{"title":"Impacts of food additives on gut microbiota and host health","authors":"","doi":"10.1016/j.foodres.2024.114998","DOIUrl":null,"url":null,"abstract":"<div><p>The rapidly expanding food industry necessitates the use of food additives to achieve specific purposes. However, this raises new concerns in food safety due to the reported negative impacts of food additives on gut microbiota and host health, particularly in the context of continuous worldwide urbanization. This review summarizes the existing studies on the effects of different types of commonly used food additives on gut microbiota alteration, intestinal barrier disruption, metabolism disorder, and neurobehavior changes. These food additives, including emulsifiers, low-calorie sweeteners, inorganic nanoparticles, and preservatives, have been found to exert multifaceted impacts, primarily adverse effects, highlighting the potential risks associated with food additive exposure in various chronic diseases. Further research is warranted to elucidate the specific mechanisms, determine the relevance of these findings to humans, and clarify the suitability of certain food additives for vulnerable populations. It is crucial to note that natural food additives are not inherently superior to synthetic ones in terms of safety. Rigorous evaluation is still warranted before their widespread application in the food industry. Additionally, the potential synergistic effects of commonly used food additives combination in specific food categories on gut microbiota and host metabolism should be investigated to understand their relevance in real-world scenarios.</p></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":null,"pages":null},"PeriodicalIF":7.0000,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Research International","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0963996924010688","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The rapidly expanding food industry necessitates the use of food additives to achieve specific purposes. However, this raises new concerns in food safety due to the reported negative impacts of food additives on gut microbiota and host health, particularly in the context of continuous worldwide urbanization. This review summarizes the existing studies on the effects of different types of commonly used food additives on gut microbiota alteration, intestinal barrier disruption, metabolism disorder, and neurobehavior changes. These food additives, including emulsifiers, low-calorie sweeteners, inorganic nanoparticles, and preservatives, have been found to exert multifaceted impacts, primarily adverse effects, highlighting the potential risks associated with food additive exposure in various chronic diseases. Further research is warranted to elucidate the specific mechanisms, determine the relevance of these findings to humans, and clarify the suitability of certain food additives for vulnerable populations. It is crucial to note that natural food additives are not inherently superior to synthetic ones in terms of safety. Rigorous evaluation is still warranted before their widespread application in the food industry. Additionally, the potential synergistic effects of commonly used food additives combination in specific food categories on gut microbiota and host metabolism should be investigated to understand their relevance in real-world scenarios.
期刊介绍:
Food Research International serves as a rapid dissemination platform for significant and impactful research in food science, technology, engineering, and nutrition. The journal focuses on publishing novel, high-quality, and high-impact review papers, original research papers, and letters to the editors across various disciplines in the science and technology of food. Additionally, it follows a policy of publishing special issues on topical and emergent subjects in food research or related areas. Selected, peer-reviewed papers from scientific meetings, workshops, and conferences on the science, technology, and engineering of foods are also featured in special issues.