An efficient deep unrolling network for sparse-view CT reconstruction via alternating optimization of dense-view sinograms and images.

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL Physics in medicine and biology Pub Date : 2025-01-15 DOI:10.1088/1361-6560/ad9dac
Chang Sun, Yitong Liu, Hongwen Yang
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Abstract

Objective. Recently, there have been many advancements in deep unrolling methods for sparse-view computed tomography (SVCT) reconstruction. These methods combine model-based and deep learning-based reconstruction techniques, improving the interpretability and achieving significant results. However, they are often computationally expensive, particularly for clinical raw projection data with large sizes. This study aims to address this issue while maintaining the quality of the reconstructed image.Approach. The SVCT reconstruction task is decomposed into two subproblems using the proximal gradient method: optimizing dense-view sinograms and optimizing images. Then dense-view sinogram inpainting, image-residual learning, and image-refinement modules are performed at each iteration stage using deep neural networks. Unlike previous unrolling methods, the proposed method focuses on optimizing dense-view sinograms instead of full-view sinograms. This approach not only reduces computational resources and runtime but also minimizes the challenge for the network to perform sinogram inpainting when the sparse ratio is extremely small, thereby decreasing the propagation of estimation error from the sinogram domain to the image domain.Main results. The proposed method successfully reconstructs an image (512 × 512 pixels) from real-size (2304 × 736) projection data, with 3.39 M training parameters and an inference time of 0.09 s per slice on a GPU. The proposed method also achieves superior quantitative and qualitative results compared with state-of-the-art deep unrolling methods on datasets with sparse ratios of 1/12 and 1/18, especially in suppressing artifacts and preserving structural details. Additionally, results show that using dense-view sinogram inpainting not only accelerates the computational speed but also leads to faster network convergence and further improvements in reconstruction results.Significance. This research presents an efficient dual-domain deep unrolling technique that produces excellent results in SVCT reconstruction while requiring small computational resources. These findings have important implications for speeding up deep unrolling CT reconstruction methods and making them more practical for processing clinical CT projection data.

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一种基于密集图和图像交替优化的稀疏视图CT重构深度展开网络。
目的:稀疏视图计算机断层扫描(SVCT)重建的深度展开方法取得了许多进展。这些方法结合了基于模型和基于深度学习的重建技术,提高了可解释性,取得了显著的结果。然而,它们通常在计算上很昂贵,特别是对于大尺寸的临床原始投影数据。本研究旨在解决这一问题,同时保持重建图像的质量。方法:采用近端梯度法将SVCT重构任务分解为两个子问题:优化密集图和优化图像。然后在每个迭代阶段使用深度神经网络执行密集视图sinogram inpainting、图像残差学习和图像细化模块。与以往的展开方法不同,本文提出的方法侧重于优化密集视图图,而不是全视图图。该方法不仅减少了计算资源和运行时间,而且最大限度地减少了网络在稀疏比极小的情况下进行正弦图绘制的挑战,从而减少了估计误差从正弦图域到图像域的传播。主要结果:该方法成功地从真实尺寸(2304×736)的投影数据中重建图像(512×512像素),在GPU上训练参数为3.39 M,每片推理时间为0.09秒。在稀疏比为1/12和1/18的数据集上,与目前最先进的深度展开方法相比,该方法在抑制伪影和保留结构细节方面取得了更好的定量和定性结果。此外,研究结果表明,在绘制中使用密集视图正弦图不仅可以加快计算速度,而且可以加快网络收敛速度,进一步改善重建结果。意义:本研究提出了一种高效的双域深度展开技术,该技术在需要较少计算资源的情况下,在SVCT重建中取得了很好的效果。这些发现对于加快深度展开CT重建方法的速度,使其在处理临床CT投影数据方面更加实用具有重要意义。
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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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