{"title":"Correction: Filtration Markers as Predictors of ESRD and Mortality: Individual Participant Data Meta-Analysis.","authors":"","doi":"10.2215/CJN.0000000661","DOIUrl":"https://doi.org/10.2215/CJN.0000000661","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Shape, Size, and Spatial Relationships: Peritubular Capillary Features in Kidney Fibrosis and Disease Progression.","authors":"Cynthia C Nast","doi":"10.2215/CJN.0000000647","DOIUrl":"https://doi.org/10.2215/CJN.0000000647","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring Unintended Consequences from the Prospective Payment System Transitional Drug Add-On Payment Adjustment to Refine Program Enhancement Strategies.","authors":"Donald Andrew Molony, Dia Rose Waguespack","doi":"10.2215/CJN.0000000649","DOIUrl":"https://doi.org/10.2215/CJN.0000000649","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Do Federally Qualified Health Centers Improve ESKD Readiness in Nonelderly Underserved Populations?","authors":"Ileana V Barrientos, Kevin F Erickson","doi":"10.2215/CJN.0000000648","DOIUrl":"https://doi.org/10.2215/CJN.0000000648","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vishnupriyadevi Parvathareddy, Anitha Vijayan, Ashley Penrod, Gon Lam, Leslie P Wong
{"title":"Advanced Practice Provider (APP) Residency Program to Strengthen the Kidney Health Workforce.","authors":"Vishnupriyadevi Parvathareddy, Anitha Vijayan, Ashley Penrod, Gon Lam, Leslie P Wong","doi":"10.2215/CJN.0000000660","DOIUrl":"https://doi.org/10.2215/CJN.0000000660","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seung Min Chung, Inha Jung, Da Young Lee, So Young Park, Ji Hee Yu, Jun Sung Moon, Ji A Seo, Kyung-do Han, Nan Hee Kim
Background: The effects of glomerular hyperfiltration (GHF) on cardiovascular disease (CVD) risk in patients with type 2 diabetes mellitus (T2DM) were explored.
Methods: This retrospective cohort study enrolled 1,952,053 patients with type 2 diabetes mellitus from the Korean National Health Insurance Service database between 2015 and 2016. Based on age- and sex-specific estimated glomerular filtration rate (eGFR) percentiles, patients were classified into five groups: <5 (low filtration), 5-40, 40-60, 60-95, and >95 (GHF). Patients with incident cardiovascular disease (CVD) (myocardial infarction [MI], stroke, and hospitalization for heart failure [HF]) were followed up until December 2022.
Results: CVD occurred in 214,111 patients (11%). The incidence rates were 36.1, 20.8, 18.3, 18.7, and 19.3 per 1000 person-years for the eGFR groups, respectively. Low filtration (hazard ratio [HR] = 1.56, 95% confidence intervals [CI] 1.53-1.59) and GHF (HR = 1.13, 95% CI 1.10-1.15) were associated with higher CVD risk adjusted for covariates than that of the eGFR 40-60 percentile, showing an inverted J-shaped relationship. GHF was associated with a higher risk of MI (HR = 1.06, 95% CI 1.01-1.11) and HF (HR = 1.17, 95% CI 1.14-1.20) and with a higher risk of stroke. eGFR was associated with CVD risk across subgroups of age, sex, obesity, hypertension, and dyslipidemia. The impact of GHF on CVD may be greater in younger patients (HR = 1.30, 1.17, and 1.05 in <40, 40-60, and ≥65 years old, respectively).
Conclusions: GHF was associated with CVD, particularly MI and HF. Screening for GHF in the early stages of T2DM may be beneficial.
