The Impact of a Medication Therapy Management Service on the Outcomes of Hypertension Treatment Follow-Up Care in an Ethiopian Tertiary Hospital: A Pre-Post Interventional Study.

IF 2.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Clinical Medicine Insights. Cardiology Pub Date : 2024-09-18 eCollection Date: 2024-01-01 DOI:10.1177/11795468241274720
Belachew Bulo, Minyahil Woldu, Alemseged Beyene, Desalew Mekonnen, Ephrem Engidawork
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Abstract

Background: According to a report from the WHO, an estimated 1.13 billion people worldwide have hypertension. Medication therapy management (MTM) service is a clinical service based on the theoretical and methodological framework of pharmaceutical care practice, which aims to ensure the best therapeutic outcomes for the patient by identifying, preventing, and resolving drug therapy problems (DTPs).

Purpose: The goal of this study was to determine the impact of MTM on hypertension management in Ethiopia.

Methods: A pre-post interventional study design was used. Descriptive statistics, linear regression, and logistic regressions were employed to present and analyze data.

Results: The final analysis included 279 patients out of 304, with a 7.8% attrition rate. The prevalence of drug therapy problems (DTPs) reduced from 63.4% at baseline to 31.5% during the post-intervention phase. Polypharmacy (AOR = 2.46; 95% CI: 1.27-4.77) and complications (AOR = 0.52; 95% CI: 0.27-0.99) were substantially associated with DTPs at the start of the study. The MTM resulted in a significant reduction in mean systolic blood pressure (SBP) (AOR = 5.31, 95% CI (3.50-7.11), P < .001), as well as a significant increase (P < .001) in the number of study patients who reached a target BP. At the end of the MTM intervention, non-adherence was linked with DTP (AOR = 2.40; 95% CI: 1.33-4.334) and living outside Addis Ababa (AOR = 1.73; 95% CI: 1.38-1.88). On average, treatment satisfaction was 86.55% (+SD) 10.34.

Conclusion: To resolve DTPs and improve clinical outcomes, the MTM service was critical. The majority of patients were found to be compliant with a high treatment satisfaction score.

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埃塞俄比亚一家三级医院的药物治疗管理服务对高血压治疗后续护理结果的影响:介入治疗前研究
背景:根据世界卫生组织的报告,全球估计有 11.3 亿人患有高血压。药物治疗管理(MTM)服务是一种基于药物治疗实践的理论和方法框架的临床服务,旨在通过识别、预防和解决药物治疗问题(DTPs),确保患者获得最佳治疗效果:方法:采用前后干预研究设计。采用描述性统计、线性回归和逻辑回归来呈现和分析数据:最终分析包括 304 名患者中的 279 名,自然减员率为 7.8%。药物治疗问题(DTPs)的发生率从基线阶段的 63.4% 降至干预后阶段的 31.5%。多药治疗(AOR = 2.46;95% CI:1.27-4.77)和并发症(AOR = 0.52;95% CI:0.27-0.99)与研究开始时的药物治疗问题密切相关。MTM 显著降低了平均收缩压(SBP)(AOR = 5.31,95% CI (3.50-7.11),P P 结论:要解决 DTP 问题并改善临床疗效,MTM 服务至关重要。大多数患者对治疗的依从性和满意度都很高。
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来源期刊
Clinical Medicine Insights. Cardiology
Clinical Medicine Insights. Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
5.20
自引率
3.30%
发文量
16
审稿时长
8 weeks
期刊最新文献
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