{"title":"Millmerranones G, a meroterpene isolated from a mangrove-derived fungus <i>Aspergillus</i> sp. GXIMD 03004.","authors":"Guang-Ping Cao, Guo-Qiang Huang, Guang-Ying Chen, Xiang-Xi Yi, Xue-Sheng Wang, Feng-Jiao Wei, Cai-Qiong Zhu, Cheng-Hai Gao, Yong-Hong Liu, Meng Bai","doi":"10.1080/14786419.2024.2402460","DOIUrl":null,"url":null,"abstract":"<p><p>One new meroterpene derivative, millmerranones G (<b>1</b>), and three known analogues (<b>2</b>-<b>4</b>) were identified from the mangrove-derived fungus <i>Aspergillus</i> sp. GXIMD 03004, which was isolated from the leaves of mangrove <i>Acanthus ilicifolius</i> L. collected from Beibu Gulf in China. The structure of <b>1</b> was characterised by a comprehensive interpretation of the NMR spectroscopic and HRESIMS data. The absolute configuration for <b>1</b> was established using experimental and calculated ECD data. The anti-<i>Vibrio</i> activities of all compounds were evaluated, the result showed that compounds <b>1</b> and <b>2</b> has weak activity against <i>Vibrio harveyi</i>.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/14786419.2024.2402460","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
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Abstract
One new meroterpene derivative, millmerranones G (1), and three known analogues (2-4) were identified from the mangrove-derived fungus Aspergillus sp. GXIMD 03004, which was isolated from the leaves of mangrove Acanthus ilicifolius L. collected from Beibu Gulf in China. The structure of 1 was characterised by a comprehensive interpretation of the NMR spectroscopic and HRESIMS data. The absolute configuration for 1 was established using experimental and calculated ECD data. The anti-Vibrio activities of all compounds were evaluated, the result showed that compounds 1 and 2 has weak activity against Vibrio harveyi.
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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