{"title":"Hele-Shaw flow as a singular limit of a Keller-Segel system with nonlinear diffusion","authors":"Antoine Mellet","doi":"10.1007/s00526-024-02826-1","DOIUrl":null,"url":null,"abstract":"<p>We study a singular limit of the classical parabolic-elliptic Patlak-Keller-Segel (PKS) model for chemotaxis with non linear diffusion. The main result is the <span>\\(\\Gamma \\)</span> convergence of the corresponding energy functional toward the perimeter functional. Following recent work on this topic, we then prove that under an energy convergence assumption, the solution of the PKS model converges to a solution of the Hele-Shaw free boundary problem with surface tension, which describes the evolution of the interface separating regions with high density from those with low density. This result complements a recent work by the author with I. Kim and Y. Wu, in which the same free boundary problem is derived from the congested PKS model (which includes a density constraint <span>\\(\\rho \\le 1\\)</span> and a pressure term): It shows that the congestion constraint is not necessary to observe phase separation and surface tension phenomena.</p>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1007/s00526-024-02826-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
We study a singular limit of the classical parabolic-elliptic Patlak-Keller-Segel (PKS) model for chemotaxis with non linear diffusion. The main result is the \(\Gamma \) convergence of the corresponding energy functional toward the perimeter functional. Following recent work on this topic, we then prove that under an energy convergence assumption, the solution of the PKS model converges to a solution of the Hele-Shaw free boundary problem with surface tension, which describes the evolution of the interface separating regions with high density from those with low density. This result complements a recent work by the author with I. Kim and Y. Wu, in which the same free boundary problem is derived from the congested PKS model (which includes a density constraint \(\rho \le 1\) and a pressure term): It shows that the congestion constraint is not necessary to observe phase separation and surface tension phenomena.
我们研究了具有非线性扩散的经典抛物线-椭圆形帕特拉克-凯勒-西格尔(PKS)趋化模型的奇异极限。主要结果是相应的能量函数向周长函数收敛。继最近有关这一主题的工作之后,我们证明了在能量收敛假设下,PKS 模型的解收敛于具有表面张力的 Hele-Shaw 自由边界问题的解,该问题描述了将高密度区域与低密度区域分开的界面的演变。这一结果补充了作者与 I. Kim 和 Y. Wu 的一项最新研究,在这项研究中,同样的自由边界问题是从拥挤的 PKS 模型(其中包括密度约束和压力项)推导出来的:结果表明,要观察相分离和表面张力现象,并不需要拥挤约束。