A multioutput classifier model for breast cancer treatment prediction

Intelligence-based medicine Pub Date : 2024-01-01 Epub Date: 2024-07-18 DOI:10.1016/j.ibmed.2024.100158
Emad Abd Al Rahman , Nur Intan Raihana Ruhaiyem , Majed Bouchahma
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Abstract

A growing number of new cases and fatalities occur each year due to breast cancer, making it the most frequent malignancy globally. Utilizing a multioutput classifier technique with algorithms such as CatBoost, XGBoost, NN, and NN Binary, this work presents a new model for predicting breast cancer treatments: surgery, radiotherapy, and chemotherapy. We tackle the pressing need for accurate medical treatments by developing a model to enhance the predicted accuracy of breast cancer treatment outcomes. The model accomplishes impressive results in predicting surgical outcomes; in particular, Neural Networks (NN and NN Binary) perform exceptionally well in terms of recall and precision, reaching 97 % accuracy and 98 % F1-scores. While the model's accuracy is only about 63 % for radiotherapy, it shows a promising recall of up to 84 %. Accuracy and precision in chemotherapy predictions remain stable at 82 %, with AUC-ROC values of up to 89 %, suggesting excellent discrimination ability. By combining multioutput classifiers with sophisticated algorithms, we hope to make treatment prediction models more tailored to individual breast cancer patient profiles, which might usher in a new era of tailored treatment plans and meet the rising demand for precision medicine in cancer care.

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用于乳腺癌治疗预测的多输出分类器模型
乳腺癌是全球最常见的恶性肿瘤,每年新增病例和死亡人数不断增加。本研究利用 CatBoost、XGBoost、NN 和 NN Binary 等算法的多输出分类器技术,提出了一种预测乳腺癌治疗(手术、放疗和化疗)的新模型。我们通过开发一种模型来提高乳腺癌治疗结果预测的准确性,从而满足人们对准确医疗的迫切需求。该模型在预测手术结果方面取得了令人印象深刻的成果;特别是,神经网络(NN 和 NN 二进制)在召回率和精确度方面表现出色,达到了 97% 的准确率和 98% 的 F1 分数。虽然该模型在放疗方面的准确率仅为 63%,但召回率却高达 84%,表现令人鼓舞。化疗预测的准确率和精确度稳定在 82%,AUC-ROC 值高达 89%,显示出卓越的分辨能力。我们希望通过将多输出分类器与复杂的算法相结合,使治疗预测模型更符合乳腺癌患者的个体情况,从而开创量身定制治疗方案的新时代,满足癌症护理领域对精准医疗不断增长的需求。
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来源期刊
Intelligence-based medicine
Intelligence-based medicine Health Informatics
CiteScore
5.00
自引率
0.00%
发文量
0
审稿时长
187 days
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