Evidence of Structural Proteins of Toxoplasma gondii in Sera of Experimentally Infected Mice

Andreas Hassl , Horst Aspöck , Heinz Flamm
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引用次数: 4

Abstract

The present study was performed to clarify whether structural proteins are constituants of the antigens of Toxoplasma gondii which circulate in the sera of experimentally infected mice. Rabbits were immunized with mice sera containing circulating antigen, the rabbit sera were then tested for antibodies against Toxoplasma gondii. Low titers of specific antibodies, directed against cell wall proteins, could be detected. Thus, the circulating antigen must at least partially consist of structural proteins.

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实验感染小鼠血清中刚地弓形虫结构蛋白的证据
本研究旨在阐明结构蛋白是否为刚地弓形虫抗原的组成部分,该抗原在实验感染小鼠的血清中循环。用含循环抗原的小鼠血清免疫家兔,检测兔血清中弓形虫抗体。可以检测到针对细胞壁蛋白的低滴度特异性抗体。因此,循环抗原必须至少部分由结构蛋白组成。
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