Environmental microplastic and phthalate esters co-contamination, interrelationships, co-toxicity and mechanisms. A review.

Abstract

Plastics have been pervasive in society for decades, causing extensive environmental contamination. The co-occurrence of microplastics (MPs) and phthalate esters (PAEs) in the environment has significant implications for the global population. This review focuses on the simultaneous presence of MPs and PAEs, exploring co-pollution, leaching, adsorption, correlation, and co-toxicity. Both MPs and PAEs are found in various environmental compartments, including water, sediments, aquatic organisms, pig feed, masks, gloves, and liquid waste from garbage infiltration. Factors such as time, temperature, UV light exposure, and the type of MPs can influence the leaching and adsorption of PAEs onto MPs. The correlation between MPs and PAEs allows for the use of PAEs as indicators for the presence of MPs. However, current constraints, like limited data availability and regional coverage, impede the feasibility of comprehensive tracking. Additionally, the combined effects of MPs and PAEs demonstrate synergistic toxicity, leading to adverse health effects such as reproductive toxicity, neurotoxicity, hepatotoxicity, nephrotoxicity, and other toxicities, primarily mediated by oxidative stress processes. Consequently, the findings provide valuable insights for future researchers and regulatory bodies, enabling the development of more effective strategies to address the simultaneous presence of microplastics and PAEs and mitigate their harmful impacts on human health.