A multiplexing method based on multidimensional readout method.

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL Physics in medicine and biology Pub Date : 2025-02-10 DOI:10.1088/1361-6560/adae4c
Xin Yu, Han Liu, Huiping Zhao, Jinyong Tao, Da Liang, Jiayang Zeng, Jianfeng Xu, Siwei Xie, Qiyu Peng
{"title":"A multiplexing method based on multidimensional readout method<sup />.","authors":"Xin Yu, Han Liu, Huiping Zhao, Jinyong Tao, Da Liang, Jiayang Zeng, Jianfeng Xu, Siwei Xie, Qiyu Peng","doi":"10.1088/1361-6560/adae4c","DOIUrl":null,"url":null,"abstract":"<p><p><i>Objective.</i>To develop and validate a novel multidimensional readout method that significantly reduces the number of readout channels (NRC) in PET detectors while maintaining high spatial and energy performance.<i>Approach.</i>We arranged a3×3×4SiPM array in multiple dimensions and employed row/column/layer summation with a resistor-based splitting circuit. We then applied denoising methods to enhance the peak-to-valley ratio in the decoding map, ensuring accurate crystal-position determination. Additionally, we investigated the system's energy response at 511 keV and evaluated the suitability for both clinical and research PET systems.<i>Main results.</i>The proposed multidimensional readout method achieved a favorable multiplexing ratio, lowering the total NRCs without compromising energy resolution at 511 keV. Our tests demonstrated that a SiPM bias voltage of 31 V effectively balances gain and saturation effects, resulting in reliable energy measurements.<i>Significance.</i>By reducing system complexity, cost, and power consumption, the multidimensional readout method presents a practical alternative to conventional readout schemes for PET and other large-scale sensor arrays. Additionally, the approach can manage simultaneous multi-layer hits by arranging detector layers and, when needed, uses ICS detection to correct for scatter events. Its adaptable architecture allows scaling to higher dimensions for broader applications (e.g. SPECT, CT, LiDAR). These features make it a valuable contribution toward more efficient, high-performance imaging technologies in both clinical and industrial settings.</p>","PeriodicalId":20185,"journal":{"name":"Physics in medicine and biology","volume":" ","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics in medicine and biology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1088/1361-6560/adae4c","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0

Abstract

Objective.To develop and validate a novel multidimensional readout method that significantly reduces the number of readout channels (NRC) in PET detectors while maintaining high spatial and energy performance.Approach.We arranged a3×3×4SiPM array in multiple dimensions and employed row/column/layer summation with a resistor-based splitting circuit. We then applied denoising methods to enhance the peak-to-valley ratio in the decoding map, ensuring accurate crystal-position determination. Additionally, we investigated the system's energy response at 511 keV and evaluated the suitability for both clinical and research PET systems.Main results.The proposed multidimensional readout method achieved a favorable multiplexing ratio, lowering the total NRCs without compromising energy resolution at 511 keV. Our tests demonstrated that a SiPM bias voltage of 31 V effectively balances gain and saturation effects, resulting in reliable energy measurements.Significance.By reducing system complexity, cost, and power consumption, the multidimensional readout method presents a practical alternative to conventional readout schemes for PET and other large-scale sensor arrays. Additionally, the approach can manage simultaneous multi-layer hits by arranging detector layers and, when needed, uses ICS detection to correct for scatter events. Its adaptable architecture allows scaling to higher dimensions for broader applications (e.g. SPECT, CT, LiDAR). These features make it a valuable contribution toward more efficient, high-performance imaging technologies in both clinical and industrial settings.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
求助全文
约1分钟内获得全文 去求助
来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
期刊最新文献
Initial results of the Hyperion IIDPET insert for simultaneous PET-MRI applied to atherosclerotic plaque imaging in New-Zealand white rabbits. A multiplexing method based on multidimensional readout method. Diffusion transformer model with compact prior for low-dose PET reconstruction. A dual-domain network with division residual connection and feature fusion for CBCT scatter correction. A ConvLSTM-based model for predicting thermal damage during laser interstitial thermal therapy.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1