The ability of end-tidal carbon dioxide value to predict the risk of major cardiovascular events in patients with acute coronary syndrome.

IF 1.1 4区医学 Q2 MEDICINE, GENERAL & INTERNAL Acta Clinica Belgica Pub Date : 2025-01-21 DOI:10.1080/17843286.2025.2456696

Nazım Onur Can, Senol Arslan, Erdal Tekin, Halil İbrahim Doru

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Abstract

Objectives: In this study, the capacity of End-tidal carbon dioxide (EtCO2) levels to predict the risk of major cardiovascular events (MACE) in patients diagnosed with acute coronary syndrome and the relationship between risk scoring systems (TIMI, GRACE, HEART) and EtCO2 values were examined.

Methods: EtCO2 values of the patients in the study were measured with a capnography device. Each patient's MACE status was recorded.

Results: The results we found in our study are as follows: (i) EtCO2 values were significantly lower in the group with MACE (n = 45) than in the group without MACE (n = 288) (p < 0.05). (ii) According to ROC analysis, EtCO2 was effective in predicting one-month mortality (AUC = 0.81, p < 0.00). (iii) The optimal EtCO2 cut-off point was 30 mmHg. This threshold value provided both sensitivity and specificity for the risk of MACE. (IV) Significant associations were found between EtCO2 and GRACE, TIMI and HEART scoring systems. EtCO2 values were significantly higher in the low-risk groups. (V) EtCO2 was significantly different in all three risk scoring systems in the non-MACE group, but only with the GRACE score in the MACE group.

Conclusion: This study demonstrated that EtCO2 is a valuable indicator for predicting the risk of MACE in patients with ACS.

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潮末二氧化碳值预测急性冠脉综合征患者主要心血管事件发生风险的能力

目的：本研究探讨急性冠脉综合征患者潮末二氧化碳（EtCO2）水平预测主要心血管事件（MACE）风险的能力，以及风险评分系统（TIMI、GRACE、HEART）与EtCO2值之间的关系。方法：采用血管造影仪测定患者的EtCO2值。记录每位患者的MACE状态。结果：我们的研究结果如下：(i) MACE组（n = 45）的EtCO2值明显低于未MACE组（n = 288）（p p）结论：本研究表明EtCO2值是预测ACS患者MACE发生风险的有价值的指标。

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来源期刊

Acta Clinica Belgica MEDICINE, GENERAL & INTERNAL-

CiteScore

3.50

自引率

0.00%

发文量

期刊介绍： Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine primarily publishes papers on clinical medicine, clinical chemistry, pathology and molecular biology, provided they describe results which contribute to our understanding of clinical problems or describe new methods applicable to clinical investigation. Readership includes physicians, pathologists, pharmacists and physicians working in non-academic and academic hospitals, practicing internal medicine and its subspecialties.