Christina Pacholec, Bente Flatland, Hehuang Xie, Kurt Zimmerman
{"title":"Harnessing artificial intelligence for enhanced veterinary diagnostics: A look to quality assurance, Part II External validation.","authors":"Christina Pacholec, Bente Flatland, Hehuang Xie, Kurt Zimmerman","doi":"10.1111/vcp.13407","DOIUrl":null,"url":null,"abstract":"<p><p>Artificial intelligence (AI) is emerging as a valuable diagnostic tool in veterinary medicine, offering affordable and accessible tests that can match or even exceed the performance of medical professionals in similar tasks. Despite the promising outcomes of using AI systems (AIS) as highly accurate diagnostic tools, the field of quality assurance in AIS is still in its early stages. Our Part I manuscript focused on the development and technical validation of an AIS. In Part II, we explore the next step in development: external validation (i.e., in silico testing). This phase is a critical quality assurance component for any AIS intended for medical use, ensuring that high-quality diagnostics remain the standard in veterinary medicine. The quality assurance process for evaluating an AIS involves rigorous: (1) investigation of sources of bias, (2) application of calibration methods and prediction of uncertainty, (3) implementation of safety monitoring systems, and (4) assessment of repeatability and robustness. Testing with unseen data is an essential part of in silico testing, as it ensures the accuracy and precision of the AIS output.</p>","PeriodicalId":23593,"journal":{"name":"Veterinary clinical pathology","volume":" ","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary clinical pathology","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1111/vcp.13407","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Artificial intelligence (AI) is emerging as a valuable diagnostic tool in veterinary medicine, offering affordable and accessible tests that can match or even exceed the performance of medical professionals in similar tasks. Despite the promising outcomes of using AI systems (AIS) as highly accurate diagnostic tools, the field of quality assurance in AIS is still in its early stages. Our Part I manuscript focused on the development and technical validation of an AIS. In Part II, we explore the next step in development: external validation (i.e., in silico testing). This phase is a critical quality assurance component for any AIS intended for medical use, ensuring that high-quality diagnostics remain the standard in veterinary medicine. The quality assurance process for evaluating an AIS involves rigorous: (1) investigation of sources of bias, (2) application of calibration methods and prediction of uncertainty, (3) implementation of safety monitoring systems, and (4) assessment of repeatability and robustness. Testing with unseen data is an essential part of in silico testing, as it ensures the accuracy and precision of the AIS output.
期刊介绍:
Veterinary Clinical Pathology is the official journal of the American Society for Veterinary Clinical Pathology (ASVCP) and the European Society of Veterinary Clinical Pathology (ESVCP). The journal''s mission is to provide an international forum for communication and discussion of scientific investigations and new developments that advance the art and science of laboratory diagnosis in animals. Veterinary Clinical Pathology welcomes original experimental research and clinical contributions involving domestic, laboratory, avian, and wildlife species in the areas of hematology, hemostasis, immunopathology, clinical chemistry, cytopathology, surgical pathology, toxicology, endocrinology, laboratory and analytical techniques, instrumentation, quality assurance, and clinical pathology education.