[Research progress on prognostic prediction models for patients undergoing extracorporeal membrane oxygenation].

Hanming Gao, Junyu Lu
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Abstract

Extracorporeal membrane oxygenation (ECMO), as a critical life support technology, has played a significant role in treating patients with refractory respiratory and circulatory failure. In recent years, with the advancements in medical technology, the scope of application of ECMO has been expanding, especially in the fields of acute respiratory distress syndrome, cardiogenic shock and other important roles. However, its high costs, complex operation, and associated risks of complications remain challenges in clinical practice. At present, an increasing number of studies have focused on developing and validating ECMO prognostic models. Developing precise prognostic prediction models is crucial for optimizing treatment decisions and improving patient survival rates. This article categorizes existing prognostic models for adult ECMO patients based on methodological classification, patient population, and theoretical framework. It highlights the limitations of current models in terms of sample size, multi-center validation, static data analysis, and model applicability. Moreover, it proposes future directions for model development, such as multi-center prospective studies, integration of machine learning and deep learning technologies, and increased focus on long-term outcomes, offering insights for researchers to improve model construction and explore new research directions.

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体外膜氧合患者预后预测模型的研究进展
体外膜氧合(Extracorporeal membrane oxygenation, ECMO)作为一项重要的生命支持技术,在治疗难治性呼吸和循环衰竭患者中发挥着重要作用。近年来,随着医疗技术的进步,ECMO的应用范围不断扩大,特别是在急性呼吸窘迫综合征、心源性休克等领域发挥了重要作用。然而,其成本高、操作复杂、并发症风险大,仍是临床实践中的挑战。目前,越来越多的研究集中于开发和验证ECMO预后模型。开发精确的预后预测模型对于优化治疗决策和提高患者存活率至关重要。本文根据方法分类、患者群体和理论框架对成人ECMO患者的现有预后模型进行了分类。它突出了当前模型在样本量、多中心验证、静态数据分析和模型适用性方面的局限性。提出了未来模型发展的方向,如多中心前瞻性研究、机器学习与深度学习技术的融合、对长期结果的关注等,为研究人员改进模型构建、探索新的研究方向提供了思路。
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来源期刊
Zhonghua wei zhong bing ji jiu yi xue
Zhonghua wei zhong bing ji jiu yi xue Medicine-Critical Care and Intensive Care Medicine
CiteScore
1.00
自引率
0.00%
发文量
42
期刊最新文献
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