{"title":"Visible- and Near-Infrared Light-Driven Molecular Photoswitches for Biological Applications","authors":"Yang Xu, Yuqi Tang, Quan Li","doi":"10.1002/adfm.202416359","DOIUrl":null,"url":null,"abstract":"<p>Molecular photoswitches can undergo isomerization under light exposure, making them uniquely attractive for high spatiotemporal resolution remote control of biological functions. Visible and near-infrared (NIR) light, with their low energy consumption, high safety, and strong tissue penetration, are particularly suitable for biological applications. Therefore, developing visible- and NIR light-driven molecular photoswitches for biological use is of great significance. This review introduces the most common visible- and NIR light-driven molecular photoswitches and presents the state-of-art of their applications in bioimaging, biosensing, drug delivery, photocontrolled cancer phototherapy, and photopharmacology. The opportunities and challenges of the photoswitches for their future development in biological applications are outlined.</p>","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"35 22","pages":""},"PeriodicalIF":19.0000,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Functional Materials","FirstCategoryId":"88","ListUrlMain":"https://advanced.onlinelibrary.wiley.com/doi/10.1002/adfm.202416359","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Molecular photoswitches can undergo isomerization under light exposure, making them uniquely attractive for high spatiotemporal resolution remote control of biological functions. Visible and near-infrared (NIR) light, with their low energy consumption, high safety, and strong tissue penetration, are particularly suitable for biological applications. Therefore, developing visible- and NIR light-driven molecular photoswitches for biological use is of great significance. This review introduces the most common visible- and NIR light-driven molecular photoswitches and presents the state-of-art of their applications in bioimaging, biosensing, drug delivery, photocontrolled cancer phototherapy, and photopharmacology. The opportunities and challenges of the photoswitches for their future development in biological applications are outlined.
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