Bioactivity, chemical profiling, and validation of Moringa oleifera cultivated in Suncheon (KR).

IF 1.9 3区 化学 Q3 CHEMISTRY, APPLIED Natural Product Research Pub Date : 2024-11-18 DOI:10.1080/14786419.2024.2426778
Duc Dat Le, Mina Lee
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Abstract

Moringa oleifera is a vegetable rich in vitamins, minerals, and other nutrients that can be used medicinally to enhance human health. This study described how the antioxidative properties of several organs of M. oleifera were used to optimise extraction conditions through their antioxidative capacity. In addition, an analytical approach applying seven marker chemicals was developed and used to construct the chemical profile while simultaneously ascertaining the primary components and their contents in the leaf extract. Of those, the content of quercetin 3-O-malonylglucoside (5) was the greatest, at 12.50 mg/g, followed by neochlorogenic acid (1) at 5.67 mg/g. In a study using molecular docking to target antioxidation, the main constituents of the leaf extract provided some evidence. This was the first study to analyse M. oleifera grown in Suncheon and provide an effective analytical tool to control and verify the quality of this plant species by using standards.

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顺天(韩国)种植的辣木的生物活性、化学成分分析和验证。
油辣木是一种富含维生素、矿物质和其他营养成分的蔬菜,可以通过药用来增强人体健康。本研究介绍了如何利用油茶属植物多个器官的抗氧化能力来优化萃取条件。此外,还开发了一种应用七种标记化学物质的分析方法,用于构建化学概况,同时确定叶提取物中的主要成分及其含量。其中,槲皮素 3-O-丙二酰葡萄糖苷(5)的含量最高,为 12.50 毫克/克,其次是新绿原酸(1),为 5.67 毫克/克。在一项以抗氧化为目标的分子对接研究中,叶提取物的主要成分提供了一些证据。这是首次对顺天生长的 M. oleifera 进行分析的研究,为利用标准控制和验证该植物物种的质量提供了有效的分析工具。
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来源期刊
Natural Product Research
Natural Product Research 化学-医药化学
CiteScore
5.10
自引率
9.10%
发文量
605
审稿时长
2.1 months
期刊介绍: The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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