Zeolitic Imidazolate Frameworks Based Anticancer Drug Delivery System Associated with Dual Action of Surface Charge and Lewis Base Ligand (Adv. Therap. 9/2024)
{"title":"Zeolitic Imidazolate Frameworks Based Anticancer Drug Delivery System Associated with Dual Action of Surface Charge and Lewis Base Ligand (Adv. Therap. 9/2024)","authors":"Wenjuan Yang, Lingling Tian, Ning Zhao, Lingyan Feng, Bingpu Zhou, Yongheng Zhu, Xinghua Gao, Yuan Zhang","doi":"10.1002/adtp.202470017","DOIUrl":null,"url":null,"abstract":"<p>Zeolitic imidazolate frameworks (ZIFs) are emerging as a promising nanocarrier platform for drug delivery. In article 2300447, Yongheng Zhu, Xinghua Gao, Yuan Zhang, and co-workers elucidate the crucial role of surface charge and Lewis-base ligand in determining cytotoxicity, cellular uptake, and intracellular release. These findings offer valuable insights for the screening of ZIF-based nanocarriers.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7284,"journal":{"name":"Advanced Therapeutics","volume":null,"pages":null},"PeriodicalIF":3.7000,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adtp.202470017","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Therapeutics","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adtp.202470017","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
Zeolitic imidazolate frameworks (ZIFs) are emerging as a promising nanocarrier platform for drug delivery. In article 2300447, Yongheng Zhu, Xinghua Gao, Yuan Zhang, and co-workers elucidate the crucial role of surface charge and Lewis-base ligand in determining cytotoxicity, cellular uptake, and intracellular release. These findings offer valuable insights for the screening of ZIF-based nanocarriers.
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