Neighborhood Socioeconomic Deprivation is Associated with Worse Outcomes in Pediatric Kidney Transplant Recipients.

IF 8.5 1区 医学 Q1 UROLOGY & NEPHROLOGY Clinical Journal of the American Society of Nephrology Pub Date : 2024-10-31 DOI:10.2215/CJN.0000000592
Chloe E Douglas, Miranda C Bradford, Rachel M Engen, Yue-Harn Ng, Aaron Wightman, Reya Mokiao, Sharon Bartosh, André A S Dick, Jodi M Smith
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邻里社会经济贫困与小儿肾移植受者的不良预后有关。
背景:健康的社会决定因素影响着儿童的移植过程。我们描述了美国儿科肾移植受者的社区社会经济贫困程度、移植特征和移植存活率之间的关系:方法:美国受者在来自社会经济条件较差社区的受者中,24%(N=110)的受者被认定为黑人,而在来自社会经济条件较差社区的受者中,12%(N=383)的受者被认定为黑人。在社会经济条件较差的社区,自认为是西班牙裔受助者的比例要高得多(67%,N=311),而在社会经济条件较差的社区,自认为是西班牙裔受助者的比例要低得多(17%,N=562)。在对基本协变量、种族和民族以及保险状况进行调整后,高社会经济贫困社区的受者与低社会经济贫困社区的受者相比,移植物丢失的风险高 55%(aHR 1.55,95% CI:1.24,1.94),几率低 59%(aOR 0.41,95% CI:0.30,0.56),而抢先移植的几率降低了 8%(aOR 0.92,95% CI:0.72,1.19),但无统计学意义。在对基本协变量、种族和民族以及保险状况进行调整后,来自中等社会经济贫困社区的受者与来自低社会经济贫困社区的受者相比,移植物丢失的风险高 41%(aHR 1.41,95% CI:1.25,1.60),几率低 27%(aOR 0.73,95% CI:0.66,0.81),而接受抢先移植的几率则低 11%(aOR 0.89,95% CI:0.80,0.99):结论:来自社会经济条件较差社区的儿童移植存活率较低,对抢先移植和活体移植的利用率也较低。这些发现表明,小儿肾移植中存在不公平现象,需要进一步干预。
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来源期刊
CiteScore
12.20
自引率
3.10%
发文量
514
审稿时长
3-6 weeks
期刊介绍: The Clinical Journal of the American Society of Nephrology strives to establish itself as the foremost authority in communicating and influencing advances in clinical nephrology by (1) swiftly and effectively disseminating pivotal developments in clinical and translational research in nephrology, encompassing innovations in research methods and care delivery; (2) providing context for these advances in relation to future research directions and patient care; and (3) becoming a key voice on issues with potential implications for the clinical practice of nephrology, particularly within the United States. Original manuscript topics cover a range of areas, including Acid/Base and Electrolyte Disorders, Acute Kidney Injury and ICU Nephrology, Chronic Kidney Disease, Clinical Nephrology, Cystic Kidney Disease, Diabetes and the Kidney, Genetics, Geriatric and Palliative Nephrology, Glomerular and Tubulointerstitial Diseases, Hypertension, Maintenance Dialysis, Mineral Metabolism, Nephrolithiasis, and Transplantation.
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