Submillimeter fiber robots capable of decoupled macro-micro motion for endoluminal manipulation

IF 11.7 1区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES Science Advances Pub Date : 2024-11-22 DOI:10.1126/sciadv.adr6428
Cheng Zhou, Zheng Xu, Zecai Lin, Xiaotong Qin, Jingyuan Xia, Xiaojie Ai, Chuqian Lou, Ziyi Huang, Shaoping Huang, Huanghua Liu, Yun Zou, Weidong Chen, Guang-Zhong Yang, Anzhu Gao
{"title":"Submillimeter fiber robots capable of decoupled macro-micro motion for endoluminal manipulation","authors":"Cheng Zhou,&nbsp;Zheng Xu,&nbsp;Zecai Lin,&nbsp;Xiaotong Qin,&nbsp;Jingyuan Xia,&nbsp;Xiaojie Ai,&nbsp;Chuqian Lou,&nbsp;Ziyi Huang,&nbsp;Shaoping Huang,&nbsp;Huanghua Liu,&nbsp;Yun Zou,&nbsp;Weidong Chen,&nbsp;Guang-Zhong Yang,&nbsp;Anzhu Gao","doi":"10.1126/sciadv.adr6428","DOIUrl":null,"url":null,"abstract":"<div >Endoluminal and endocavitary intervention via natural orifices of the body is an emerging trend in medicine, further underpinning the future of early intervention and precision surgery. This motivates the development of small continuum robots to navigate freely in confined and tortuous environment. The trade-off between a large range of motion and high precision with concomitant actuation cross-talk poses a major challenge. Here, we present a submillimeter-scale fiber robot (~1 mm) capable of decoupled macro and micro manipulations for intervention and operation. The thin optical fibers, working both as mechanical tendons and light waveguides, can be pulled/pushed to actuate the macro tendon-driven continuum robot and transmit light to actuate the liquid crystal elastomer–based micro built-in light-driven parallel robot. The combination of the decoupled macro and micro motions can accomplish accurate cross-scale motion from several millimeters down to tens of micrometers. In vivo animal studies are performed to demonstrate its positioning accuracy of precise micro operations in endoluminal or endocavitary intervention.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"10 47","pages":""},"PeriodicalIF":11.7000,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584019/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science Advances","FirstCategoryId":"103","ListUrlMain":"https://www.science.org/doi/10.1126/sciadv.adr6428","RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Endoluminal and endocavitary intervention via natural orifices of the body is an emerging trend in medicine, further underpinning the future of early intervention and precision surgery. This motivates the development of small continuum robots to navigate freely in confined and tortuous environment. The trade-off between a large range of motion and high precision with concomitant actuation cross-talk poses a major challenge. Here, we present a submillimeter-scale fiber robot (~1 mm) capable of decoupled macro and micro manipulations for intervention and operation. The thin optical fibers, working both as mechanical tendons and light waveguides, can be pulled/pushed to actuate the macro tendon-driven continuum robot and transmit light to actuate the liquid crystal elastomer–based micro built-in light-driven parallel robot. The combination of the decoupled macro and micro motions can accomplish accurate cross-scale motion from several millimeters down to tens of micrometers. In vivo animal studies are performed to demonstrate its positioning accuracy of precise micro operations in endoluminal or endocavitary intervention.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
亚毫米级光纤机器人,可进行宏观与微观解耦运动,用于腔内操作。
通过人体自然孔道进行腔内和腔内介入治疗是医学界的一个新兴趋势,为未来的早期介入治疗和精准外科手术奠定了基础。这推动了小型连续机器人的发展,使其能够在狭窄迂回的环境中自由导航。大运动范围和高精度之间的权衡以及随之而来的执行交叉干扰是一项重大挑战。在这里,我们展示了一种亚毫米级光纤机器人(约 1 毫米),它能够进行解耦的宏观和微观操作,以进行干预和操作。纤细的光纤既是机械肌腱,又是光波导,可以通过拉/推来驱动宏观肌腱驱动的连续机器人,也可以通过光传输来驱动基于液晶弹性体的微型内置光驱动并联机器人。宏观和微观运动的解耦组合可以实现从几毫米到几十微米的精确跨尺度运动。体内动物实验证明了它在腔内或腔内介入手术中精确微操作的定位精度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Science Advances
Science Advances 综合性期刊-综合性期刊
CiteScore
21.40
自引率
1.50%
发文量
1937
审稿时长
29 weeks
期刊介绍: Science Advances, an open-access journal by AAAS, publishes impactful research in diverse scientific areas. It aims for fair, fast, and expert peer review, providing freely accessible research to readers. Led by distinguished scientists, the journal supports AAAS's mission by extending Science magazine's capacity to identify and promote significant advances. Evolving digital publishing technologies play a crucial role in advancing AAAS's global mission for science communication and benefitting humankind.
期刊最新文献
Enhanced dual-mode imaging: Superior photoacoustic and ultrasound endoscopy in live pigs using a transparent ultrasound transducer Acoustic virtual 3D scaffold for direct-interacting tumor organoid–immune cell coculture systems Bridging activity gaps between batch and flow reactor configurations in the electroreduction of carbon dioxide CalDAG-GEFI acts as a guanine nucleotide exchange factor for LRRK2 to regulate LRRK2 function and neurodegeneration Catalytic kinetic resolution of helical polycyclic phenols via an organocatalyzed enantioselective dearomative amination reaction
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1