{"title":"Effect of Glomerular Hyperfiltration on Incident Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus.","authors":"Seung Min Chung, Inha Jung, Da Young Lee, So Young Park, Ji Hee Yu, Jun Sung Moon, Ji A Seo, Kyung-do Han, Nan Hee Kim","doi":"10.2215/CJN.0000000618","DOIUrl":"https://doi.org/10.2215/CJN.0000000618","url":null,"abstract":"<p><strong>Background: </strong>The effects of glomerular hyperfiltration (GHF) on cardiovascular disease (CVD) risk in patients with type 2 diabetes mellitus (T2DM) were explored.</p><p><strong>Methods: </strong>This retrospective cohort study enrolled 1,952,053 patients with type 2 diabetes mellitus from the Korean National Health Insurance Service database between 2015 and 2016. Based on age- and sex-specific estimated glomerular filtration rate (eGFR) percentiles, patients were classified into five groups: <5 (low filtration), 5-40, 40-60, 60-95, and >95 (GHF). Patients with incident cardiovascular disease (CVD) (myocardial infarction [MI], stroke, and hospitalization for heart failure [HF]) were followed up until December 2022.</p><p><strong>Results: </strong>CVD occurred in 214,111 patients (11%). The incidence rates were 36.1, 20.8, 18.3, 18.7, and 19.3 per 1000 person-years for the eGFR groups, respectively. Low filtration (hazard ratio [HR] = 1.56, 95% confidence intervals [CI] 1.53-1.59) and GHF (HR = 1.13, 95% CI 1.10-1.15) were associated with higher CVD risk adjusted for covariates than that of the eGFR 40-60 percentile, showing an inverted J-shaped relationship. GHF was associated with a higher risk of MI (HR = 1.06, 95% CI 1.01-1.11) and HF (HR = 1.17, 95% CI 1.14-1.20) and with a higher risk of stroke. eGFR was associated with CVD risk across subgroups of age, sex, obesity, hypertension, and dyslipidemia. The impact of GHF on CVD may be greater in younger patients (HR = 1.30, 1.17, and 1.05 in <40, 40-60, and ≥65 years old, respectively).</p><p><strong>Conclusions: </strong>GHF was associated with CVD, particularly MI and HF. Screening for GHF in the early stages of T2DM may be beneficial.</p>","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nidhi Ghildayal, Jingyao Hong, Yi Liu, Yiting Li, Samuel G Cockey, Nicole M Ali, Aarti Mathur, Babak Orandi, Dorry L Segev, Mara McAdams-DeMarco
{"title":"Weight Loss Intentionality and Frailty are Associated with Pre-Kidney Transplant Outcomes.","authors":"Nidhi Ghildayal, Jingyao Hong, Yi Liu, Yiting Li, Samuel G Cockey, Nicole M Ali, Aarti Mathur, Babak Orandi, Dorry L Segev, Mara McAdams-DeMarco","doi":"10.2215/CJN.0000000604","DOIUrl":"10.2215/CJN.0000000604","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-12-12DOI: 10.2215/CJN.0000000629
Kelsey Drewry
{"title":"An Early Assessment of the ESKD Treatment Choices Model on Kidney Transplant Waitlisting.","authors":"Kelsey Drewry","doi":"10.2215/CJN.0000000629","DOIUrl":"10.2215/CJN.0000000629","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"9-11"},"PeriodicalIF":8.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-09-19DOI: 10.2215/CJN.0000000000000564
Clara Schott, Victoria Lebedeva, Cambrie Taylor, Saeed Abumelha, Pavel S Roshanov, Dervla M Connaughton
{"title":"Utility of Genetic Testing in Adults with CKD: A Systematic Review and Meta-Analysis.","authors":"Clara Schott, Victoria Lebedeva, Cambrie Taylor, Saeed Abumelha, Pavel S Roshanov, Dervla M Connaughton","doi":"10.2215/CJN.0000000000000564","DOIUrl":"10.2215/CJN.0000000000000564","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"20 1","pages":"101-115"},"PeriodicalIF":8.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-12-16DOI: 10.2215/CJN.0000000628
Akinlolu O Ojo
{"title":"Surrogate Clinical End Points in Studies of APOL1-Associated Kidney Disease: Just in Time.","authors":"Akinlolu O Ojo","doi":"10.2215/CJN.0000000628","DOIUrl":"10.2215/CJN.0000000628","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"3-5"},"PeriodicalIF":8.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}