Myriam Lesage, Karin Cinalioglu, Sabrina Chan, Sanjeev Kumar, Tarek Rajji, Ashley Melichercik, Carmen Desjardins, Jess Friedland, Amer Burhan, Sarah Colman, Li Chu, Simon Davies, Peter Derkach, Sarah Elmi, Philip Gerretsen, Ariel Graff-Guerrero, Maria Hussain, Zahinoor Ismail, Donna Kim, Linda Krisman, Rola Moghabghab, Benoit H Mulsant, Bruce G Pollock, Aviva Rostas, Lisa Van Bussel, Soham Rej
{"title":"Are Opioids Agitating? A Data Analysis of Baseline Data from the STAN Study.","authors":"Myriam Lesage, Karin Cinalioglu, Sabrina Chan, Sanjeev Kumar, Tarek Rajji, Ashley Melichercik, Carmen Desjardins, Jess Friedland, Amer Burhan, Sarah Colman, Li Chu, Simon Davies, Peter Derkach, Sarah Elmi, Philip Gerretsen, Ariel Graff-Guerrero, Maria Hussain, Zahinoor Ismail, Donna Kim, Linda Krisman, Rola Moghabghab, Benoit H Mulsant, Bruce G Pollock, Aviva Rostas, Lisa Van Bussel, Soham Rej","doi":"10.3233/ADR-240025","DOIUrl":null,"url":null,"abstract":"<p><p> Agitation, a common dementia symptom often arising from untreated pain, lacks comprehensive research on its connection with opioids prescribed for long-term pain. This study investigated the relationship between opioid use and agitation in dementia patients. Participants (<i>n</i> = 188) were categorized into opioid, acetaminophen PRN, or no-pain medication groups. Despite higher reported pain levels in the opioid group, no significant differences in agitation were observed among the groups. In conclusion, opioid use for pain management in older adults with dementia did not significantly impact agitation, emphasizing the ongoing importance of proper pain management in improving dementia care and addressing agitation in this population.</p>","PeriodicalId":73594,"journal":{"name":"Journal of Alzheimer's disease reports","volume":"8 1","pages":"1297-1300"},"PeriodicalIF":2.8000,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11491946/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Alzheimer's disease reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3233/ADR-240025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Agitation, a common dementia symptom often arising from untreated pain, lacks comprehensive research on its connection with opioids prescribed for long-term pain. This study investigated the relationship between opioid use and agitation in dementia patients. Participants (n = 188) were categorized into opioid, acetaminophen PRN, or no-pain medication groups. Despite higher reported pain levels in the opioid group, no significant differences in agitation were observed among the groups. In conclusion, opioid use for pain management in older adults with dementia did not significantly impact agitation, emphasizing the ongoing importance of proper pain management in improving dementia care and addressing agitation in this population.
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