Implant-Prosthetic Rehabilitation of the Agenesis of Maxillary Lateral Incisors: A 2-Year Prospective Clinical Study with Full Digital Workflow

R. Sorrentino, M. I. Di Mauro, G. Ruggiero, R. Leone, E. Ferrari Cagidiaco, Marco Annunziata, Marco Ferrari, F. Zarone
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Abstract

The main objectives of the present prospective clinical study were to evaluate the survival and success rates of implant-supported zirconia single crowns fabricated with a full digital workflow for the rehabilitation of mono- and bilateral agenesis of maxillary lateral incisors after 2 years of clinical function; biological and technical parameters affecting the prosthetic restorations were recorded, as well as the patient-satisfaction score. Twenty-two patients showing mono- or bilateral agenesis of the maxillary lateral incisors were included in this study, and a total of 30 narrow-diameter implants were inserted. Thirty screw-retained monolithic cubic zirconia single crowns with internal connections were fabricated. Objective outcome evaluations were performed by means of the Functional Implant Prosthodontic Score, whereas the patient-satisfaction score was evaluated using Visual Analog Scales. Descriptive statistics were performed and the Kaplan–Meier analysis was run to analyze time-to-event data. After 2 years of clinical function, the overall FIPS found in the present study was 9.2, whereas the average patient-satisfaction score was 8.7. The Kaplan–Meier analysis at the 2-year follow-up reported a cumulative survival rate of 100% and a cumulative success rate of 93.3%. The implant-prosthetic rehabilitation with a full digital workflow proved to be an effective and reliable procedure for the functional and aesthetic treatment of the agenesis of maxillary lateral incisors in the short-term. Clinical investigations with wider sample populations and longer observational follow-ups could be useful to validate, in the long-term, the clinical outcomes of the present prospective clinical study.
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上颌侧切牙缺失的种植修复治疗:采用全数字化工作流程的两年期前瞻性临床研究
本前瞻性临床研究的主要目的是评估采用全数字化工作流程制作的种植体支撑氧化锆单冠修复单侧和双侧上颌侧切牙缺失两年后的存活率和成功率;记录影响修复体的生物和技术参数以及患者满意度评分。本研究共纳入了22名上颌侧切牙单侧或双侧缺失的患者,共植入了30颗窄直径种植体。制作了 30 个带内连接的螺钉固位整体立方氧化锆单冠。客观结果评估采用种植修复功能评分法,患者满意度评分采用视觉模拟评分法。研究人员进行了描述性统计,并采用 Kaplan-Meier 分析法对事件发生时间的数据进行了分析。经过两年的临床功能锻炼后,本研究中发现的总体 FIPS 为 9.2,而患者满意度平均分为 8.7。两年随访的 Kaplan-Meier 分析显示,累计存活率为 100%,累计成功率为 93.3%。事实证明,在短期内,采用全数字化工作流程进行种植修复是一种有效、可靠的上颌侧切牙缺失的功能性和美学治疗方法。更广泛的样本人群和更长时间的随访观察将有助于长期验证本前瞻性临床研究的临床结果。
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