Harnessing the dynamics of plant organic acids metabolism following abiotic stresses.

Abstract

Plants encounter various environmental stresses throughout development, including shade, high light, drought, hypoxia, extreme temperatures, and metal toxicity, all of which adversely affect growth and productivity. Organic acids (OAs), besides serving as intermediates in the tricarboxylic acid (TCA) cycle, play crucial roles in multiple metabolic pathways and cellular compartments, including mitochondrial metabolism, amino acid metabolism, the glyoxylate cycle, and the photosynthetic mechanisms of C4 and CAM plants. OAs contribute to stress tolerance by acting as root chelating agents, regulating ATP production, and providing reducing power for detoxifying reactive oxygen species (ROS). They also participate in the biosynthesis of solutes involved in stress signaling and osmoregulation, particularly during stomatal movements. This review explores how OAs regulate plant metabolism in response to specific abiotic stresses, emphasizing the increased production of malate, citrate, and succinate, which enhance resilience to water deficits, metal toxicity, and flooding. Since these mechanisms involve intricate metabolic networks, changes in OA metabolism present promising and underexplored potential for agriculture. Understanding these mechanisms could lead to innovative strategies for developing crops with greater resilience to climate change, whether through genetic manipulation or by selecting varieties with favorable metabolic responses to stress.