Reattachment rate with pneumatic retinopexy versus pars plana vitrectomy for single break rhegmatogenous retinal detachment.

IF 3.7 2区 医学 Q1 OPHTHALMOLOGY British Journal of Ophthalmology Pub Date : 2024-08-19 DOI:10.1136/bjo-2023-324005
Aurora Pecaku, Isabela Martins Melo, Reut Shor, Carolina L M Francisconi, Samara Barbara Marafon, Varun Chaudhary, Roxane Jo Hillier, Rajeev H Muni
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Abstract

Aim: To assess the primary reattachment rate (PARR) in pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) meeting the Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomised Trial (PIVOT) criteria with a single break in detached retina.

Methods: A post hoc analysis of two clinical trials. To be included, patients with primary RRD had to meet PIVOT criteria but could have only one break in the detached retina. Patients with additional pathology in the attached retina were included in a secondary analysis. The primary outcome was PARR following PnR versus PPV at 1-year postoperatively.

Results: 162 patients were included. 53% (86/162) underwent PnR and 47% (76/162) had a PPV. 99% (85/86) and 86.8% (66/76) completed the 1-year follow-up visits in the PnR and PPV groups, respectively. PARR was 88.2% (75/85) in the PnR group and 90.9% (60/66) in the PPV group (p=0.6) with a mean postoperative logMAR best-corrected visual acuity of 0.19±0.25 versus 0.34±0.37 (Snellen 20/30 vs 20/44) (p=0.01) each in the PnR and PPV groups, respectively.In an additional analysis of patients who were also allowed to have any pathology in the attached retina, the PARR was 85% (91/107) and 91.6% (66/72) in the PnR and PPV groups, respectively (p=0.18).

Conclusions: PnR and PPV provide similar long-term PARR in a substantial proportion of patients meeting PIVOT criteria with only a single break in the detached retina. Therefore, in patients meeting these specific criteria, PnR is an appropriate first-line therapy as it offers superior functional outcomes without compromising PARR.

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气压式视网膜剥离术与玻璃体旁切除术治疗单个破损流变性视网膜脱离的再粘连率。
目的:评估符合 "气动视网膜剥离术与玻璃体切除术治疗原发性风湿性视网膜脱落结果随机试验"(PIVOT)标准的风湿性视网膜脱落(RRD)患者中,脱落视网膜单一断裂的原发性再附着率(PARR):方法:对两项临床试验进行事后分析。原发性RRD患者必须符合PIVOT标准,但脱落视网膜只能有一处破损,方可纳入试验。附着视网膜有其他病变的患者被纳入二次分析。主要结果是术后1年PnR与PPV的PARR:结果:共纳入 162 例患者。53%(86/162)的患者接受了 PnR,47%(76/162)的患者接受了 PPV。PnR组和PPV组分别有99%(85/86)和86.8%(66/76)的患者完成了为期1年的随访。PnR 组的 PARR 为 88.2%(75/85),PPV 组的 PARR 为 90.9%(60/66)(P=0.6),PnR 组和 PPV 组的术后平均 logMAR 最佳矫正视力分别为 0.19±0.25 对 0.34±0.37(斯奈伦 20/30 对 20/44)(P=0.01)。在对附着视网膜有任何病变的患者进行的额外分析中,PnR 组和 PPV 组的 PARR 分别为 85%(91/107)和 91.6%(66/72)(P=0.18):PnR和PPV可为相当一部分符合PIVOT标准且脱落视网膜仅有一处断裂的患者提供相似的长期PARR。因此,对于符合这些特定标准的患者,PnR 是一种合适的一线治疗方法,因为它能在不影响 PARR 的情况下提供更好的功能性结果。
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来源期刊
CiteScore
10.30
自引率
2.40%
发文量
213
审稿时长
3-6 weeks
期刊介绍: The British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists. BJO publishes clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology. It also provides major reviews and also publishes manuscripts covering regional issues in a global context.
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