{"title":"Cage-like micro-scaffolds fabricated by DLW method for cell investigation","authors":"A.V. Pisarenko , D.S. Burkatovskii , D.A. Kolymagin , D.A. Chubich , V.I. Borshchevskiy , A.G. Vitukhnovsky","doi":"10.1016/j.photonics.2024.101321","DOIUrl":null,"url":null,"abstract":"<div><div>This paper focuses on the use of direct laser writing method in fabricating three-dimensional biocompatible scaffolds that emulate the extracellular matrix. The interaction between HEK 293 cells and these cage-like scaffolds, particularly the effect of pore size on cell invasion, is explored in detail. Our study underscores the influence of scaffold architecture on cellular behavior and highlights the potential of direct laser writing technology in creating complex 3D scaffolds. The insights gleaned from this research could be invaluable in future applications such as tissue engineering, regenerative medicine, and drug delivery.</div></div>","PeriodicalId":49699,"journal":{"name":"Photonics and Nanostructures-Fundamentals and Applications","volume":"62 ","pages":"Article 101321"},"PeriodicalIF":2.5000,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photonics and Nanostructures-Fundamentals and Applications","FirstCategoryId":"101","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1569441024000968","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
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Abstract
This paper focuses on the use of direct laser writing method in fabricating three-dimensional biocompatible scaffolds that emulate the extracellular matrix. The interaction between HEK 293 cells and these cage-like scaffolds, particularly the effect of pore size on cell invasion, is explored in detail. Our study underscores the influence of scaffold architecture on cellular behavior and highlights the potential of direct laser writing technology in creating complex 3D scaffolds. The insights gleaned from this research could be invaluable in future applications such as tissue engineering, regenerative medicine, and drug delivery.
期刊介绍：
This journal establishes a dedicated channel for physicists, material scientists, chemists, engineers and computer scientists who are interested in photonics and nanostructures, and especially in research related to photonic crystals, photonic band gaps and metamaterials. The Journal sheds light on the latest developments in this growing field of science that will see the emergence of faster telecommunications and ultimately computers that use light instead of electrons to connect components.
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