Prasenjit Das, Gouri Chakraborty, Jasreen Kaur, Sanjay K. Mandal
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引用次数: 0
Abstract
Porous functional metal organic frameworks (MOFs) have showcased their potential in biomedical applications, specifically in drug delivery systems (DDSs), due to high surface area, tailorable pore size, tunable functionality, etc. In this work, the efficient nano drug carrier behavior of a Zn-MOF is reported for two highly utilized drugs, 5-fluorouracil and calcein. It exhibits a high drug loading capacity and a slow, sustained release profile as monitored by the spectroscopic and microscopic techniques. Utilizing these two drugs, its good anticancer activity against the human breast cancer MCF-7 cell is established.
期刊介绍：
Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments.
With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology.
Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.
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