[Unilateral arytenoid chondroplasty combined with minimally invasive mucosal flap plasty for bilateral vocal cord paralysis--clinical analysis of 66 cases].

J Deng, F Zhang, X M Wu, D Wang, L Chen, R Q Ma, Z F Wang, X L Zhu, W B Lei
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引用次数: 0

Abstract

Objective: To analyze the efficacy of unilateral arytenoid chondroplasty combined with minimally invasive mucosal flap plasty in the management bilateral vocal cord paralysis. Methods: A total of 66 patients with bilateral vocal cord paralysis hospitalized in the First Hospital of Sun Yat-sen University from January 2018 to December 2023 were retrospectively analyzed, among whom there were 8 males and 58 females, with ages ranging from 35 to 86 years old(mean age (57.8±11.6) years). All patients underwent suspension laryngoscopic CO2 laser unilateral arytenoid chondroplasty and mucosal flap under general anesthesia. Postoperative follow-up period extended from 6 months to 6 years, with a median duration of 28 months. The study compared the degree of dyspnea and voice quality (subjective and objective evaluation) of the patients pre- and post-operatively, and analyzed the clinical differences between patients with and without preoperative or intraoperative tracheotomy, the extubation rate of tracheotomized patients, the recurrence rate, and the complication rate. Continuous variables conforming to normal distribution were tested by t-test and categorical variables by χ² test,the Wilcoxon rank-sum test was used to analyze the improvement in dyspnea before and after surgery. Results: Compared with the preoperative period, 59 patients showed improvement in postoperative dyspnea (U=161.5, P<0.01); there was no significant difference in voice disorder index 10, subjective auditory-perceptual assessment, and maximal vocalization time (P>0.05), all of which remained within the relative normal range. Tracheotomy was performed in 32 out of 66 patients, with predominantly degree Ⅲ- dyspnea (46.9%, 15/32), including 26 patients with preoperative tracheotomy and 6 patients with intraoperative tracheotomy. Among the 34 patients who did not undergo tracheotomy, the majority presented with degree Ⅱ-dyspnea (82.4%, 28/34). All patients achieved successful extubation following surgery, with a mean median time to extubation of 1 month. Conclusions: The combination of unilateral arytenoid chondroplasty and minimally invasive mucosal flap plasty represents a refined and effective therapeutic approach for bilateral vocal cord paralysis. This minimally invasive technique has the potential to reduce the rate of tracheotomy.

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[单侧杓状软骨成形术联合微创粘膜瓣成形术治疗双侧声带麻痹--66 例临床分析]。
目的分析单侧杓状软骨成形术联合微创粘膜瓣成形术治疗双侧声带麻痹的疗效。方法:回顾性分析2018年1月-2023年12月在中山大学附属第一医院住院治疗的双侧声带麻痹患者共66例,其中男8例,女58例,年龄35~86岁(平均年龄(57.8±11.6)岁)。所有患者均在全身麻醉下接受了悬吊喉镜下二氧化碳激光单侧杓状软骨成形术和粘膜瓣手术。术后随访期从 6 个月到 6 年不等,中位随访期为 28 个月。研究比较了患者术前和术后的呼吸困难程度和语音质量(主观和客观评价),分析了术前或术中气管切开患者与未切开患者的临床差异、气管切开患者的拔管率、复发率和并发症发生率。符合正态分布的连续变量采用t检验,分类变量采用χ²检验,手术前后呼吸困难改善情况采用Wilcoxon秩和检验。结果与术前相比,59 例患者术后呼吸困难有所改善(U=161.5,PP>0.05),且均保持在相对正常范围内。66 例患者中有 32 例进行了气管切开术,以Ⅲ度呼吸困难为主(46.9%,15/32),其中 26 例患者术前进行了气管切开术,6 例患者术中进行了气管切开术。在 34 名未进行气管切开术的患者中,大多数患者表现为Ⅱ度呼吸困难(82.4%,28/34)。所有患者术后均成功拔管,平均拔管时间中位数为 1 个月。结论单侧杓状软骨成形术和微创粘膜瓣成形术的结合是治疗双侧声带麻痹的一种精细有效的方法。这种微创技术有可能降低气管切开率。
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