Massimiliano Degani, Andrea Paolini, Amanda Bianchi, Roberto Tamburro, Lorenzo Di Matteo, Charlotte Sandersen, Angela Briganti
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引用次数: 0
Abstract
Objective: To compare the perioperative analgesic effect of lateral versus latero-ventral quadratus lumborum block (QLB) in dogs undergoing laparoscopic ovariectomy.
Study design: Randomized, blinded clinical study.
Animals: A total of 15 client-owned female dogs undergoing laparoscopic ovariectomy.
Methods: Animals were randomly assigned to receive a bilateral QLB, performed with 0.3 mL kg-1 ropivacaine 0.5%, either with lateral (group LQLB, n = 7) or latero-ventral approach (group LVQLB, n = 7). Dogs were premedicated intramuscularly with methadone 0.2 mg kg-1 and dexmedetomidine 3 μg kg-1. General anaesthesia was induced intravenously (IV) with propofol and maintained with isoflurane. Cardiovascular and respiratory variables were continuously monitored and recorded every 5 minutes during surgery. Fentanyl 3 μg kg-1 was administered IV if there was a 20% increase in heart rate and/or mean arterial pressure from previous values recorded 5 minutes before. Meloxicam 0.2 mg kg-1 was administered IV to all dogs during recovery. The short-form of the Glasgow Composite Pain Scale was used hourly for 8 hours post-QLB. Methadone 0.2 mg kg-1 was administered IV when pain score was ≥ 6/24. A chi-square test compared the number of dogs requiring intraoperative rescue fentanyl. A Friedman test with a Dunn's post hoc was used to evaluate the trend in postoperative pain scores within each group, and a Mann-Whitney U test compared scores between the groups at each time point; p < 0.05.
Results: Significantly fewer dogs required intraoperative rescue fentanyl in group LQLB than in group LVQLB. No dog required postoperative rescue methadone, and there were no significant differences in pain scores.
Conclusions and clinical relevance: Bilateral QLB performed with lateral approach reduced the number of dogs requiring intraoperative rescue analgesia in comparison with the latero-ventral approach. No differences were detected postoperatively, possibly owing to the confounding effects of methadone, dexmedetomidine and meloxicam.
期刊介绍:
Veterinary Anaesthesia and Analgesia is the official journal of the Association of Veterinary Anaesthetists, the American College of Veterinary Anesthesia and Analgesia and the European College of Veterinary Anaesthesia and Analgesia. Its purpose is the publication of original, peer reviewed articles covering all branches of anaesthesia and the relief of pain in animals. Articles concerned with the following subjects related to anaesthesia and analgesia are also welcome:
the basic sciences;
pathophysiology of disease as it relates to anaesthetic management
equipment
intensive care
chemical restraint of animals including laboratory animals, wildlife and exotic animals
welfare issues associated with pain and distress
education in veterinary anaesthesia and analgesia.
Review articles, special articles, and historical notes will also be published, along with editorials, case reports in the form of letters to the editor, and book reviews. There is also an active correspondence section.