Development and validation of a functional ability index for older adults: a multicohort study.

IF 6 2区 医学 Q1 GERIATRICS & GERONTOLOGY Age and ageing Pub Date : 2024-10-01 DOI:10.1093/ageing/afae231
Yi Chang, Suman Sapkota, Bipin Thapa, Lina Ma, Linghui Sheng, Chaodong Wang, Jagadish K Chhetri, Piu Chan
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Abstract

Background: The aim of this study was to develop and validate a functional ability index (FAI) that incorporates aspects of intrinsic capacity and environmental factors of older individuals based on the World Health Organization framework of healthy ageing.

Methods: Data of 7016 participants ≥60 years participating in the baseline survey of China Health and Retirement Longitudinal Study was used for the development and internal validation of the FAI. External validation was performed in a separate cohort of 1295 older individuals aged ≥60 years. Functional independency was considered the primary outcome and additional proxies of healthy ageing were considered as secondary outcomes. Cluster dendrogram was used to identify the distinct hierarchical clusters of all included variables for inclusion in the FAI. Backward elimination logistic regression model was implemented to identify the most significant variables associated with independency to be included in the FAI.

Results: The FAI score ranged from 0 to 19 and individuals having FAI ≥ 12 were more likely to be independent and at lower risk of negative outcomes. For each unit increase in the FAI the risk of having independency increased by 30%-58% cross-sectionally in the two cohorts, whilst the 2-year risk of independency increased by 20%. The FAI demonstrated a C-statistic of 0.73 (95% confidence interval, 0.72 and 0.75) for the primary outcome.

Conclusions: The FAI we developed effectively measured the functional ability status of community dwelling older individuals. FAI could serve as a tool for evaluating older individual's functional ability in routine health assessment.

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老年人功能能力指数的开发与验证:一项多队列研究。
研究背景本研究的目的是在世界卫生组织健康老龄化框架的基础上,开发并验证一种包含老年人内在能力和环境因素的功能能力指数(FAI):方法:利用参加中国健康与退休纵向研究基线调查的 7016 名年龄≥60 岁的参与者的数据,对 FAI 进行开发和内部验证。在1295名年龄≥60岁的老年人组成的独立队列中进行了外部验证。功能独立性被视为主要结果,健康老龄化的其他代用指标被视为次要结果。聚类树枝图用于识别所有纳入 FAI 的变量的不同层次聚类。采用后向消除逻辑回归模型来确定与独立相关的最重要变量,并将其纳入 FAI:FAI 分值介于 0 到 19 之间,FAI ≥ 12 的个体更有可能是独立的,且出现负面结果的风险较低。在两个队列中,FAI每增加一个单位,独立的风险就会增加30%-58%,而两年后独立的风险则会增加20%。FAI 对主要结果的 C 统计量为 0.73(95% 置信区间为 0.72 和 0.75):我们开发的 FAI 能有效测量社区老年人的功能能力状况。FAI可作为常规健康评估中评估老年人功能能力的工具。
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来源期刊
Age and ageing
Age and ageing 医学-老年医学
CiteScore
9.20
自引率
6.00%
发文量
796
审稿时长
4-8 weeks
期刊介绍: Age and Ageing is an international journal publishing refereed original articles and commissioned reviews on geriatric medicine and gerontology. Its range includes research on ageing and clinical, epidemiological, and psychological aspects of later life.
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