Lizbeth Naranjo , Carlos J. Pérez , Daniel F. Merino
{"title":"A data ensemble-based approach for detecting vocal disorders using replicated acoustic biomarkers from electroglottography","authors":"Lizbeth Naranjo , Carlos J. Pérez , Daniel F. Merino","doi":"10.1016/j.sbsr.2025.100741","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>The relevant prevalence of voice-related pathologies underscores the need for robust computer-aided diagnostic (CAD) systems capable of supporting early detection and continuous monitoring. Electroglottography (EGG), a non-invasive technique measuring vocal fold contact area, has proven valuable in identifying and diagnosing vocal disorders.</div></div><div><h3>Problem statement</h3><div>Traditional diagnostic methods struggle with the dependent nature of EGG measurements within subjects, leading to challenges in managing within-subject variability and supporting multi-class classification.</div></div><div><h3>Objectives</h3><div>This study aims to design, implement, and evaluate two ensemble-based approaches that address the dependency in EGG measurements. The goal is to enhance the detection of vocal disorders by managing within-subject variability and facilitating multi-class classification.</div></div><div><h3>Methods</h3><div>The proposed methods utilize replicated acoustic biomarkers derived from EGG signals. Simulation-based experiments were conducted to assess the robustness and effectiveness of these methods. Additionally, experiments were performed using EGG signals from the Saarbrüecken Voice Database (SVD).</div></div><div><h3>Results</h3><div>Simulation results indicate that integrating replicated data improves accuracy rates compared to non-replicated models. Experiments on SVD demonstrated the robustness of the proposed methodology across different vowels in classifying healthy individuals, patients with laryngitis, and those with vocal fold paralysis.</div></div><div><h3>Conclusion</h3><div>The data ensemble-based approaches developed effectively manage the dependent nature of EGG measurements, enhancing the detection and classification of vocal disorders. These methods can be applied to other data types where replications play a key role. Future research should focus on collecting comprehensive EGG databases and further exploring multi-class classification methods to solidify EGG and machine learning as a valuable tool for non-invasive assessment of laryngeal function.</div></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"47 ","pages":"Article 100741"},"PeriodicalIF":5.4000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sensing and Bio-Sensing Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214180425000078","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
The relevant prevalence of voice-related pathologies underscores the need for robust computer-aided diagnostic (CAD) systems capable of supporting early detection and continuous monitoring. Electroglottography (EGG), a non-invasive technique measuring vocal fold contact area, has proven valuable in identifying and diagnosing vocal disorders.
Problem statement
Traditional diagnostic methods struggle with the dependent nature of EGG measurements within subjects, leading to challenges in managing within-subject variability and supporting multi-class classification.
Objectives
This study aims to design, implement, and evaluate two ensemble-based approaches that address the dependency in EGG measurements. The goal is to enhance the detection of vocal disorders by managing within-subject variability and facilitating multi-class classification.
Methods
The proposed methods utilize replicated acoustic biomarkers derived from EGG signals. Simulation-based experiments were conducted to assess the robustness and effectiveness of these methods. Additionally, experiments were performed using EGG signals from the Saarbrüecken Voice Database (SVD).
Results
Simulation results indicate that integrating replicated data improves accuracy rates compared to non-replicated models. Experiments on SVD demonstrated the robustness of the proposed methodology across different vowels in classifying healthy individuals, patients with laryngitis, and those with vocal fold paralysis.
Conclusion
The data ensemble-based approaches developed effectively manage the dependent nature of EGG measurements, enhancing the detection and classification of vocal disorders. These methods can be applied to other data types where replications play a key role. Future research should focus on collecting comprehensive EGG databases and further exploring multi-class classification methods to solidify EGG and machine learning as a valuable tool for non-invasive assessment of laryngeal function.
期刊介绍:
Sensing and Bio-Sensing Research is an open access journal dedicated to the research, design, development, and application of bio-sensing and sensing technologies. The editors will accept research papers, reviews, field trials, and validation studies that are of significant relevance. These submissions should describe new concepts, enhance understanding of the field, or offer insights into the practical application, manufacturing, and commercialization of bio-sensing and sensing technologies.
The journal covers a wide range of topics, including sensing principles and mechanisms, new materials development for transducers and recognition components, fabrication technology, and various types of sensors such as optical, electrochemical, mass-sensitive, gas, biosensors, and more. It also includes environmental, process control, and biomedical applications, signal processing, chemometrics, optoelectronic, mechanical, thermal, and magnetic sensors, as well as interface electronics. Additionally, it covers sensor systems and applications, µTAS (Micro Total Analysis Systems), development of solid-state devices for transducing physical signals, and analytical devices incorporating biological materials.