Multicentric Retrospective Study on Safety and Efficacy of a Novel Injectable Poly-l-Lactic Acid for Buttocks Recontouring.

Abstract

Background: Poly-l-lactic acid (PLLA) injectables have gained increasing attention in aesthetic medicine due to their biocompatibility and long-lasting effects. Although their primary application centers around facial rejuvenation, their potential for off-label use in other body areas has been investigated, demonstrating promising outcomes in terms of both efficacy and safety.

Aim: This study aims to assess the safety and efficacy of a novel 630 mg PLLA-based filler (GANA X), in buttocks treatment.

Methods: Six physicians treated 51 patients for buttock aesthetic treatment across six different medical facilities in Italy. A survey was filled by both physicians and patients regarding treatment safety, efficacy, and change in quality of life.

Results: We reported minor or mild adverse events, self-resolving within the next few days. Both physicians and patients confirmed notable aesthetic improvements following treatment, varying from moderate to significant enhancement. These effects endured throughout follow-up visits spanning up to 24 months. Patient-reported outcomes indicated elevated self-esteem and improved quality of life posttreatment.

Conclusions: The high level of satisfaction reported by both physicians and patients highlights the efficacy and tolerability of GANA X filler for buttocks treatment, encouraging their use and research for off-label body areas.