Clinical profile of patients with surgical brain abscesses and etiology in a reference hospital.

IF 1.4 4区 医学 Q4 INFECTIOUS DISEASES Journal of Infection in Developing Countries Pub Date : 2024-09-30 DOI:10.3855/jidc.18729
Ana Laura Calderón-Garcidueñas, Erika Gayón-Lombardo, Alejandro Salazar-Félix, Daniel Rocandio-Hernández, Martha Lilia Tena-Suck, Carlos Sánchez-Garibay
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Abstract

Introduction: The annual incidence of brain abscesses is 1-2% in developed countries and up to 8% in developing countries. Our aim was to describe the profile and etiological agents of patients with surgical brain infections according to their nosological diagnosis on admission, and to analyze whether the initial diagnosis influenced the neurological deficit at discharge.

Methodology: This was an observational study with convenience sampling. All surgical cases operated between January 2017 and February 2022 with a final diagnosis of an infectious process were included. Three groups were analyzed according to admission diagnosis: a) infection, b) neoplasia, and c) miscellaneous. The time before admission, final histological diagnosis, etiological agent, length of hospital stay, and secondary neurological deficits were investigated. Descriptive and comparative statistics were used.

Results: 24 cases, including 18 (75%) men and 6 (25%) women, of ages 19 to 61 years (average 43.7 years) were studied. Nosological diagnoses on admission were infection in 9 (37.5%) patients, cerebral neoplasia in 9 (37.5%) patients, and miscellaneous diagnoses in 6 (25%) patients. Among the miscellaneous, neoplastic, and infectious groups, 33.3%, 33.3%, and 22.2% of patients were discharged with some neurological deficits with overall neurological morbidity and mortality of 29.6% and 8%, respectively. The etiological agents were Mycobacterium tuberculosis (16.6%), Streptococcus sp. (13%), Morganella morganii (8.7%), Nocardia sp. (4.3%), Cryptococcus sp. (4.3%), and Klebsiella sp. (4.3%).

Conclusions: Nosological diagnosis on admission did not influence the percentage of patients with neurological deficits in our study. Mycobacterium was the most frequent etiological agent.

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一家参考医院脑脓肿手术患者的临床概况和病因。
导言:在发达国家,脑脓肿的年发病率为 1-2%,而在发展中国家则高达 8%。我们的目的是根据入院时的病理诊断,描述外科脑部感染患者的概况和病原体,并分析初步诊断是否会影响出院时的神经功能缺损:这是一项方便取样的观察性研究。纳入2017年1月至2022年2月期间所有最终诊断为感染过程的手术病例。根据入院诊断分为三组进行分析:a) 感染;b) 肿瘤;c) 其他。对入院前时间、最终组织学诊断、病原体、住院时间和继发性神经功能缺损进行了调查。结果:研究对象共 24 例,其中男性 18 例(75%),女性 6 例(25%),年龄在 19 岁至 61 岁之间(平均 43.7 岁)。入院诊断为感染的有 9 例(37.5%),脑肿瘤的有 9 例(37.5%),其他诊断的有 6 例(25%)。在杂项诊断、肿瘤和感染组中,分别有 33.3%、33.3% 和 22.2% 的患者出院时有一些神经功能缺损,神经系统总发病率和死亡率分别为 29.6% 和 8%。病原体为结核分枝杆菌(16.6%)、链球菌(13%)、摩根氏菌(8.7%)、诺卡氏菌(4.3%)、隐球菌(4.3%)和克雷伯氏菌(4.3%):结论:在我们的研究中,入院时的病原学诊断并不影响神经功能障碍患者的比例。分枝杆菌是最常见的病原体。
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来源期刊
CiteScore
3.70
自引率
5.30%
发文量
239
审稿时长
4-8 weeks
期刊介绍: The Journal of Infection in Developing Countries (JIDC) is an international journal, intended for the publication of scientific articles from Developing Countries by scientists from Developing Countries. JIDC is an independent, on-line publication with an international editorial board. JIDC is open access with no cost to view or download articles and reasonable cost for publication of research artcles, making JIDC easily availiable to scientists from resource restricted regions.
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