Minimally Invasive Total Versus Supracervical Hysterectomy With Sacrocolpopexy.

IF 0.8 Q4 OBSTETRICS & GYNECOLOGY Urogynecology (Hagerstown, Md.) Pub Date : 2024-10-01 Epub Date: 2024-05-18 DOI:10.1097/SPV.0000000000001530
Lauren E Giugale, Kristine M Ruppert, Sruthi L Muluk, Stephanie M Glass Clark, Megan S Bradley, Jennifer M Wu, Catherine A Matthews
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Abstract

Importance: Limited data exist comparing total laparoscopic hysterectomy (TLH) versus laparoscopic supracervical hysterectomy (LSCH) at the time of minimally invasive sacrocolpopexy for uterovaginal prolapse.

Objectives: The objective of this study was to compare TLH versus LSCH at the time of minimally invasive sacrocolpopexy for uterovaginal prolapse, hypothesizing that LSCH would demonstrate a higher proportion of recurrent prolapse, but a lower proportion of mesh exposures.

Study design: This was a retrospective, secondary analysis comparing a prospective cohort of patients undergoing TLH sacrocolpopexy versus a retrospective cohort of patients who had undergone LSCH sacrocolpopexy. Our primary outcome was composite anatomic pelvic organ prolapse recurrence (prolapse beyond hymen, apical descent > half vaginal length, retreatment). Secondary outcomes included vaginal mesh exposures.

Results: There were 733 procedures: 184 (25.1%) TLH sacrocolpopexy and 549 (74.9%) LSCH sacrocolpopexy. Median follow-up was longer in the TLH cohort (369 [IQR 354-386] vs 190 [IQR 63-362] days, P < 0.01). There was no difference in composite prolapse recurrence between groups on bivariable analysis (3.3% vs 4.7%, P = 0.40). However, multivariable logistic regression demonstrated that TLH sacrocolpopexy had lower odds of composite pelvic organ prolapse recurrence than LSCH sacrocolpopexy (OR 0.21, 95% CI 0.05-0.82, P = 0.02). Among procedures with lightweight mesh types, TLH demonstrated a higher proportion of mesh exposures compared to LSCH (10 [5.4%] vs 4 [1.1%], P < 0.01); however, this was not significant after controlling for confounders (OR 4.51, 95% CI 0.88-39.25, P = 0.08). There were no differences in retreatment or reoperation.

Conclusion: For the treatment of uterovaginal prolapse, both TLH and LSCH are acceptable methods of concomitant hysterectomy at the time of minimally invasive sacrocolpopexy, albeit with likely different risk profiles.

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微创全子宫切除术与宫颈上子宫切除术联合骶髋固定术的比较。
重要性:腹腔镜全子宫切除术(TLH)与腹腔镜宫颈上子宫切除术(LSCH)在微创骶阴道固定术治疗子宫阴道脱垂时的比较资料有限。目的:本研究的目的是比较微创骶阴道固定术治疗子宫阴道脱垂时TLH与LSCH的差异,假设LSCH的复发脱垂比例较高,但补片暴露比例较低。研究设计:这是一项回顾性的二级分析,比较了TLH骶髋固定术患者的前瞻性队列与LSCH骶髋固定术患者的回顾性队列。我们的主要结果是复合性解剖盆腔器官脱垂复发(脱垂超过处女膜,根尖下降超过阴道长度的一半,再治疗)。次要结果包括阴道网片暴露。结果:共有733例手术,其中TLH骶髋固定术184例(25.1%),LSCH骶髋固定术549例(74.9%)。TLH组的中位随访时间更长(369 [IQR 354-386]天和190 [IQR 63-362]天,P < 0.01)。双变量分析两组间复合脱垂复发率无差异(3.3% vs 4.7%, P = 0.40)。然而,多变量logistic回归分析显示,TLH骶colpopexy复合盆腔器官脱垂复发的几率低于LSCH骶colpopexy (OR 0.21, 95% CI 0.05 ~ 0.82, P = 0.02)。在使用轻型网片类型的手术中,TLH比LSCH显示出更高的网片暴露比例(10[5.4%]比4 [1.1%],P < 0.01);然而,在控制混杂因素后,这并不显著(OR 4.51, 95% CI 0.88-39.25, P = 0.08)。两组再治疗和再手术无明显差异。结论:对于子宫阴道脱垂的治疗,TLH和LSCH都是微创骶阴道固定术同时进行子宫切除术的可接受方法,尽管它们的风险可能不同。
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