Development and validation of 3D printed anthropomorphic head phantom with eccentric holes for medical LINAC quality assurance testing in stereotactic radiosurgery

IF 1.7 4区 医学 Q3 ENGINEERING, BIOMEDICAL Medical Engineering & Physics Pub Date : 2024-08-01 DOI:10.1016/j.medengphy.2024.104217
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Abstract

Stereotactic Radiosurgery (SRS) for brain tumors using Medical Linear Accelerator (LINAC) demands high precision and accuracy. A specific Quality Assurance (QA) is essential for every patient undergoing SRS to protect nearby non-cancerous cells by ensuring that the X-ray beams are targeted according to tumor position. In this work, a water-filled generic anthropomorphic head phantom consisting of two removable parts with eccentric holes was developed using Additive Manufacturing (AM) process for performing QA in SRS. In the patient specific QA, the planned radiation dose using Treatment Planning System (TPS) was compared with the dose measured in the phantom. Also, the energy consistency of radiation beams was tested at 200 MU for different energy beams at the central and eccentric holes of the phantom using an ionization chamber. Experimentally examined results show that planned doses in TPS are reaching the target within a 5% deviation. The ratio of the dose delivered in the eccentric hole to the dose delivered to the central hole shows variations of less than 2% for the energy consistency test. The designed, low-cost water-filled anthropomorphic phantom is observed to improve positioning verification and accurate dosimetry of patient-specific QA in SRS treatment.

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开发和验证带偏心孔的 3D 打印拟人头部模型,用于立体定向放射手术中的医用 LINAC 质量保证测试
使用医用直线加速器(LINAC)进行脑肿瘤立体定向放射外科手术(SRS)要求高精度和高准确性。为保护附近的非癌细胞,确保 X 射线束根据肿瘤位置定向,对每位接受 SRS 的患者都必须进行特定的质量保证(QA)。在这项工作中,利用增材制造(AM)工艺开发了一个充水的通用拟人头部模型,该模型由两个带有偏心孔的可移动部件组成,用于在 SRS 中执行质量保证。在针对患者的质量保证中,使用治疗计划系统(TPS)计划的辐射剂量与在模型中测量的剂量进行了比较。此外,还使用电离室测试了 200 MU 不同能量光束在模型中心孔和偏心孔的辐射能量一致性。实验结果表明,TPS 的计划剂量在 5%的偏差范围内都能达到目标。在能量一致性测试中,偏心孔所受剂量与中心孔所受剂量之比变化小于 2%。据观察,所设计的低成本充水拟人模型可改善 SRS 治疗中患者特定 QA 的定位验证和精确剂量测定。
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来源期刊
Medical Engineering & Physics
Medical Engineering & Physics 工程技术-工程:生物医学
CiteScore
4.30
自引率
4.50%
发文量
172
审稿时长
3.0 months
期刊介绍: Medical Engineering & Physics provides a forum for the publication of the latest developments in biomedical engineering, and reflects the essential multidisciplinary nature of the subject. The journal publishes in-depth critical reviews, scientific papers and technical notes. Our focus encompasses the application of the basic principles of physics and engineering to the development of medical devices and technology, with the ultimate aim of producing improvements in the quality of health care.Topics covered include biomechanics, biomaterials, mechanobiology, rehabilitation engineering, biomedical signal processing and medical device development. Medical Engineering & Physics aims to keep both engineers and clinicians abreast of the latest applications of technology to health care.
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