A drug safety evaluation of dapagliflozin for diabetic nephropathies in patients with cardiovascular risk.

IF 3.1 3区 医学 Q2 PHARMACOLOGY & PHARMACY Expert Opinion on Drug Safety Pub Date : 2025-03-01 Epub Date: 2025-02-12 DOI:10.1080/14740338.2025.2462671
Aayushi Sood, Aanchal Sawhney, Benjamin Borokhovsky, Apurva V Vyas, Rahul Gupta
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Abstract

Introduction: Diabetic nephropathy is a significant concern for patients with cardiovascular disease. Dapagliflozin, an SGLT2 inhibitor, has emerged as a promising therapeutic approach to managing diabetic nephropathy and reducing cardiovascular risk.

Areas covered: This review encompasses the research and literature search methodology, including clinical trials and real-world evidence, assessing the safety profile of Dapagliflozin in patients with diabetic nephropathy and cardiovascular risk.

Expert opinion: Dapagliflozin, an SGLT2 inhibitor, has redefined patient-centric care by simultaneously improving glycemic control, cardiovascular health, and renal outcomes in individuals with type 2 diabetes, cardiovascular disease, and nephropathy.

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达格列净治疗糖尿病肾病并发心血管疾病的安全性评价
导读:糖尿病肾病是心血管疾病患者非常关注的问题。达格列净(Dapagliflozin)是一种SGLT2抑制剂,已成为治疗糖尿病肾病和降低心血管风险的有前景的治疗方法。涵盖领域:本综述包括研究和文献检索方法,包括临床试验和现实世界证据,评估达格列净对糖尿病肾病和心血管风险患者的安全性。专家意见:SGLT2抑制剂Dapagliflozin通过同时改善2型糖尿病、心血管疾病和肾病患者的血糖控制、心血管健康和肾脏结局,重新定义了以患者为中心的护理。
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来源期刊
CiteScore
5.90
自引率
3.20%
发文量
97
审稿时长
6-12 weeks
期刊介绍: Expert Opinion on Drug Safety ranks #62 of 216 in the Pharmacology & Pharmacy category in the 2008 ISI Journal Citation Reports. Expert Opinion on Drug Safety (ISSN 1474-0338 [print], 1744-764X [electronic]) is a MEDLINE-indexed, peer-reviewed, international journal publishing review articles on all aspects of drug safety and original papers on the clinical implications of drug treatment safety issues, providing expert opinion on the scope for future development.
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