Christine M.E. Kriebisch , Olga Bantysh , Lorena Baranda Pellejero , Andrea Belluati , Eva Bertosin , Kun Dai , Maria de Roy , Hailin Fu , Nicola Galvanetto , Julianne M. Gibbs , Samuel Santhosh Gomez , Gaetano Granatelli , Alessandra Griffo , Maria Guix , Cenk Onur Gurdap , Johannes Harth-Kitzerow , Ivar S. Haugerud , Gregor Häfner , Pranay Jaiswal , Sadaf Javed , Job Boekhoven
{"title":"A roadmap toward the synthesis of life","authors":"Christine M.E. Kriebisch , Olga Bantysh , Lorena Baranda Pellejero , Andrea Belluati , Eva Bertosin , Kun Dai , Maria de Roy , Hailin Fu , Nicola Galvanetto , Julianne M. Gibbs , Samuel Santhosh Gomez , Gaetano Granatelli , Alessandra Griffo , Maria Guix , Cenk Onur Gurdap , Johannes Harth-Kitzerow , Ivar S. Haugerud , Gregor Häfner , Pranay Jaiswal , Sadaf Javed , Job Boekhoven","doi":"10.1016/j.chempr.2024.102399","DOIUrl":null,"url":null,"abstract":"<div><div>The synthesis of life from non-living matter has captivated and divided scientists for centuries. This bold goal aims at unraveling the fundamental principles of life and leveraging its unique features, such as its resilience, sustainability, and ability to evolve. Synthetic life represents more than an academic milestone—it has the potential to revolutionize biotechnology, medicine, and materials science. Although the fields of synthetic biology, systems chemistry, and biophysics have made great strides toward synthetic life, progress has been hindered by social, philosophical, and technical challenges, such as vague goals, misaligned interdisciplinary efforts, and incompletely addressing public and ethical concerns. Our perspective offers a roadmap toward the synthesis of life based on discussions during a 2-week workshop with scientists from around the globe.</div></div>","PeriodicalId":268,"journal":{"name":"Chem","volume":"11 3","pages":"Article 102399"},"PeriodicalIF":19.6000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chem","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2451929424006442","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/6 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The synthesis of life from non-living matter has captivated and divided scientists for centuries. This bold goal aims at unraveling the fundamental principles of life and leveraging its unique features, such as its resilience, sustainability, and ability to evolve. Synthetic life represents more than an academic milestone—it has the potential to revolutionize biotechnology, medicine, and materials science. Although the fields of synthetic biology, systems chemistry, and biophysics have made great strides toward synthetic life, progress has been hindered by social, philosophical, and technical challenges, such as vague goals, misaligned interdisciplinary efforts, and incompletely addressing public and ethical concerns. Our perspective offers a roadmap toward the synthesis of life based on discussions during a 2-week workshop with scientists from around the globe.
期刊介绍：
Chem, affiliated with Cell as its sister journal, serves as a platform for groundbreaking research and illustrates how fundamental inquiries in chemistry and its related fields can contribute to addressing future global challenges. It was established in 2016, and is currently edited by Robert Eagling.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
