A Replication of a Nonsequential Renewal Model and a Failure to Attenuate Nonsequential Renewal with Extinction Cues

Brianna G. Sarno, Kathryn M. Kestner
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Abstract

Laboratory models of renewal are critical for understanding this form of behavioral relapse and informing clinical practice to reduce the occurrence of relapse and facilitate the maintenance of treatment gains. Nonsequential renewal is a modified procedure developed by (Sullivan et al. Journal of the Experimental Analysis of Behavior, 110(1), 74–86 2018) that provides an arrangement to study operant renewal in a manner more consistent with clients receiving clinical services, which involves exposing subjects to treatment and baseline conditions across two or more contexts. Experiment 1 replicated the procedure of (Craig et al. Journal of the Experimental Analysis of Behavior, 112(2), 210–223 2019) to compare ABA renewal of target responding in rats exposed to the nonsequential or sequential renewal procedure. Experiment 2 investigated the use of an olfactory extinction cue in mitigating renewal. In Experiment 1, the Nonsequential Group displayed a greater magnitude of renewal compared to the Sequential Group, consistent with the findings from (Craig et al. Journal of the Experimental Analysis of Behavior, 110(1), 74–86 2019) but inconsistent with those from (Sullivan et al. Journal of the Experimental Analysis of Behavior, 110(1), 74–86 2018) with human participants. The extinction cue did not mitigate renewal in Experiment 2. The use of a laboratory model of renewal that is more analogous to clinical settings may be valuable in a translational approach to investigating relapse-prevention techniques.

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非连续性更新模型的再现以及灭绝线索无法削弱非连续性更新的情况
更新的实验室模型对于理解这种行为复发形式和指导临床实践以减少复发的发生并促进治疗成果的维持至关重要。非序列更新是(Sullivan 等人,《行为实验分析杂志》,110(1),74-86 2018 年)开发的一种改进程序,它提供了一种以更符合接受临床服务的客户的方式来研究操作性更新的安排,其中涉及在两个或更多情境中让受试者接触治疗和基线条件。实验 1 复制了(Craig 等人,Journal of the Experimental Analysis of Behavior, 112(2), 210-223 2019)的程序,比较了 ABA 对暴露于非顺序或顺序更新程序的大鼠目标反应的更新。实验 2 调查了嗅觉消退线索在减轻目标反应更新中的作用。在实验 1 中,与顺序组相比,非顺序组的更新幅度更大,这与(Craig 等人,《行为实验分析杂志》,110(1),74-86 2019 年)的研究结果一致,但与(Sullivan 等人,《行为实验分析杂志》,110(1),74-86 2018 年)对人类参与者的研究结果不一致。在实验 2 中,灭绝线索并没有减轻更新。在研究复发预防技术的转化方法中,使用更类似于临床环境的实验室复发模型可能很有价值。
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