syphilis remain a major problem for transfusion safety. The objective of this study is to determine the seroprevalence of infectious markers in order to contribute to the improvement of the safe and sufficient supply of blood. This is a retrospective cross-sectional study carried out at the BTC SMK laboratory in Constantine covering the period from January 2019 to December 2021. Our sample is mainly composed of voluntary, adult, young and male donors. 9155 donors who underwent a screening examination during the period (2019-2021). The seroprevalence of HBV, HCV, HIV and syphilis was respectively 0.40%, 0.12%, 0%, 0.14%, with a male predominance whose age group [36-45 [ presents the highest frequency of HCV, HBV and syphilis. Our results justify donor selection and screening tests.