Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface.

IF 3 3区 工程技术 Q2 CHEMISTRY, ANALYTICAL Micromachines Pub Date : 2024-12-26 DOI:10.3390/mi16010021
Bo Wen, Liang Shen, Xiaoyang Kang
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Abstract

Minimally invasive endovascular stent electrodes are an emerging technology in neural engineering, designed to minimize the damage to neural tissue. However, conventional stent electrodes often rely on resistive welding and are relatively bulky, restricting their use primarily to large animals or thick blood vessels. In this study, the feasibility is explored of fabricating a laser welding stent electrode as small as 300 μm. A high-precision laser welding technique was developed to join micro-wire electrodes without compromising structural integrity or performance. To ensure consistent results, a novel micro-wire welding with platinum pad method was introduced during the welding process. The fabricated electrodes were integrated with stent structures and subjected to detailed electrochemical performance testing to evaluate their potential as neural interface components. The laser-welded endovascular stent electrodes exhibited excellent electrochemical properties, including low impedance and stable charge transfer capabilities. At the same time, in this study, a simulation is conducted of the electrode distribution and arrangement on the stent structure, optimizing the utilization of the available surface area for enhanced functionality. These results demonstrate the potential of the fabricated electrodes for high-performance neural interfacing in endovascular applications. The approach provided a promising solution for advancing endovascular neural engineering technologies, particularly in applications requiring compact electrode designs.

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激光焊接微丝支架电极作为微创血管内神经接口。
微创血管内支架电极是神经工程领域的一项新兴技术,旨在最大限度地减少对神经组织的损伤。然而,传统的支架电极通常依赖于电阻焊接,并且相对笨重,限制了它们主要用于大型动物或厚血管。本研究探讨了制备小至300 μm的激光焊接支架电极的可行性。在不影响结构完整性和性能的情况下,开发了一种高精度激光焊接技术来连接微丝电极。为了保证焊接结果的一致性,在焊接过程中引入了一种新型的铂垫微丝焊接方法。制备的电极与支架结构集成,并进行详细的电化学性能测试,以评估其作为神经界面组件的潜力。激光焊接血管内支架电极具有良好的电化学性能,包括低阻抗和稳定的电荷转移能力。同时,本研究对支架结构上电极的分布和排列进行了模拟,优化了可用表面积的利用率,增强了功能。这些结果证明了这种制备电极在血管内高性能神经接口应用方面的潜力。该方法为推进血管内神经工程技术提供了一个有前途的解决方案,特别是在需要紧凑电极设计的应用中。
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来源期刊
Micromachines
Micromachines NANOSCIENCE & NANOTECHNOLOGY-INSTRUMENTS & INSTRUMENTATION
CiteScore
5.20
自引率
14.70%
发文量
1862
审稿时长
16.31 days
期刊介绍: Micromachines (ISSN 2072-666X) is an international, peer-reviewed open access journal which provides an advanced forum for studies related to micro-scaled machines and micromachinery. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.
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