Smelling a concept

IF 21.2 1区医学 Q1 NEUROSCIENCES Nature neuroscience Pub Date : 2024-11-04 DOI:10.1038/s41593-024-01803-3

Leonie Welberg

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嗅觉概念

尽管功能成像研究表明，气味会激活人的梨状皮层、杏仁核、内侧皮层和海马体，但气味的哪些方面（如身份和价值）在大脑的哪个部位编码仍不清楚。Kehl 等人记录了人类这四个脑区的数千个神经元，要求他们对 15 种不同气味进行评价（喜欢或不喜欢）和识别。每个区域都有大量神经元根据气味特征改变其发射率，而且气味特征可以从神经元活动中解码。有趣的是，梨状皮层和海马中的神经元分别编码实际（化学）和感知的气味特征。在杏仁核中，气味调节神经元对 "喜欢的 "气味的反应比对 "不喜欢的 "气味的反应要大，而且反应与气味价值评级相关。值得注意的是，所有四个区域都含有神经元，这些神经元对与气味一致的视觉图像（例如一块甘草）的反应会改变其发射，这些神经元群与气味调节神经元有部分重叠。在梨状皮层和杏仁核中，一些神经元还对代表气味的书面文字（如 "甘草"）和相关气味（如茴香）做出反应，这表明这些早期嗅觉处理区域进行了概念编码--这是一个有趣的概念，需要进一步研究：原始参考文献：Nature 634, 626-634 (2024)

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来源期刊

Nature neuroscience 医学-神经科学

CiteScore

38.60

自引率

1.20%

发文量

212

审稿时长

1 months

期刊介绍： Nature Neuroscience, a multidisciplinary journal, publishes papers of the utmost quality and significance across all realms of neuroscience. The editors welcome contributions spanning molecular, cellular, systems, and cognitive neuroscience, along with psychophysics, computational modeling, and nervous system disorders. While no area is off-limits, studies offering fundamental insights into nervous system function receive priority. The journal offers high visibility to both readers and authors, fostering interdisciplinary communication and accessibility to a broad audience. It maintains high standards of copy editing and production, rigorous peer review, rapid publication, and operates independently from academic societies and other vested interests. In addition to primary research, Nature Neuroscience features news and views, reviews, editorials, commentaries, perspectives, book reviews, and correspondence, aiming to serve as the voice of the global neuroscience community.

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