Trajectories of cognitive function and frailty in older adults in China: a longitudinal study.

IF 4.5 2区 医学 Q2 GERIATRICS & GERONTOLOGY Frontiers in Aging Neuroscience Pub Date : 2024-11-14 eCollection Date: 2024-01-01 DOI:10.3389/fnagi.2024.1465914
Xiaoyi Ji, Yue Wu, Zijie Gu, Zhujun Zhong, Kerui Wang, Suni Ye, Yang Wan, Peiyuan Qiu
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Abstract

Background: Cognitive impairment and frailty are common issues in older adults. Understanding the co-development trajectories of these conditions can provide valuable sights for early detection and intervention in high-risk individuals.

Objectives: This study aims to identify the co-development of cognitive function and frailty and explore the associated characteristics.

Methods: We analyzed data from 8,418 individuals aged 55 years and above who participated in the China Health and Retirement Longitudinal Survey between 2011 and 2018. Group-based dual trajectory modeling and logistic regression were used to identify trajectory groups and assess associations with risk factors.

Results: Two distinct dual trajectories were identified: "Consistently Robust" group (76.12%) and "Consistently Severe" group (23.88%). Factors such as being female, older age, lower levels of education, residing in rural areas, being unmarried, and having comorbidities such as hypertension, diabetes, complete tooth loss, vision impairment, or hearing impairment were associated with a higher likelihood of being assigned to the "Consistently Severe" group.

Conclusion: Our findings suggest a co-development pattern between cognitive function and frailty in Chinese older adults aged 55 years and above. While cognitive impairment may be irreversible, frailty is a condition that can be potentially reversed. Early detecting is crucial in preventing cognitive decline, considering the shared trajectory of these conditions.

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中国老年人认知功能和衰弱的发展轨迹:一项纵向研究。
背景:认知障碍和虚弱是老年人的常见问题。了解这些疾病的共同发展轨迹可以为高危人群的早期发现和干预提供有价值的视角。目的:本研究旨在确定认知功能与虚弱的共同发展,并探讨其相关特征。方法:我们分析了2011年至2018年参加中国健康与退休纵向调查的8418名55岁及以上个体的数据。使用基于组的双轨迹模型和逻辑回归来确定轨迹组并评估与危险因素的关联。结果:发现两种明显的双轨迹:“持续稳健”组(76.12%)和“持续严重”组(23.88%)。女性、年龄较大、受教育程度较低、居住在农村地区、未婚以及患有高血压、糖尿病、全牙脱落、视力障碍或听力障碍等合并症等因素与被分配到“持续严重”组的可能性较高相关。结论:我们的研究结果表明,在中国55岁及以上的老年人中,认知功能和虚弱之间存在共同发展模式。虽然认知障碍可能是不可逆转的,但虚弱是一种可能被逆转的状况。考虑到这些疾病的共同轨迹,早期发现对于预防认知能力下降至关重要。
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来源期刊
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience GERIATRICS & GERONTOLOGY-NEUROSCIENCES
CiteScore
6.30
自引率
8.30%
发文量
1426
期刊介绍: Frontiers in Aging Neuroscience is a leading journal in its field, publishing rigorously peer-reviewed research that advances our understanding of the mechanisms of Central Nervous System aging and age-related neural diseases. Specialty Chief Editor Thomas Wisniewski at the New York University School of Medicine is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
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