[Preliminary analysis of risk factors of tinnitus related to female menopause].

X Ma, Y Q Lu, Y X Zhao, L S Yu, W P Bai, R C Lai, L J E
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Abstract

Objective: To investigate the possible pathogenesis and possible risk factors of tinnitus related to female menopause. Methods: From April 2016 to October 2016, 59 female patients with menopausal syndrome were diagnosed in the menopause comprehensive management clinic. Tinnitus and menopause questionnaires were conducted, based on whether having tinnitus, those patients were divided into two groups: tinnitus group and no tinnitus group. Age, body mass index (BMI), Kupperman menopausal index (KMI) score, follicle-stimulating hormone (FSH) level of patients in the two groups were analyzed. Menopausal symptoms, related medical history and possible related factors of tinnitus were statistically analyzed. Results: A total of 59 cases were collected, 22 of which were accompanied by tinnitus. The incidence of idiopathic tinnitus was 35.1% (20/57) because 2 cases of thyroid related tinnitus with clear etiology were removed. Complete data were obtained from 17 of 20 patients with idiopathic tinnitus and 26 of 37 patients without tinnitus. Age, BMI, menopause KMI score, hormone level, menopause symptoms and possible factors related to tinnitus were statistically analyzed between the two groups, and the incidence of headache was statistically different between the two groups (χ2=9.098, P=0.003), but no other factors were statistically significant(P>0.05). The severity of insomnia and tinnitus were further analyzed (χ2=2.841, P=0.417), and there was no significant difference between the two groups. Conclusion: Headache history may be one of the high risk factors for the occurrence of menopausal tinnitus.

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[与女性更年期有关的耳鸣风险因素初步分析]。
目的研究与女性更年期有关的耳鸣的可能发病机制和可能的风险因素。方法:2016年4月至2016年10月,在更年期综合管理门诊确诊更年期综合征女性患者59例。进行耳鸣和更年期问卷调查,根据是否有耳鸣将患者分为两组:耳鸣组和无耳鸣组。分析两组患者的年龄、体重指数(BMI)、库珀曼绝经指数(KMI)评分、促卵泡激素(FSH)水平。对更年期症状、相关病史和耳鸣的可能相关因素进行了统计分析。结果共收集到 59 例病例,其中 22 例伴有耳鸣。特发性耳鸣的发生率为 35.1%(20/57),因为有 2 例病因明确的甲状腺相关性耳鸣病例被排除在外。在 20 例特发性耳鸣患者中,有 17 例获得了完整的数据,在 37 例无耳鸣患者中,有 26 例获得了完整的数据。对两组患者的年龄、体重指数(BMI)、更年期 KMI 评分、激素水平、更年期症状以及与耳鸣相关的可能因素进行了统计分析,两组患者的头痛发生率有统计学差异(χ2=9.098,P=0.003),但其他因素均无统计学意义(P>0.05)。进一步分析失眠和耳鸣的严重程度(χ2=2.841,P=0.417),两组间无显著差异。结论头痛史可能是更年期耳鸣发生的高危因素之一。
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