Data-centric automated approach to predict autism spectrum disorder based on selective features and explainable artificial intelligence.

IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Frontiers in Computational Neuroscience Pub Date : 2024-10-21 eCollection Date: 2024-01-01 DOI:10.3389/fncom.2024.1489463
Asma Aldrees, Stephen Ojo, James Wanliss, Muhammad Umer, Muhammad Attique Khan, Bayan Alabdullah, Shtwai Alsubai, Nisreen Innab
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Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by notable challenges in cognitive function, understanding language, recognizing objects, interacting with others, and communicating effectively. Its origins are mainly genetic, and identifying it early and intervening promptly can reduce the necessity for extensive medical treatments and lengthy diagnostic procedures for those impacted by ASD. This research is designed with two types of experimentation for ASD analysis. In the first set of experiments, authors utilized three feature engineering techniques (Chi-square, backward feature elimination, and PCA) with multiple machine learning models for autism presence prediction in toddlers. The proposed XGBoost 2.0 obtained 99% accuracy, F1 score, and recall with 98% precision with chi-square significant features. In the second scenario, main focus shifts to identifying tailored educational methods for children with ASD through the assessment of their behavioral, verbal, and physical responses. Again, the proposed approach performs well with 99% accuracy, F1 score, recall, and precision. In this research, cross-validation technique is also implemented to check the stability of the proposed model along with the comparison of previously published research works to show the significance of the proposed model. This study aims to develop personalized educational strategies for individuals with ASD using machine learning techniques to meet their specific needs better.

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基于选择性特征和可解释人工智能的以数据为中心的自闭症谱系障碍自动预测方法。
自闭症谱系障碍(ASD)是一种神经发育疾病,其特征是在认知功能、理解语言、识别物体、与他人互动和有效沟通方面存在明显的障碍。其病因主要是遗传,及早发现并及时干预可以减少受 ASD 影响的人接受大量医疗和冗长诊断程序的必要性。这项研究设计了两种类型的实验来分析 ASD。在第一组实验中,作者利用三种特征工程技术(Chi-square、后向特征消除和 PCA)和多种机器学习模型来预测幼儿是否患有自闭症。所提出的 XGBoost 2.0 获得了 99% 的准确率、F1 分数和 98% 的召回率,其中 Chi-square 特征显著。在第二种情况下,主要重点转移到通过评估 ASD 儿童的行为、语言和身体反应来确定适合他们的教育方法。同样,所提出的方法表现出色,准确率、F1 分数、召回率和精确度均达到 99%。在这项研究中,还采用了交叉验证技术来检查所提模型的稳定性,并与以前发表的研究成果进行比较,以显示所提模型的重要性。本研究旨在利用机器学习技术为 ASD 患者制定个性化教育策略,以更好地满足他们的特定需求。
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来源期刊
Frontiers in Computational Neuroscience
Frontiers in Computational Neuroscience MATHEMATICAL & COMPUTATIONAL BIOLOGY-NEUROSCIENCES
CiteScore
5.30
自引率
3.10%
发文量
166
审稿时长
6-12 weeks
期刊介绍: Frontiers in Computational Neuroscience is a first-tier electronic journal devoted to promoting theoretical modeling of brain function and fostering interdisciplinary interactions between theoretical and experimental neuroscience. Progress in understanding the amazing capabilities of the brain is still limited, and we believe that it will only come with deep theoretical thinking and mutually stimulating cooperation between different disciplines and approaches. We therefore invite original contributions on a wide range of topics that present the fruits of such cooperation, or provide stimuli for future alliances. We aim to provide an interactive forum for cutting-edge theoretical studies of the nervous system, and for promulgating the best theoretical research to the broader neuroscience community. Models of all styles and at all levels are welcome, from biophysically motivated realistic simulations of neurons and synapses to high-level abstract models of inference and decision making. While the journal is primarily focused on theoretically based and driven research, we welcome experimental studies that validate and test theoretical conclusions. Also: comp neuro
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