Steroid Injection Treatment for Nodulocystic Acne: A Literature Review

Abstract

Background

Nodulocystic acne is a severe form of acne characterized by inflamed nodules and cysts, often causing significant emotional distress and scarring. While oral corticosteroids are commonly used to treat nodulocystic acne, they can have systemic side effects. Intralesional corticosteroid injections offer a targeted and localized approach, reducing the risk of systemic side effects.

Objective

This literature review aims to evaluate the efficacy, safety, and tolerability of steroid injections for the treatment of nodulocystic acne.

Method

A comprehensive search of electronic databases was conducted to identify relevant studies on the use of intralesional corticosteroids for nodulocystic acne. Studies were included if they reported on the use of intralesional corticosteroids as a primary treatment modality for nodulocystic acne.

Results

The review included studies that reported on the use of intralesional corticosteroids for nodulocystic acne. The results suggest that steroid injections can be an effective treatment option, with significant reductions in lesion size and severity reported in several studies. The addition of lincomycin to intralesional corticosteroids was found to enhance therapeutic efficacy, while cold anesthesia was effective in reducing pain during injections. Proper technique and dosage are essential to minimize discomfort and reduce the risk of complications.

Conclusion

This review suggests that steroid injections can be a valuable treatment option for nodulocystic acne, offering targeted and localized delivery of corticosteroids with reduced risk of systemic side effects. Further research is needed to confirm these findings and establish optimal treatment regimens.