Metabolic bone disease in an extinct neotropical primate

IF 1.3 3区地球科学 Q3 PALEONTOLOGY International Journal of Paleopathology Pub Date : 2024-11-19 DOI:10.1016/j.ijpp.2024.11.003

André Vieira Araújo , Mário André Trindade Dantas , Alexandre Liparini , Mario Alberto Cozzuol , Lauren B. Halenar-Price , Rodrigo Martins Ribeiro , Fernando Henrique de Souza Barbosa , Francisco Bandeira , Hermínio Ismael de Araújo Júnior

{"title":"Metabolic bone disease in an extinct neotropical primate","authors":"André Vieira Araújo , Mário André Trindade Dantas , Alexandre Liparini , Mario Alberto Cozzuol , Lauren B. Halenar-Price , Rodrigo Martins Ribeiro , Fernando Henrique de Souza Barbosa , Francisco Bandeira , Hermínio Ismael de Araújo Júnior","doi":"10.1016/j.ijpp.2024.11.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>This work evaluates the potential presence of bone disease in an extinct primate from late Pleistocene of Brazil.</div></div><div><h3>Materials</h3><div>The skull and post crania of an extinct platyrrhine primate, curated by the Museu de Ciências Naturais PUC, Brazil.</div></div><div><h3>Methods</h3><div>Pathological changes were noted via analysis of radiographic images and CT of the affected bones.</div></div><div><h3>Results</h3><div>The lesions noted include cortical thickening, sclerosis, and coarse trabeculae in the skull and long bones.</div></div><div><h3>Conclusions</h3><div>The features observed support the diagnosis of metabolic bone disease with lesions comparable to those seen in Paget's disease.</div></div><div><h3>Significance</h3><div>This specimen appears to be the only case is of metabolic bone disease in an extinct New World monkey and adds data to the paleopathological record of South American primates.</div></div><div><h3>Limitations</h3><div>The absence of other skeletal materials from individuals of the same genus for comparison makes differential diagnosis challenging, and conclusions must be drawn with caution.</div></div><div><h3>Suggestions for further research</h3><div>A more complete comparative sample of images involving more genera of living and extinct platyrrhines can help to rule out morphological oddities and design a more accurate diagnosis.</div></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"48 ","pages":"Pages 1-12"},"PeriodicalIF":1.3000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Paleopathology","FirstCategoryId":"89","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1879981724003152","RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PALEONTOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

This work evaluates the potential presence of bone disease in an extinct primate from late Pleistocene of Brazil.

Materials

The skull and post crania of an extinct platyrrhine primate, curated by the Museu de Ciências Naturais PUC, Brazil.

Methods

Pathological changes were noted via analysis of radiographic images and CT of the affected bones.

Results

The lesions noted include cortical thickening, sclerosis, and coarse trabeculae in the skull and long bones.

Conclusions

The features observed support the diagnosis of metabolic bone disease with lesions comparable to those seen in Paget's disease.

Significance

This specimen appears to be the only case is of metabolic bone disease in an extinct New World monkey and adds data to the paleopathological record of South American primates.

Limitations

The absence of other skeletal materials from individuals of the same genus for comparison makes differential diagnosis challenging, and conclusions must be drawn with caution.

Suggestions for further research

A more complete comparative sample of images involving more genera of living and extinct platyrrhines can help to rule out morphological oddities and design a more accurate diagnosis.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

一种已灭绝的新热带灵长类动物的代谢性骨病。

目的：本研究评估了巴西晚更新世的一种已灭绝灵长类动物可能存在的骨病：这项研究评估了巴西晚更新世一种已灭绝灵长类动物可能存在的骨病：材料：巴西 PUC 自然科学博物馆收藏的一种已灭绝的板齿灵长类动物的头骨和后颅骨：方法：通过分析受影响骨骼的放射影像和 CT，发现病理变化：结果：发现的病变包括头骨和长骨的皮质增厚、硬化和粗小梁：结论：观察到的特征支持代谢性骨病的诊断，其病变与帕吉特氏病的病变相似：该标本似乎是已灭绝的新大陆猴类中唯一的代谢性骨病病例，为南美洲灵长类动物的古病理学记录增添了数据：局限性：由于缺乏同属个体的其他骨骼材料进行比较，因此鉴别诊断具有挑战性，必须谨慎得出结论：进一步研究的建议：更完整的图像比较样本涉及更多在世和已灭绝的板手类属，有助于排除形态学上的怪异之处，并设计出更准确的诊断方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

International Journal of Paleopathology PALEONTOLOGY-PATHOLOGY

CiteScore

2.90

自引率

25.00%

发文量

期刊介绍： Paleopathology is the study and application of methods and techniques for investigating diseases and related conditions from skeletal and soft tissue remains. The International Journal of Paleopathology (IJPP) will publish original and significant articles on human and animal (including hominids) disease, based upon the study of physical remains, including osseous, dental, and preserved soft tissues at a range of methodological levels, from direct observation to molecular, chemical, histological and radiographic analysis. Discussion of ways in which these methods can be applied to the reconstruction of health, disease and life histories in the past is central to the discipline, so the journal would also encourage papers covering interpretive and theoretical issues, and those that place the study of disease at the centre of a bioarchaeological or biocultural approach. Papers dealing with historical evidence relating to disease in the past (rather than history of medicine) will also be published. The journal will also accept significant studies that applied previously developed techniques to new materials, setting the research in the context of current debates on past human and animal health.